Riley LW, Remis RS, Helgerson SD, McGee HB, Wells JG, Davis BR, Hebert RJ, Olcott ES, Johnson LM, Hargrett NT, Blake PA, Cohen ML: Hemorrhagic colitis associated with a rare Escherichia coli serotype. N Engl J Med. 1983, 308: 681-685. 10.1056/NEJM198303243081203.
Article
CAS
PubMed
Google Scholar
Goldwater PN: Pathogenesis and Treatment strategies. BMC Medicine.
Gould LH, Demma L, Jones TF, Hurd S, Vugia DJ, Smith K, Shiferaw B, Segler S, Palmer A, Zansky S, Griffin PM: Hemolytic uremic syndrome and death in persons with Escherichia coli O157:H7 infection, foodborne diseases active surveillance network sites, 2000-2006. Clin Infect Dis. 2009, 49: 480-1485. 10.1086/600821.
Article
Google Scholar
Gerber A, Karch H, Allerberger F, Verweyen HM, Zimmerhackl LB: Clinical course and the role of shiga toxin-producing Escherichia coli infection in the hemolytic-uremic syndrome in pediatric patients, 1997-2000, in Germany and Austria: a prospective study. J Infect Dis. 2002, 186: 493-500. 10.1086/341940.
Article
PubMed
Google Scholar
Alpers K, Werber D, Frank C, Koch J, Friedrich AW, Karch H, An Der Heiden M, Prager R, Fruth A, Bielaszewska M, Morlock G, Heissenhuber A, Diedler A, Gerber A, Ammon A: Sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- causes another outbreak of haemolytic uraemic syndrome in children. Epidemiol Infect. 2009, 137: 389-395. 10.1017/S0950268808001465.
Article
CAS
PubMed
Google Scholar
Konowalchuk J, Speirs JI, Stavric S: Vero response to a cytotoxin of Escherichia coli. Infect Immun. 1977, 18: 775-779.
CAS
PubMed
PubMed Central
Google Scholar
Tarr PI, Gordon CA, Chandler WL: Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet. 2005, 365: 1073-1086.
CAS
PubMed
Google Scholar
Werber D, Fruth A, Heissenhuber A, Wildner M, Prager R, Tschape H, Ammon A: Shiga toxin-producing Escherichia coli O157 more frequently cause bloody diarrhea than do non-O157 strains. J Infect Dis. 2004, 189: 1335-1336. 10.1086/382282.
Article
CAS
PubMed
Google Scholar
Werber D, Behnke SC, Fruth A, Merle R, Menzler S, Glaser S, Kreienbrock L, Prager R, Tschape H, Roggentin P, Bockemuhl J, Ammon A: Shiga Toxin-producing Escherichia coli Infection in Germany-Different Risk Factors for Different Age Groups. Am J Epidemiol. 2007, 165: 425-434.
Article
PubMed
Google Scholar
Robert Koch Institute: EHEC-Erkrankung. Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten für 2010. Edited by: Robert Koch Institute. 2011, Berlin: AZ Druck und Datentechnik GmbH, 80-84.
Google Scholar
Brooks JT, Sowers EG, Wells JG, Greene KD, Griffin PM, Hoekstra RM, Strockbine NA: Non-O157 Shiga toxin-producing Escherichia coli infections in the United States, 1983-2002. J Infect Dis. 2005, 192: 1422-1429. 10.1086/466536.
Article
PubMed
Google Scholar
Werber D, Frank C, Wadl M, Karch H, Fruth A, Stark K: Looking for tips to find icebergs-surveillance of haemolytic uraemic syndrome to detect outbreaks of Shiga toxin-producing E. coli infection. Euro Surveill. 2008, 13: pii:8053.
Google Scholar
Hoefer D, Hurd S, Medus C, Cronquist A, Hanna S, Hatch J, Hayes T, Larson K, Nicholson C, Wymore K, Tobin-D'Angelo M, Strockbine N, Snippes P, Atkinson R, Griffin PM, Gould LH: Laboratory practices for the identification of Shiga toxin-producing Escherichia coli in the United States, FoodNet sites, 2007. Foodborne Pathog Dis. 2011, 8: 555-560. 10.1089/fpd.2010.0764.
