Fig. 5
From: Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma
Potentially actionable alterations in MSI-H and MSS cancer based on the OncoKB database. A, B Level I of the proportions of MSI-H (100% vs. 0%) and TMB-H (100% vs. 8.7%) in MSI-H and MSS cancer. C, E Flow diagram in the upper part shows the list of translational targets for each OncoKB recommendation level in MSI-H, and the lower part presents the MSS cholangiocarcinoma. The widths of the belts indicate different frequencies for each target at every level. D, F The upper and lower pie plot shows the distribution of OncoKB levels for translational targets in patients with MSI-H or MSS cholangiocarcinoma. MSI-H, microsatellite instability-high; MSS, microsatellite stability; TMB-H, tumor mutation burden-high