Table 2 Comparison of variables pre-HCL vs post-HCL commencement at 3, 6, and 12 months

Variables

Before HCL (n = 251)

3 months after HCL (n = 239)

Difference (95% confidence interval)

P value

HbA1c (mmol/mol)

62.3 ± 12.1

54.1 ± 7.9

7.7 (6.5 to 8.9)

P < 0.001

TIR (%)

48.7 ± 15.3

64.7 ± 11.8

 − 15.8 (− 17.6 to − 14.1)

P < 0.001

Hypoglycaemia (%)

3.6 ± 3.8

2.4 ± 2.7

1.3 (0.7 to 1.74)

P < 0.001

Variables

Before HCL (n = 251)

6 months after HCL (n = 226)

Difference (95% confidence interval)

P value

HbA1c (mmol/mol)

62.3 ± 12.1

55.3 ± 9.3

7.0 (5.8 to 8.2)

P < 0.001

TIR (%)

48.7 ± 15.3

63.0 ± 12.4

 − 14.3 (− 15.9 to − 12.4)

P < 0.001

Hypoglycaemia (%)

3.6 ± 3.8

2.4 ± 2.2

1.2 (0.82 to 1.74)

P < 0.001

Variables

Before HCL (n = 251)

12 months after HCL (n = 221)

Difference (95% confidence interval)

P value

HbA1c (mmol/mol)

62.3 ± 12.1

55.4 ± 12.2

6.9 (5.8 to 8.4)

P < 0.001

TIR (%)

48.7 ± 15.3

62.0 ± 12.0

 − 13.3 (− 15.4 to − 11.4)

P < 0.001

Hypoglycaemia (%)

3.6 ± 3.8

2.0 ± 1.6

1.6 (0.9 to 1.9)

P < 0.001