Table 7 Crude and adjusted Cox regression models evaluating the effect of treatment cessation in relation to death due to COVID-19 (i.e., restricting the analyses among those with ongoing treatment as opposed to ever treatment)
Death due to COVID-19 | ||||||
|---|---|---|---|---|---|---|
Exposed | Unexposed | |||||
Exposure | Person time (in years) | n events (%) | Person time (in years) | n events (%) | Crude HR (95% CI) | Adjusted HR (95% CI) |
Local estrogens alone | 3964 | 21 | 19,813 | 55 | 1.55 (0.94–2.56) | 1.71 (1.03–2.82) |
Systemic estrogens without progestogens | 1240 | 2 | 6200 | 0 | NE | NE |
Systemic estrogens and progestogens | 3248 | 0 | 16,236 | 0 | NE | NE |
Progestogens alone | 4636 | 1 | 23,180 | 2 | 0.96 (0.09–10.57) | 0.65 (0.05–7.83) |
Tibolone alone | 359 | 0 | 1794 | 0 | NE | NE |