Bafeta A, Trinquart L, Seror R, Ravaud P: Analysis of the systematic reviews process in reports of network meta-analyses: methodological systematic review. BMJ. 2013, 347: f3675.
National Institute for Health and Care Excellence: Guide to the methods of technology appraisal. 2013, [http://publications.nice.org.uk/pmg9] Published 4 April 2013; Accessed 29 July 2013
Cooper NJ, Sutton AJ, Morris D, Ades AE, Welton NJ: Addressing between-study heterogeneity and inconsistency in mixed treatment comparisons: application to stroke prevention treatments in individuals with non-rheumatic atrial fibrillation. Stat Med. 2009, 28: 1861-1881.
Dias S, Sutton AJ, Ades AE, Welton NJ: Evidence synthesis for decision making 2: a generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials. Med Decis Making. 2013, 33: 607-617.
Jansen JP, Fleurence R, Devine B, Itzler R, Barrett A, Hawkins N, Lee K, Boersma C, Annemans L, Cappelleri J: Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: part 1. Value Health. 2011, 14: 429-437.
Jansen JP, Naci H: Is network meta-analysis as valid as standard pairwise meta-analysis? It all depends on the distribution of effect modifiers. BMC Med. 2013, 11: 159.
Gagnier JJ, Morgenstern H, Altman DG, Berlin J, Chang S, McCulloch P, Sun X, Moher D: Consensus-based recommendations for investigating clinical heterogeneity in systematic reviews. BMC Med Res Methodol. 2013, 13: 106.
Ades AE: A chain of evidence with mixed comparisons: models for multi-parameter synthesis and consistency of evidence. Stat Med. 2003, 22: 2995-3016.
Bucher HC, Guyatt GH, Griffith LE, Walter SD: The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials. J Clin Epidemiol. 1997, 50: 683-691.
Caldwell DM, Ades AE, Higgins JP: Simultaneous comparison of multiple treatments: combining direct and indirect evidence. BMJ. 2005, 331: 897-900.
Hoaglin DC, Hawkins N, Jansen JP, Scott DA, Itzler R, Cappelleri JC, Boersma C, Thompson D, Larholt KM, Diaz M, Barrett A: Conducting indirect-treatment-comparison and network-meta-analysis studies: report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: part 2. Value Health. 2011, 14: 429-437.
Lu G, Ades AE: Combination of direct and indirect evidence in mixed treatment comparisons. Stat Med. 2004, 23: 3105-3124.
Lumley T: Network meta-analysis for indirect treatment comparisons. Stat Med. 2002, 21: 2313-2324.
Salanti G, Higgins JPT, Ades AE, Ioannidis JPA: Evaluation of networks of randomized trials. Stat Methods Med Res. 2008, 17: 279-301.
Achana FA, Cooper NJ, Dias S, Lu G, Rice SJ, Kendrick D, Sutton AJ: Extending methods for investigating the relationship between treatment effect and baseline risk from pairwise meta-analysis to network meta-analysis. Stat Med. 2013, 32: 752-771.
Dias S, Welton NJ, Caldwell DM, Ades AE: Checking consistency in mixed treatment comparison meta-analysis. Stat Med. 2010, 29: 932-944.
Lu G, Ades AE: Assessing evidence inconsistency in mixed treatment comparisons. J Am Stat Assoc. 2006, 101: 447-4459.
White IF, Barrett JK, Jackson D, Higgens JP: Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression. Res Synth Meth. 2012, 3: 111-125.
Higgins JP, Jackson D, Barrett JK, Lu G, Ades AE, White IR: Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Meth. 2012, 3: 98-110.
Dias S, Sutton AJ, Welton NJ, Ades AE: Evidence synthesis for decision making 3: heterogeneity—subgroups, meta-regression, bias, and bias-adjustment. Med Decis Making. 2013, 33: 618.
Greenland S, Morgenstern H: Ecological bias, confounding, and effect modification. Int J Epidemiol. 1989, 18: 269-274.
Berlin JA, Santanna J, Schmid CH, Szczech LA, Fedlman HI, Anti-Lymphocyte Antibody Induction Therapy Study Group: Individual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head. Stat Med. 2002, 21: 371-387.
Afinitor Summary of Product Characteristics. [http://www.medicines.org.uk/emc/medicine/22281/SPC] Accessed 7 October 2013
Baselga J, Campone C, Piccart M, Burris HA, Rugo HS, Sahmoud T, Noguchi S, Gnant M, Pritchard KI, Lebrun F, Beck JT, Ito Y, Yardley D, Deleu I, Perez A, Bachelot T, Vittori L, Xu Z, Mukhopadhyay P, Lebwohl D, Hortobagyi GN: Everolimus in postmenopausal hormone-receptor–positive advanced breast cancer. N Engl J Med. 2012, 366: 520-529.
