Variables | ECAS ( +) n = 6,390 | ECAS (-) n = 28,093 | P value |
---|---|---|---|
Age, years; mean value (SD) | 77.55 (9.93) | 76.75 (10.64) | < 0.001 |
Age ≥ 75 years, n (%) | 4274 (66.89) | 17966 (63.95) | < 0.001 |
Age 65–74 years, n (%) | 1409 (22.05) | 6272 (22.33) | 0.632 |
Male gender, n (%) | 3923 (61.39) | 14451 (51.44) | < 0.001 |
Comorbidities, n (%) | |||
Hypertension | 5798 (90.74) | 24660 (87.78) | < 0.001 |
Diabetes mellitus | 2743 (42.93) | 11610 (41.33) | 0.019 |
Congestive heart failure | 3002 (46.98) | 14333 (51.02) | < 0.001 |
Vascular diseases | 1092 (17.09) | 3372 (12) | < 0.001 |
COPD | 2098 (32.83) | 8084 (28.78) | < 0.001 |
Hyperlipidemia | 3321 (51.97) | 11355 (40.42) | < 0.001 |
Autoimmune diseases | 355 (5.56) | 1207 (4.3) | < 0.001 |
Cancer | 832 (13.02) | 3060 (10.89) | < 0.001 |
Hyperthyroidism | 205 (3.21) | 733 (2.61) | 0.013 |
Abnormal renal function | 1559 (24.4) | 5401 (19.23) | < 0.001 |
Abnormal liver function | 1065 (16.67) | 4123 (14.68) | < 0.001 |
Anemia | 1028 (16.09) | 4351 (15.49) | 0.233 |
History of bleeding | 2104 (32.93) | 8825 (31.41) | 0.020 |
Alcohol excess/abuse | 130 (2.03) | 462 (1.64) | 0.043 |
Gout | 1648 (25.79) | 6326 (22.52) | < 0.001 |
CHA2DS2-VASc score; mean values (SD) | 5.92 (1.36) | 5.91 (1.38) | 0.515 |
HAS-BLED score, mean value (SD) | 4.14 (1.13) | 3.91 (1.11) | < 0.001 |