Article
PubMed
Google Scholar
Wiedenbeck J, Cohan FM: Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches. FEMS Microbiol Rev. 2011, 35: 957-976. 10.1111/j.1574-6976.2011.00292.x.
Article
CAS
PubMed
Google Scholar
Robins-Browne RM: The relentless evolution of pathogenic Escherichia coli. Clin Infect Dis. 2005, 41: 793-794. 10.1086/432725.
Article
PubMed
Google Scholar
Michino H, Araki K, Minami S, Takaya S, Sakai N, Miyazaki M, Ono A, Yanagawa H: Massive outbreak of Escherichia coli O157:H7 infection in schoolchildren in Sakai City, Japan, associated with consumption of white radish sprouts. Am J Epidemiol. 1999, 150: 787-796.
Article
CAS
PubMed
Google Scholar
Matsell DG, White CT: An outbreak of diarrhea-associated childhood hemolytic uremic syndrome: the Walkerton epidemic. Kidney Int Suppl. 2009, S35-S37. 112
Bell BP, Goldoft M, Griffin PM, Davis MA, Gordon DC, Tarr PI, Bartleson CA, Lewis JH, Barrett TJ, Wells JG, et al: A multistate outbreak of Escherichia coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers. The Washington experience. JAMA. 1994, 272: 1349-1353. 10.1001/jama.1994.03520170059036.
Article
CAS
PubMed
Google Scholar
Ahn CK, Klein E, Tarr PI: Isolation of patients acutely infected with Escherichia coli O157:H7: low-tech, highly effective prevention of hemolytic uremic syndrome. Clin Infect Dis. 2008, 46: 1197-1199. 10.1086/587664.
Article
PubMed
Google Scholar
Frank C, Werber D, Cramer JP, Askar M, Faber M, Heiden MA, Bernard H, Fruth A, Prager R, Spode A, Wadl M, Zoufaly A, Jordan S, Kemper MJ, Follin P, Muller L, King LA, Rosner B, Buchholz U, Stark K, Krause G, HUS Investigation Team: Epidemic Profile of Shiga-Toxin-Producing Escherichia coli O104:H4 Outbreak in Germany. N Engl J Med. 2011, 365: 1771-1780. 10.1056/NEJMoa1106483.
Article
CAS
PubMed
Google Scholar
Harendza S: "HUS diary" of a German nephrologist during the current EHEC outbreak in Europe. Kidney Int. 2011, 80: 687-689. 10.1038/ki.2011.238.
Article
PubMed
Google Scholar
Rohde H, Qin J, Cui Y, Li D, Loman NJ, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao GF, Song Y, Li Y, Yang H, et al: Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med. 2011, 365: 718-724. 10.1056/NEJMoa1107643.
Article
CAS
PubMed
Google Scholar
Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H: Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology. PLoS One. 2011, 6: e22751-10.1371/journal.pone.0022751.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brzuszkiewicz E, Thurmer A, Schuldes J, Leimbach A, Liesegang H, Meyer FD, Boelter J, Petersen H, Gottschalk G, Daniel R: Genome sequence analyses of two isolates from the recent Escherichia coli outbreak in Germany reveal the emergence of a new pathotype: Entero-Aggregative-Haemorrhagic Escherichia coli (EAHEC). Arch Microbiol. 2011, 193: 883-891. 10.1007/s00203-011-0725-6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Moller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK: Origins of the E. coli strain causing an outbreak of Hemolytic-Uremic Syndrome in Germany. N Engl J Med. 2011, 365: 709-717. 10.1056/NEJMoa1106920.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bielaszewska M, Mellmann A, Zhang W, Kock R, Fruth A, Bauwens A, Peters G, Karch H: Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study. Lancet Infect Dis. 2011, 11: 671-676.
