Table 2 Univariate and multivariate Cox proportional hazards analyses of ASCVD events after PSM

ICIs

 No

Reference

 Yes

5.166 (1.969, 13.553)

 < 0.001

5.104 (1.942, 13.416)

 < 0.001

Sex

 Female

Reference

 Male

0.602 (0.245, 1.477)

0.268

Age

 < 65

Reference

 ≥ 65

1.775 (0.847, 3.718)

0.128

Body mass index (kg/m²)

0.942 (0.830, 1.069)

0.353

Hypertension

 No

Reference

 Yes

1.580 (0.759, 3.279)

0.221

Diabetes

 No

Reference

 Yes

0.819 (0.195, 3.446)

0.786

Smoking index

 ≤ 400

Reference

 > 400

2.066 (0.993, 2.292)

0.052

1.709 (0.810, 3.610)

0.159

Hyperlipidemia

 No

Reference

 Yes

0.957 (0.333, 2.751)

0.936

History of cardiovascular disease

 No

Reference

 Yes

2.981 (1.273, 6.983)

0.012

2.801 (1.176, 6.671)

0.020

Stages

 Stage III

Reference

 Stage IV

1.511 (0.632, 3.610)

0.354

Chest radiation therapy

 No

Reference

 Yes

1.580 (0.719, 3.471)

0.254

Statins

 No

Reference

 Yes

0.931 (0.221, 3.921)

0.923

Aspirin

 No

Reference

 Yes

2.564 (0.776, 8.477)

0.123

Hemoglobin (g/L)

1.000 (0.979, 1.022)

0.997

Neutrophil-to-lymphocyte ratio

1.013 (0.961, 1.068)

0.632

Platelet count-to-lymphocyte ratio

1.000 (0.997, 1.002)

0.763