Beaver JA, Park BH: The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer. Future Oncol. 2012, 8: 651-657.
Piccart M, Noguchi S, Pritchard KI, Burris HA, Rugo HS, Gnant M, Hortobagyi GN, Melichar B, Petrakova K, Arena F, Xu C, Cahana A, Taran T, Sahmoud T, Lebwoh D, Campone M, Baselga J: Everolimus for postmenopausal women with advanced breast cancer: updated results of the BOLERO-2 Phase III Trial. J Clin Oncol. 2012, 30: suppl; abstr 559
Yardley DA, Noguchi S, Pritchard KI, Burris HA, Baselga J, Gnant M, Hortobagyi GN, Campone M, Pistilli B, Piccart M, Melichar B, Petrakova K, Arena FP, Erdkamp F, Harb WA, Feng W, Cahana A, Taran T, Lebwohl D, Rugo HS: Everolimus plus exemestane in postmenopausal patients with HR+ Breast Cancer: BOLERO-2 final progression-free survival analysis. Adv Ther. 2013, 30: 870-874.
Bachelot T, Bourgier C, Cropet C, Ray-Coquard I, Ferrero JM, Freyer G, Abadie-Lacourtoisie S, Eymard JC, Debled M, Spaeth D, Legouffe E, Allouache D, El Kouri C, Pujade-Lauraine E: Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study. J Clin Oncol. 2012, 30: 2718-2724.
National Institute for Health and Clinical Excellence: Early and Locally Advanced Breast Cancer Diagnosis and Treatment. NICE Clinical Guidelines, No. 80. 2009, Cardiff (UK): National Collaborating Centre for Cancer (UK), ISBN-13: 978-0-9558265-2-8. Available at: http://www.nice.org.uk/nicemedia/pdf/cg80niceguideline.pdf. Accessed 7 October 2013
National Institute for Health and Clinical Excellence: Everolimus in combination with exemestane for treating advanced HER2 negative hormone-receptor-positive breast cancer after endocrine therapy. Appraisal consultation document; March 2013. Available at: http://guidance.nice.org.uk/TAG/327/FAD. Accessed 7 October 2013
National Institute for Health and Clinical Excellence: Everolimus in combination with an aromatase inhibitor for the treatment of advanced or metastatic HER2 netative, oestrogen receptor positive breast cancer after prior endocrine therapy, Final scope. Single Technology Appraisal; October 2012. Available at: http://www.nice.org.uk/nicemedia/live/13866/61357/61357.pdf. Accessed 7 October 2013
Advanced Breast Cancer: Endocrine Therapy. [http://pathways.nice.org.uk/pathways/advanced-breast-cancer#path=view%3A/pathways/advanced-breast-cancer/advanced-breast-cancer-endocrine-therapy.xml&content=close]
Jansen JP, Cope S: Meta-regression models to address heterogeneity and inconsistency in network meta-analysis of survival outcomes. BMC Med Res Methodol. 2012, 12: 152.
Saad ED, Katz A: Progression-free survival and time to progression as primary end points in advanced breast cancer: often used, sometimes loosely defined. Ann Oncol. 2009, 20: 460-464.
Ouwens MJ, Philips Z, Jansen JP: Network meta-analysis of parametric survival curves. Res Synth Meth. 2011, 1: 258-271.
Jansen JP: Network meta-analysis of survival data with fractional polynomials. BMC Med Res Methodol. 2011, 11: 61.
Spiegelhalter DJ, Best NG, Carlin BP, van der Linde A: Bayesian measures of model complexity and fit. J R Stat Soc (Series B). 2002, 64: 583-639.
Dempster AP: The direct use of likelihood for significance testing. Stat Comput. 1997, 7: 247-252.
Cope S, Ouwens MJ, Jansen JP, Schmid P: Progression-free survival with fulvestrant 500 mg and alternative endocrine therapies as second-line treatment for advanced breast cancer: a network meta-analysis with parametric survival models. Value Health. 2013, 16: 403-417.
A randomized trial in postmenopausal patients with advanced breast cancer comparing endocrine and cytotoxic therapy given sequentially or in combination. The Australian and New Zealand Breast Cancer Trials Group, Clinical Oncological Society of Australia. J Clin Oncol. 1986, 4: 186-193.
