- Open Access
Passive smoking, invasive meningococcal disease and preventive measures: a commentary
© Rashid and Booy; licensee BioMed Central Ltd. 2012
- Received: 24 October 2012
- Accepted: 10 December 2012
- Published: 10 December 2012
Active smoking is a recognized risk factor of various infectious diseases. In a systematic review published in BMC Public Health, Murray et al. demonstrated that exposure to passive smoking significantly increased the risk of meningococcal disease among children. Their review especially highlights that the risk remains high even if the exposure occurs during pregnancy or after birth, although the authors could not disentangle the independent effects of smoking during pregnancy from those in the postnatal period. How passive smoking increases the risk of childhood meningococcal disease is not precisely known. Both exposure to 'smoke', or 'smokers' (who are highly susceptible to pharyngeal carriage of meningococci) are postulated mechanisms, but unfortunately very few studies have examined the risk of exposure by considering these two variables separately, and this therefore remains a research priority. Quitting may well be the mainstay of preventing tobacco-related hazards but the available global data suggest that most smokers are reluctant to quit. Among other interventions, immunizing children with a meningococcal conjugate vaccine could, theoretically, reduce the risk of meningococcal disease among children and their smoker household contacts through herd immunity.
See related article http://www.biomedcentral.com/1471-2458/12/1062
- Conjugate meningococcal vaccine
- invasive meningococcal disease
- meningococcal carriage
- passive smoking
- quitting ratio
HR is a clinical research epidemiologist at the NCIRS, Australia. He is particularly interested in the epidemiology of vaccine-preventable infections among travelers, including meningococcal disease and respiratory infections.
RB is currently the Head of Clinical Research at NCIRS, Australia. He has particular interests in meningococcal and pneumococcal disease, Hib, influenza, varicella and HPV. His research interests extend from understanding the genetic basis of susceptibility to, and severity of, infectious diseases, especially influenza and invasive disease caused by encapsulated organisms; the clinical, public health, social and economic burden of these diseases; and means by which to prevent or control serious infections through vaccines, drugs and non-pharmaceutical measures.
The authors thank Dr Jane Jelfs for providing valuable full text references.
- World Health Organization: Tobacco. Fact sheet no. 339. 2011, WHO Media Centre, [http://www.who.int/mediacentre/factsheets/fs339/en/index.html]Google Scholar
- Huttunen R, Heikkinen T, Syrjänen J: Smoking and the outcome of infection. J Intern Med. 2011, 269: 258-269. 10.1111/j.1365-2796.2010.02332.x.View ArticlePubMedGoogle Scholar
- Murray RL, Britton J, Leonardi-Bee J: Second hand smoke exposure and the risk of invasive meningococcal disease in children: systematic review and meta-analysis. BMC Public Health. 2012, 12: 1062-10.1186/1471-2458-12-1062.View ArticlePubMedPubMed CentralGoogle Scholar
- Lee CC, Middaugh NA, Howie SR, Ezzati M: Association of secondhand smoke exposure with pediatric invasive bacterial disease and bacterial carriage: a systematic review and meta-analysis. PLoS Med. 2010, 7: e1000374-10.1371/journal.pmed.1000374.View ArticlePubMedPubMed CentralGoogle Scholar
- Hodgson A, Smith T, Gagneux S, Adjuik M, Pluschke G, Mensah NK, Binka F, Genton B: Risk factors for meningococcal meningitis in northern Ghana. Trans R Soc Trop Med Hyg. 2001, 95: 477-480. 10.1016/S0035-9203(01)90007-0.View ArticlePubMedGoogle Scholar
- Stuart JM, Cartwright KA, Robinson PM, Noah ND: Effect of smoking on meningococcal carriage. Lancet. 1989, 2: 723-725.View ArticlePubMedGoogle Scholar
- Robinson P, Taylor K, Nolan T: Risk-factors for meningococcal disease in Victoria, Australia, in 1997. Epidemiol Infect. 2001, 127: 261-268.View ArticlePubMedPubMed CentralGoogle Scholar
- Stanwell-Smith RE, Stuart JM, Hughes AO, Robinson P, Griffin MB, Cartwright K: Smoking, the environment and meningococcal disease: a case control study. Epidemiol Infect. 1994, 112: 315-328. 10.1017/S0950268800057733.View ArticlePubMedPubMed CentralGoogle Scholar
- Coen PG, Tully J, Stuart JM, Ashby D, Viner RM, Booy R: Is it exposure to cigarette smoke or to smokers which increases the risk of meningococcal disease in teenagers?. Int J Epidemiol. 2006, 35: 330-336.View ArticlePubMedGoogle Scholar
- Al-Delaimy WK, Crane J, Woodward A: Passive smoking in children: effect of avoidance strategies, at home as measured by hair nicotine levels. Arch Environ Health. 2001, 56: 117-122. 10.1080/00039890109604062.View ArticlePubMedGoogle Scholar
- Giovino GA, Mirza SA, Samet JM, Gupta PC, Jarvis MJ, Bhala N, Peto R, Zatonski W, Hsia J, Morton J, Palipudi KM, Asma S, GATS Collaborative Group: Tobacco use in 3 billion individuals from 16 countries: an analysis of nationally representative cross-sectional household surveys. Lancet. 2012, 380: 668-679. 10.1016/S0140-6736(12)61085-X.View ArticlePubMedGoogle Scholar
- Advisory Committee on Immunization Practices: Recommended adult immunization schedule: United States, 2009*. Ann Intern Med. 2009, 150: 40-44.View ArticleGoogle Scholar
- Pilishvili T, Lexau C, Farley MM, Hadler J, Harrison LH, Bennett NM, Reingold A, Thomas A, Schaffner W, Craig AS, Smith PJ, Beall BW, Whitney CG, Moore MR, Active Bacterial Core Surveillance/Emerging Infections Program Network: Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. J Infect Dis. 2010, 201: 32-41. 10.1086/648593.View ArticlePubMedGoogle Scholar
- Terranella A, Cohn A, Clark T: Meningococcal conjugate vaccines: optimizing global impact. Infect Drug Resist. 2011, 4: 161-169.View ArticlePubMedPubMed CentralGoogle Scholar
- Kristiansen PA, Diomandé F, Ba AK, Sanou I, Ouédraogo AS, Ouédraogo R, Sangaré L, Kandolo D, Aké F, Saga IM, Clark TA, Misegades L, Martin SW, Thomas JD, Tiendrebeogo SR, Hassan-King M, Djingarey MH, Messonnier NE, Préziosi MP, Laforce FM, Caugant DA: Impact of the serogroup A meningococcal conjugate vaccine, MenAfriVac, on carriage and herd immunity. Clin Infect Dis. 2013, 56: 354-363. 10.1093/cid/cis892.View ArticlePubMedGoogle Scholar
- The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1741-7015/10/160/prepub
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