Fig. 7
Distribution and levels of TEAD4 and HIF1A in human placental villi. A and F Immunohistochemical analysis of TEAD4 (A) and HIF1A (F) staining in pregnant women during the first trimester (n = 6), third trimester (n = 6), and preeclampsia (n = 6). B and G mRNA levels of TEAD4 (HC group, n = 12; PE group, n = 12) (B) and HIF1A (HC group, n = 11; PE group, n = 11) (G) in women with preeclampsia and healthy controls. C The TEAD4 mRNA level correlated positively with the mRNA level of MLL1 in placental villi in PE and HC. D, E, H and I Western blots (D and H) and corresponding quantification (E and I) of TEAD4 (HC group, n = 6; PE group, n = 6) and HIF1A (HC group, n = 5; PE group, n = 5) in the PE and control women. Data are presented as the means ± SD. **P < 0.01, *P < 0.05