Article
CAS
PubMed
Google Scholar
Buchholz U, Bernard H, Werber D, Bohmer MM, Remschmidt C, Wilking H, Delere Y, Heiden MA, Adlhoch C, Dreesman J, Ehlers J, Ethelberg S, Faber M, Frank C, Fricke G, Greiner M, Hohle M, Ivarsson S, Jark U, Kirchner M, Koch J, Krause G, Luber P, Rosner B, Stark K, Kuhne M: German Outbreak of Escherichia coli O104:H4 Associated with Sprouts. N Engl J Med. 2011, 365: 1763-1770. 10.1056/NEJMoa1106482.
Article
CAS
PubMed
Google Scholar
Frank C, Faber MS, Askar M, Bernard H, Fruth A, Gilsdorf A, Hohle M, Karch H, Krause G, Prager R, Spode A, Stark K, Werber D: Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011. Euro Surveill. 2011, 16: pii:19878.
Google Scholar
Tracing seeds, in particular fenugreek (Trigonella foenum-graecum) seeds, in relation to the Shiga toxin-producing E. coli (STEC) O104:H4 2011 Outbreaks in Germany and France. European Food Safety Authority 2011 July 5. Available from: URL: http://www.efsa.europa.eu/en/supporting/doc/176e.pdf
Federal Institute for Risk Assessment: Bedeutung von Sprossen und Keimlingen sowie Samen zur Sprossenherstellung im EHEC O104:H4 Ausbruchsgeschehen im Mai und Juni 2011. Federal Institute for Risk assessment. 2011, Available from: URL: http://www.bfr.bund.de/cm/343/bedeutung_von_sprossen_und_keimlingen_sowie_samen_zur_sprossenherstellung_im_ehec_o104_h4_ausbruchsgeschehen_im_mai_und_juni_2011.pdf
Google Scholar
Tauxe RV: Emerging foodborne diseases: an evolving public health challenge. Emerg Infect Dis. 1997, 3: 425-434. 10.3201/eid0304.970403.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hauri A, Gotsch U, Strotmann I, Krahn J, Bettge-Weller G, Westbrock H, Bellinger O, Uphoff H: Secondary transmissions during the outbreak of Shiga toxin-producing Escherichia coli O104 in Hesse, Germany, 2011. Euro Surveill. 2011, 16: pii:19937.
Google Scholar
Werber D, Fruth A, Frank C, Altmann D, Stark K: Surveillance von STEC-Erkrankungen in Deutschland 2001-2009: Time for a change. Dritter EHEC-Workshop, 2010. Edited by: Busch U. 2010, Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, 16.
Google Scholar
Bugarel M, Beutin L, Martin A, Gill A, Fach P: Micro-array for the identification of Shiga toxin-producing Escherichia coli (STEC) seropathotypes associated with Hemorrhagic Colitis and Hemolytic Uremic Syndrome in humans. Int J Food Microbiol. 2010, 142: 318-329. 10.1016/j.ijfoodmicro.2010.07.010.
Article
PubMed
Google Scholar
Swaminathan B, Gerner-Smidt P, Ng LK, Lukinmaa S, Kam KM, Rolando S, Gutierrez EP, Binsztein N: Building PulseNet International: an interconnected system of laboratory networks to facilitate timely public health recognition and response to foodborne disease outbreaks and emerging foodborne diseases. Foodborne Pathog Dis. 2006, 3: 36-50. 10.1089/fpd.2006.3.36.
Article
PubMed
Google Scholar
Tauxe RV: Molecular subtyping and the transformation of public health. Foodborne Pathog Dis. 2006, 3: 4-8. 10.1089/fpd.2006.3.4.
Article
CAS
PubMed
Google Scholar
Salmon RL, Evans MR, Mason BW, Werber D: Bloody diarrhoea: Test early for verotoxin producing Escherichia coli. BMJ. 2008, 336: 1147-1148.
Article
PubMed
PubMed Central
Google Scholar
Wadl M, Rieck T, Nachtnebel M, Greutelaers B, An Der Heiden M, Altmann D, Hellenbrand W, Faber M, Frank C, Schweickert B, Krause G, Benzler J, Eckmanns T: Enhanced surveillance during a large outbreak of bloody diarrhoea and haemolytic uraemic syndrome caused by Shiga toxin/verotoxin-producing Escherichia coli in Germany, May to June 2011. Euro Surveill. 2011, 16: pii:19893.
