Table 3 Comparison of serum concentrations of lipid biomarkers and tryptophan metabolites in individuals with the absence (MADRS score ≤ 6) of and with the presence (MADRS score > 6) of mild to severe depressive symptoms
|  | Individuals with absence of depressive symptoms (n = 33) | Individuals with mild to severe depressive symptoms (n = 49) | F | Sig | Partial eta squared |
|---|---|---|---|---|---|
2-AG (pmol/mL) | 23.28 ± 16.71 (17.26–29.30) | 53.00 ± 75.58 (31.52–74.48) | 4.560 | 0.036 | 0.057 |
2-OG (pmol/mL) | 500.3 ± 395.1 (357.9–642.8) | 402.3 ± 398.2 (289.1–515.4) | 2.302 | 0.133 | 0.029 |
AEA (pmol/mL) | 1.52 ± 0.62 (1.30–1.74) | 1.79 ± 0.68 (1.60–1.99) | 0.332 | 0.566 | 0.004 |
OEA (pmol/mL) | 8.33 ± 4.28 (6.78–9.87) | 8.12 ± 2.95 (7.27–8.96) | 1.587 | 0.212 | 0.020 |
PEA (pmol/mL) | 6.80 ± 2.83 (5.78–7.82) | 7.18 ± 2.93 (6.34–8.01) | 0.027 | 0.869 | 0.000 |
Trp (µg/mL) | 13.60 ± 2.64 (12.64–14.55) | 11.17 ± 2.14 (10.56–11.77) | 9.791 | 0.002 | 0.114 |
Kyn (ng/mL) | 226.7 ± 110.6 (186.8–266.6) | 292.7 ± 84.5 (268.6–316.6) | 1.668 | 0.201 | 0.021 |
Kyn/Trp*1000 | 17.22 ± 8.96 (13.98–20.45) | 27.30 ± 10.16 (24.41–30.19) | 5.577 | 0.021 | 0.068 |
5-HT (ng/mL) | 276.2 ± 155.9 (220.0–332.4) | 190.9 ± 144.6 (149.7–231.9) | 2.495 | 0.118 | 0.032 |