Skip to main content
Figure 1 | BMC Medicine

Figure 1

From: Differential endothelial cell gene expression by African Americans versusCaucasian Americans: a possible contribution to health disparity in vascular disease and cancer

Figure 1

BOEC expression of PSPH , authentic-PSP ( PSPH ), and PSH-homolog ( PSPHL ). PSPH is the proper gene designation for the L-phosphoserine-phosphatase gene. Its expression per the Affymetrix U133A chip (probest 205048_s_at) seems to show elevation for AA (panel A). However, when authentic PSPH is measured by qRT-PCR, no difference for between groups is found (panel B). Rather, the elevation detected by microarray (panel A) is fully accounted for by increased expression (P = .015) of the PSP-homolog, PSPHL, in AA >CA (panel C). By qRT-PCR, expression of PSH for 1/21 AA and for 12/17 CA samples was undetectable.

Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us