Beuselinck B, Wildiers H, Wynendaele W, Dirix L, Kains JP, Paridaens R: Weekly paclitaxel versus weekly docetaxel in elderly or frail patients with metastatic breast carcinoma: a randomized phase-II study of the Belgian Society of Medical Oncology. Crit Rev Oncol Hematol. 2010, 75: 70-77.
Bontenbal M, Andersson M, Wildiers J, Cocconi G, Jassem J, Paridaens R, Rotmensz N, Sylvester R, Mouridsen HT, Klijn JG, van Oosterom AT: Doxorubicin vs. epirubicin, report of a second-line randomized phase II/III study in advanced breast cancer. EORTC Breast Cancer Cooperative Group. Br J Cancer. 1998, 77: 2257-2263.
Dixon AR, Jackson L, Chan S, Haybittle J, Blamey RW: A randomised trial of second-line hormone vs single agent chemotherapy in tamoxifen resistant advanced breast cancer. Br J Cancer. 1992, 66: 402-404.
Gill PG, Gebski V, Snyder R, Burns I, Levi J, Byrne M, Coates A: Randomized comparison of the effects of tamoxifen, megestrol acetate, or tamoxifen plus megestrol acetate on treatment response and survival in patients with metastatic breast cancer. Ann Oncol. 1993, 4: 741-744.
Gradishar WJ, Krasnojon D, Cheporov S, Makhson AN, Manikhas GM, Clawson A, Bhar P: Significantly longer progression-free survival with nab-paclitaxel compared with docetaxel as first-line therapy for metastatic breast cancer. J Clin Oncol. 2009, 27: 3611-3619.
Gradishar WJ, Krasnojon D, Cheporov S, Makhson AN, Manikhas GM, Clawson A, Bhar P, McGuire JR, Iglesias J: Phase II trial of nab-paclitaxel compared with docetaxel as first-line chemotherapy in patients with metastatic breast cancer: final analysis of overall survival. Clin Breast Cancer. 2012, 12: 313-321.
Henderson IC, Allegra JC, Woodcock T, Wolff S, Bryan S, Cartwright K, Dukart G, Henry D: Randomized clinical trial comparing mitoxantrone with doxorubicin in previously treated patients with metastatic breast cancer. J Clin Oncol. 1989, 7: 560-571.
Ingle JN, Ahmann DL, Green SJ, Edmonson JH, Creagan ET, Hahn RG, Rubin J: Randomized clinical trial of megestrol acetate versus tamoxifen in paramenopausal or castrated women with advanced breast cancer. Am J Clin Oncol. 1982, 5: 155-160.
Jones SE, Erban J, Overmoyer B, Budd GT, Hutchins L, Lower E, Laufman L, Sundaram S, Urba WJ, Pritchard KI, Mennel R, Richards D, Olsen S, Meyers ML, Ravdin PM: Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J Clin Oncol. 2005, 23: 5542-5551.
Katsumata N, Watanabe T, Minami H, Aogi K, Tabei T, Sano M, Masuda N, Andoh J, Ikeda T, Shibata T, Takashima S: Phase III trial of doxorubicin plus cyclophosphamide (AC), docetaxel, and alternating AC and docetaxel as front-line chemotherapy for metastatic breast cancer: Japan clinical oncology group trial (JCOG9802). Ann Oncol. 2009, 20: 1210-1215.
Kaufmann M, Bajetta E, Dirix LY, Fein LE, Jones SE, Zilembo N, Dugardyn JL, Nasurdi C, Mennel RG, Cervek J, Fowst C, Polli A, di Salle E, Arkhipov A, Piscitelli G, Miller LL, Massimini G: Exemestane is superior to megestrol acetate after tamoxifen failure in postmenopausal women with advanced breast cancer: results of a phase III randomized double-blind trial. J Clin Oncol. 2000, 18: 1399-1411.
Kaufmann M, Bajetta E, Dirix LY, Fein LE, Jones SE, Zilembo N, Dugardyn JL, Nasurdi C, Mennel RG, Cervek J, Fowst C, Polli A, di Salle E, Arkhipov A, Piscitelli G, Miller LL, Massimini G: Exemestane improves survival in metastatic breast cancer: results of a phase III randomized study. Clin Breast Cancer. 2000, S15-S18.
Kaufmann M, Bajetta E, Dirix LY, Fein LE, Jones SE, Cervek J, Fowst C, Polli A, Di Salle E, Massimini G, Piscitelli G: Exemestane improves survival compared with megoestrol acetate in postmenopausal patients with advanced breast cancer who have failed on tamoxifen: results of a double-blind randomised phase III trial. Eur J Cancer. 2000, 36: S86-S87.
