Skip to main content

Table 3 Accuracy characteristics of microRNAs in discriminating metastatic and non-metastatic lymph nodes in FFPE and FNA biopsies from lymph node samples

From: Erratum: Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma

microRNA PPV NPV Accuracy AUC (95 % CI)
% (95 % CI) % (95 % CI) % (95 % CI)
FFPE samples
 miR-200a 100 (82.2-100.0) 68.4 (43.5-87.3) 84.2 (68.1-93.4) 0.92 (0.83-0.99)
 miR-200c 100 (84.4-100.0) 81.2 (54.34-95.73) 92.1 (77.5-97.9) 0.94 (0.85-1.0)
 miR-203 100 (86.2-100) 100 (75.1-100) 100 (88.6-100) 1.0 (0–1.0)
 miR-205 100 (86.2-100) 100 (75.1-100) 100 (88.6-100) 1.0 (0–1.0)
FNA samples classified by cytology
 miR-203 100 (91.5-100) 100 (94.9-100) 100 (96.05-100) 1.0 (0–1.0)
 miR-205 100 (91.5-100) 100 (94.9-100) 100 (96.05-100) 1.0 (0–1.0)
FNA samples classified by histology
 miR-203 100 (90.9-100) 95.9 (88.6-99.1) 97.3 (92.1-99.4) 0.963 (0.921-1.0)
 miR-205 100 (93.2-100) 94.6 (85.1-98.8) 96.7 (93.1-100) 0.966 (0.921-1.0)
  1. FFPE, formalin-fixed paraffin embedded; FNA, fine-needle aspiration; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the ROC curve; CI, confidence interval
\