Google Scholar
King LA, Mailles A, Mariani-Kurkdjian P, Vernozy-Rozand C, Montet MP, Grimont F, Pihier N, Devalk H, Perret F, Bingen E, Espie E, Vaillant V: Community-wide outbreak of Escherichia coli O157:H7 associated with consumption of frozen beef burgers. Epidemiol Infect. 2009, 137: 889-896. 10.1017/S0950268808001490.
Article
CAS
PubMed
Google Scholar
Community outbreak of hemolytic uremic syndrome attributable to Escherichia coli O111:NM-South Australia 1995. MMWR Morb Mortal Wkly Rep. 1995, 44: 550-558.
Nielsen S, Frank C, Fruth A, Spode A, Prager R, Graff A, Plenge-Bonig A, Loos S, Lutgehetmann M, Kemper MJ, Muller-Wiefel DE, Werber D: Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009. Zoonoses Public Health. 2011, 58: 567-572. 10.1111/j.1863-2378.2011.01405.x.
Article
CAS
PubMed
Google Scholar
Mody RK, Greene SA, Gaul L, Sever A, Pichette S, Zambrana I, Dang T, Gass A, Wood R, Herman K, Cantwell LB, Falkenhorst G, Wannemuehler K, Hoekstra RM, McCullum I, Cone A, Franklin L, Austin J, Delea K, Behravesh CB, Sodha SV, Yee JC, Emanuel B, Al-Khaldi SF, Jefferson V, Williams IT, Griffin PM, Swerdlow DL: National outbreak of Salmonella serotype saintpaul infections: importance of Texas restaurant investigations in implicating jalapeno peppers. PLoS One. 2011, 6: e16579-10.1371/journal.pone.0016579.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fretz R, Pichler J, Sagel U, Much P, Ruppitsch W, Pietzka AT, Stoger A, Huhulescu S, Heuberger S, Appl G, Werber D, Stark K, Prager R, Flieger A, Karpiskova R, Pfaff G, Allerberger F: Update: multinational listeriosis outbreak due to 'Quargel', a sour milk curd cheese, caused by two different L. monocytogenes serotype 1/2a strains, 2009-2010. Euro Surveill. 2010, 15: pii:19543.
Google Scholar
Salmonella montevideo infections associated with salami products made with contaminated imported black and red pepper -- United States, July 2009-April 2010. MMWR Morb Mortal Wkly Rep. 2010, 59: 1647-1650.
Ethelberg S, Smith B, Torpdahl M, Lisby M, Boel J, Jensen T, Molbak K: An outbreak of Verocytotoxin-producing Escherichia coli O26:H11 caused by beef sausage, Denmark 2007. Euro Surveill. 2007, 12: E070531.4.
CAS
PubMed
Google Scholar
Keene WE, Hedberg K, Herriott DE, Hancock DD, McKay RW, Barrett TJ, Fleming DW: A prolonged outbreak of Escherichia coli O157:H7 infections caused by commercially distributed raw milk. J Infect Dis. 1997, 176: 815-818. 10.1086/517310.
Article
CAS
PubMed
Google Scholar
Outbreak of Salmonella serotype Enteritidis infections associated with raw almonds-United States and Canada, 2003-2004. MMWR Morb Mortal Wkly Rep. 2004, 53: 484-487.
Werber D, Mason BW, Evans MR, Salmon RL: Preventing household transmission of Shiga toxin-producing Escherichia coli O157 infection: promptly separating siblings might be the key. Clin Infect Dis. 2008, 46: 1189-196. 10.1086/587670.
Article
PubMed
Google Scholar
Pollock KG, Beattie TJ, Reynolds B, Stewart A, Cowden JM: Clinical management of children with suspected or confirmed E. coli O157 infection. Scott Med J. 2007, 52: 5-7.
Article
CAS
PubMed
Google Scholar
Locking ME, Pollock KG, Allison LJ, Rae L, Hanson MF, Cowden JM: Escherichia coli O157 infection and secondary spread, Scotland, 1999-2008. Emerg Infect Dis. 2011, 17: 524-527.
Article
PubMed
PubMed Central
Google Scholar