Meier CR, Illiger HJ, Steder M, Janssen J, Deertz H, Braun M, Oeney HT, Deuss B, Kuchler T, Rotermund S: Weekly vinorelbine versus docetaxel for metastatic breast cancer after failing anthracycline treatment. Onkologie. 2008, 31: 447-453.
Muss HB, Paschold EH, Black WR, Cooper MR, Capizzi RL, Christian R, Cruz JM, Jackson DV, Stuart JJ, Richards F, White DR, Zekan PJ, Spurr CL, Pope E, Cose D, Morgan T, Wells HB: Megestrol acetate v tamoxifen in advanced breast cancer: a phase III trial of the Piedmont Oncology Association (POA). Semin Oncol. 1985, 12: 55-61.
Muss HB, Wells HB, Paschold EH, Black WR, Cooper MR, Capizzi RL, Christian R, Cruz JM, Jackson DV, Powell BL: Megestrol acetate versus tamoxifen in advanced breast cancer: 5-year analysis–a phase III trial of the Piedmont Oncology Association. J Clin Oncol. 1988, 6: 1098-1106.
O'Brien ME, Wigler N, Inbar M, Rosso R, Grischke E, Santoro A, Catane R, Kieback DG, Tomczak P, Ackland SP, Orlandi F, Mellars L, Alland L, Tendler C: Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer. Ann Oncol. 2004, 15: 440-449.
O'Shaughnessy JA, Blum J, Moiseyenko V, Jones SE, Miles D, Bell D, Rosso R, Mauriac L, Osterwalder B, Burger HU, Laws S: Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancer. Ann Oncol. 2001, 12: 1247-1254.
Paridaens R, Biganzoli L, Bruning P, Klijn JG, Gamucci T, Houston S, Coleman R, Schachter J, Van Vreckem A, Sylvester R, Awada A, Wildiers J, Piccart M: Paclitaxel versus doxorubicin as first-line single-agent chemotherapy for metastatic breast cancer: a European Organization for Research and Treatment of Cancer Randomized Study with cross-over. J Clin Oncol. 2000, 18: 724-733.
Paridaens R, Dirix L, Beex L, Nooij M, Cufer T, Lohrisch C, Biganzoli L, Hoorebeeck I, Duchateau L, Lobelle JP, Piccart M: Promising results with exemestane in the first-line treatment of metastatic breast cancer: a randomized phase II EORTC trial with a tamoxifen control. Clin Breast Cancer. 2000, S19-S21.
Paridaens R, Dirix L, Beex L, Nooij M, Cufer T, Lohrisch C, Biganzoli L, Hoorebeeck I, Duchateau L, Lobelle JP, Piccart M: Mature results of a randomized phase II multicenter study of exemestane versus tamoxifen as first-line hormone therapy for postmenopausal women with metastatic breast cancer. Ann Oncol. 2003, 14: 1391-1398.
Paridaens RJ, Dirix LY, Beex LV, Nooij M, Cameron DA, Cufer T, Piccart MJ, Bogaerts J, Therasse P: Phase III study comparing exemestane with tamoxifen as first-line hormonal treatment of metastatic breast cancer in postmenopausal women: the European Organisation for Research and Treatment of Cancer Breast Cancer Cooperative Group. J Clin Oncol. 2008, 26: 4883-4890.
Sledge GW, Neuberg D, Bernardo P, Ingle JN, Martino S, Rowinsky EK, Wood WC: Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (E1193). J Clin Oncol. 2003, 21: 588-592.
Villalon AH, Ngelangel CA, Eufemio G, Laudico AV: Cyclophosphamide methotrexate 5-fluorouracil (CMF), vs. CMF megestrol acetate (CMF-M), vs. Megestrol acetate (M) for advanced breast cancer in Filipino women. Philipp J Intern Med. 1993, 31: 115-126.
Chan S, Friedrich K, Noel D, Pinter T, Van Belle S, Vorobiof D, Duarte R, Gil Gil M, Bodrogi I, Murray E, Yelle L, von Minckwitz G, Korec S, Simmonds P, Buzzi F, Mancha RG, Richardson G, Walpole E, Ronzoni M, Murawsky M, Alakl M, Riva A, Crown J: Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J Clin Oncol. 1999, 17: 2341-2354.
