Table 1 Gestational age, gender, birth body weight, and outcome in different models and sets
No. (%) | ||||
|---|---|---|---|---|
2010–2014 original cohort | 2010–2014 development set (balanced) | 2010–2014 independent test | 2016–2017 external test | |
Variables | ||||
CDelay: BSIDIII cognitive score < 85 at 24 months CA | ||||
(n = 2544) | (n = 532) | (n = 763) | (n = 1347) | |
GA, mean (SD), weeks | 28.0 (2.0) | 27.8 (2.0) | 27.9 (2.0) | 27.9 (2.1) |
Male, N (%) | 1295 (50.9) | 285 (53.6) | 423 (55.4) | 716 (53.2) |
BBW, N (%) | ||||
BBW≦ − 3Z | 24 (0.9) | 4 (0.7) | 6 (0.8) | 75 (5.6) |
− 3Z < BBW ≦ − 2Z | 69 (2.7) | 14 (2.6) | 20 (2.6) | 89 (6.6) |
− 2Z < BBW ≦ − Z | 179 (7.1) | 42 (7.9) | 60 (7.9) | 245 (18.2) |
− Z < BBW ≦ mean | 403 (15.8) | 83 (15.6) | 120 (15.7) | 568 (42.2) |
Mean < BBW ≦ Z | 1161 (45.7) | 237 (44.6) | 342 (44.8) | 349 (25.9) |
Z < BBW ≦ 2Z | 665 (26.1) | 143 (26.9) | 201 (26.4) | 20 (1.4) |
2Z < BBW ≦ 3Z | 42 (1.6) | 9 (1.7) | 14 (1.8) | 1 (0.1) |
3Z < BBW | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) |
NDI outcome, N (%) | 390 (15.3) | 266 (50.0) | 114 (14.9) | 216 (16.0) |
MDelay: BSIDIII motor score < 85 at 24 months CA | ||||
(n = 2544) | (n = 660) | (n = 763) | (n = 1347) | |
GA, mean (SD), weeks | 28.0 (2.0) | 27.7 (2.1) | 27.9 (2.0) | 27.9 (2.1) |
Male, N (%) | 1295 (50.9) | 356 (53.9) | 423 (55.4) | 716 (53.2) |
BBW, N (%) | ||||
BBW≦ − 3Z | 24 (0.9) | 11 (1.7) | 6 (0.8) | 75 (5.6) |
− 3Z < BBW ≦ − 2Z | 69 (2.7) | 19 (2.9) | 20 (2.6) | 89 (6.6) |
− 2Z < BBW ≦ − Z | 179 (7.1) | 44 (6.6) | 60 (7.9) | 245 (18.2) |
− Z < BBW ≦ mean | 403 (15.8) | 102 (15.5) | 120 (15.7) | 568 (42.2) |
Mean < BBW ≦ Z | 1161 (45.7) | 296 (44.9) | 342 (44.8) | 349 (25.9) |
Z < BBW ≦ 2Z | 665 (26.1) | 180 (27.3) | 201 (26.4) | 20 (1.4) |
2Z < BBW ≦ 3Z | 42 (1.6) | 8 (1.2) | 14 (1.8) | 1 (0.1) |
3Z < BBW | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) |
NDI outcome, N (%) | 471 (18.5) | 330 (50.0) | 141 (18.5) | 275 (20.4) |
CRegres: BSIDIII cognitive score declines ≧ 15 between 6 and 24 months CA | ||||
(n = 2544) | (n = 846) | (n = 763) | (n = 1347) | |
GA, mean (SD), weeks | 28.0 (2.0) | 28.0 (2.0) | 27.9 (2.0) | 27.9 (2.1) |
Male, N (%) | 1295 (50.9) | 421 (49.8) | 423 (55.4) | 716 (53.2) |
BBW, N (%) | ||||
BBW ≦ − 3Z | 24 (0.9) | 9 (1.0) | 6 (0.8) | 75 (5.6) |
− 3Z < BBW ≦ − 2Z | 69 (2.7) | 25 (3.0) | 20 (2.6) | 89 (6.6) |
− 2Z < BBW ≦ − Z | 179 (7.1) | 67 (7.9) | 60 (7.9) | 245 (18.2) |
− Z < BBW ≦ mean | 403 (15.8) | 218 (25.8) | 120 (15.7) | 568 (42.2) |
Mean < BBW ≦ Z | 1161 (45.7) | 370 (43.7) | 342 (44.8) | 349 (25.9) |
Z < BBW ≦ 2Z | 665 (26.1) | 141 (16.7) | 201 (26.4) | 20 (1.4) |
2Z < BBW ≦ 3Z | 42 (1.6) | 15 (1.8) | 14 (1.8) | 1 (0.1) |
3Z < BBW | 1 (0.1) | 1 (0.1) | 0 (0) | 0 (0) |
NDI outcome, N (%) | 604 (23.7) | 423 (50.0) | 181 (23.7) | 351 (26.1) |
MRegres: BSIDIII motor score declines ≧ 15 between 6 and 24 months CA | ||||
(n = 2544) | (n = 696) | (n = 763) | (n = 1347) | |
GA, mean (SD), weeks | 28.0 (2.0) | 28.1 (1.9) | 27.9 (2.0) | 27.9 (2.1) |
Male, N (%) | 1295 (50.9) | 352 (50.6) | 423 (55.4) | 716 (53.2) |
BBW, N (%) | ||||
BBW≦ − 3Z | 24 (0.9) | 4 (0.6) | 6 (0.8) | 75 (5.6) |
− 3Z < BBW ≦ − 2Z | 69 (2.7) | 17 (2.4) | 20 (2.6) | 89 (6.6) |
− 2Z < BBW ≦ − Z | 179 (7.1) | 32 (4.6) | 60 (7.9) | 245 (18.2) |
− Z < BBW ≦ mean | 403 (15.8) | 100 (14.4) | 120 (15.7) | 568 (42.2) |
Mean < BBW ≦ Z | 1161 (45.7) | 338 (48.6) | 342 (44.8) | 349 (25.9) |
Z < BBW ≦ 2Z | 665 (26.1) | 195 (28.0) | 201 (26.4) | 20 (1.4) |
2Z < BBW ≦ 3Z | 42 (1.6) | 9 (1.3) | 14 (1.8) | 1 (0.1) |
3Z < BBW | 1 (0.1) | 1 (0.1) | 0 (0) | 0 (0) |
NDI outcome, N (%) | 491 (19.3) | 342 (49.1) | 149 (19.5) | 288 (21.4) |