Table 2 Proteomic markers significantly associated with specific sleep duration quintiles when compared to referent sleep duration (quintile 3) using tenfold cross-fit partialing out lasso logistic regression analyses

Quintile 1 vs Quintile 3

TRANCE

 − 0.199

0.084

 − 2.37

0.018

 − 0.363 to − 0.035

MMP-7

0.193

0.082

2.37

0.018

0.033 to 0.353

MMP-10

 − 0.160

0.069

 − 2.32

0.020

 − 0.295 to − 0.025

Follistatin

0.206

0.091

2.25

0.024

0.027 to 0.385

E-selectin

0.201

0.091

2.22

0.027

0.023 to 0.378

TRAIL-R2

0.266

0.133

2.00

0.046

0.005 to 0.528

Quintile 2 vs Quintile 3

TRAIL-R2

0.431

0.143

3.02

0.0026

0.151 to 0.711

FAS

 − 0.457

0.156

 − 2.92

0.0035

 − 0.763 to − 0.150

Kallikrein-6

 − 0.284

0.111

 − 2.57

0.010

 − 0.500 to − 0.067

U-PAR

 − 0.302

0.140

 − 2.16

0.031

 − 0.576 to − 0.0280

Quintile 4 vs Quintile 3

FAS

 − 0.452

0.135

 − 3.34

0.00084

 − 0.717 to − 0.187

Renin

0.186

0.070

2.64

0.0082

0.048 to 0.324

HB-EGF

 − 0.329

0.135

 − 2.44

0.015

 − 0.594 to − 0.064

MMP-7

0.189

0.081

2.34

0.019

0.031 to 0.348

CXCL6

0.210

0.097

2.16

0.031

0.019 to 0.400

Quintile 5 vs Quintile 3

Prolactin

0.261

0.081

3.22

0.0013

0.102 to 0.420

MMP-7

0.296

0.097

3.05

0.0023

0.106 to 0.486

CXCL1

0.245

0.100

2.44

0.015

0.0483 to 0.441

FAS

 − 0.402

0.170

 − 2.37

0.018

 − 0.735 to − 0.070

tPA

0.256

0.110

2.32

0.020

0.0395 to 0.472

HSP27

 − 0.284

0.130

 − 2.19

0.029

 − 0.538 to − 0.030