Yardley DA, Burris HA, Spigel DR, Clark BL, Vazquez E, Shipley D, Barton J, Thompson D, Montes I, Greco FA, Hainsworth JD: A phase II randomized crossover study of liposomal doxorubicin versus weekly docetaxel in the first-line treatment of women with metastatic breast cancer. Clin Breast Cancer. 2009, 9: 247-252.
Cooper NJ, Peters J, Lai MC, Juni P, Wandel S, Palmer S, Paulden M, Conti S, Welton NJ, Abrams KR, Bujkiewicz S, Spiegelhalter D, Sutton AJ: How valuable are multiple treatment comparison methods in evidence-based health-care evaluation?. Value Health. 2011, 14: 371-380.
Cowan JD, Neidhart J, McClure S, Coltman CA, Gumbart C, Martino S, Hutchins LF, Stephens RL, Vaughan CB, Osborne CK: Randomized trial of doxorubicin, bisantrene and mitoxantrone in advanced breast cancer: a Southwest Oncology Group Study. J Natl Cancer Inst. 1991, 83: 1077-1084.
Cope S, Jansen JP: Quantitative summaries of treatment effect estimates obtained with network meta-analysis of survival curves to inform decision-making. BMC Med Res Methodol. 2013, 13: 147.
Jansen JP, Trikalinos T, Cappelleri JC, Daw J, Andes S, Eldessouki R, Salanti G: Indirect treatment comparison/ network meta-analysis study questionnaire to assess relevance and credibility to inform health care decision-making: an ISPOR-AMCP-NPC good practice task force report. Value Health. 2014, 17: 157-73.
Ades AE, Caldwell DM, Reken S, Welton NJ, Sutton AJ, Dias S: Evidence synthesis for decision making 7: a reviewer’s checklist. Med Decis Making. 2013, 33: 679-691.
Mills EJ, Ioannidis JP, Thorlund K, Schünemann HJ, Puhan MA, Guyatt GH: How to use an article reporting a multiple treatment comparison meta-analysis. JAMA. 2012, 308: 1246-1253.
Fleeman N, Bagust A, Beale S, Blundell M, Dwan K, Pilkington G, Proudlove C, Dundar Y, Vecchio F, Thorp N: Everolimus in combination with an aromatase inhibitor for the treatment of breast cancer after prior endocrine therapy: a single technology appraisal. LRiG, The University of Liverpool. 2013, [http://www.nice.org.uk/nicemedia/live/13866/63219/63219.pdf] Accessed 7 Oct 2013
Bachelot T, McCool R, Duffy S, Glanville J, Varley D, Fleetwood K, Zhang J, Jerusalem G: Comparative efficacy of everolimus plus exemestane versus fulvestrant for hormone-receptor-positive advanced breast cancer following progression/recurrence after endocrine therapy: a network meta-analysis. Breast Cancer Res Treat. 2014, 143: 125-133.
Spineli LM, Higgins JP, Cipriani A, Leucht S, Salanti G: Evaluating the impact of imputations for missing participant outcome data in a network meta-analysis. Clin Trials. 2013, 10: 378-388.
Cope S, Capkun-Niggli G, Gale R, Lassen C, Owen R, Ouwens MJ, Bergman G, Jansen JP: Efficacy of once-daily indacaterol relative to alternative bronchodilators in COPD: a patient-level mixed treatment comparison. Value Health. 2012, 15: 524-533.
Donegan S, Williamson P, D'Alessandro U, Tudur Smith C: Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates. Stat Med. 2012, 31: 3840-3857.
Saramago P, Sutton AJ, Cooper NJ, Manca A: Mixed treatment comparisons using aggregate and individual participant level data. Stat Med. 2012, 31: 3516-3536.
McCarron CE, Pullenayegum EM, Thabane L, Goeree R, Tarride JE: Bayesian hierarchical models combining different study types and adjusting for covariate imbalances: a simulation study to assess model performance. PLoS One. 2011, 6: e25635.
McCarron CE, Pullenayegum EM, Thabane L, Goeree R, Tarride JE: The impact of using informative priors in a Bayesian cost-effectiveness analysis: an application of endovascular versus open surgical repair for abdominal aortic aneurysms in high-risk patients. Med Decis Making. 2013, 33: 437-450.
Schmitz S, Adams R, Walsh C: Incorporating data from various trial designs into a mixed treatment comparison model. Stat Med. 2013, 32: 2935-2949.
Turner RM, Spiegelhalter DJ, Smith GC, Thompson SG: Bias modelling in evidence synthesis. J R Stat Soc Ser A. 2009, 172: 21-47.