Table 3 Crude and adjusted hazard ratios (HRs) for the association of sex steroid treatment with death due to COVID-19
Exposed | Unexposed | |||||
|---|---|---|---|---|---|---|
Exposure | Total person-time (in years) | n events (%) | Total person-time (in years) | n events (%) | Crude HR (95% CI) | Adjusted HR (95% CI)a |
Local estrogens alone | 9438 | 50 (0.50) | 47,146 | 114 (0.23) | 2.19 (1.57–3.06) | 2.02 (1.45–2.81) |
Systemic estrogens without progestogens | 3100 | 5 (0.16) | 15,503 | 4 (0.03) | 6.26 (1.68–23.30) | 6.39 (1.69–24.21) |
Estrogens and progestogens | 8341 | 0 (0.00) | 41,692 | 4 (0.01) | - | - |
Progestogens alone | 9272 | 2 (0.02) | 46,354 | 7 (0.02) | 1.43 (0.30–6.88) | 1.95 (0.41–9.42) |
Tibolone alone | 922 | 0 (0.00) | 4615 | 0 (0.00) | - | - |