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Table 1 Clinical and biological characteristics of patients with non-alcoholic steatohepatitis for antibody measurements

From: Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease

  Participant characteristics (mean ± SD)
  Controls
(n = 68)
NAFLD
(simple steatosis) (n = 18)
NAFLD
(NASH) (n = 53)
Male/female 27/41 9/9 24/29
Age (y) 40.9 ± 12 45.7 ± 13 45.9 ± 10
BMI (kg/m2) 26.3 ± 4.9 33.6 ± 5.6 34.3 ± 4.7
Waist circumference (cm) 89.4 ± 13.7 108.5 ± 12.9 109.0 ± 14.3
Triglycerides (mg/dL)   
Median 75 151 160
Interquartile range 48 66 118.5
Cholesterol (mg/dL) 181.33 ± 32.9 197.8 ± 53.2 196.2 ± 43.5
HDL (mg/dL) 54.8 ± 17.7 41.44 ± 8.0 42.87 ± 8.9
LDL (mg/dL) 105.65 ± 26.9 135.3 ± 47.2 122.9 ± 36.3
  Markers of inflammation and liver blood tests (mean (IQR))
TNF-α (pg/ml) 2.5 (0.7) 3 (2.3) 3 (1.9)
MCP-1 (pg/ml) 96.9 (27) 122.4 (24.05) 120.1 (37.95)
IL-1β (pg/ml) 0.42 (0.87) 0.27 (0.36) 0.17 (0.64)
IL-6 (pg/ml) 13.2 (35.8) 16.1 (8.1) 24.5 (45.25)
IL-8 (pg/ml) 5.4 (4) 5.34 (3.5) 7.7 (8.05)
γGT (IU/L) - 51.6 (22.7) 55.6 (32)
Leptin 11.1 (8.8) 23.0 (15.8) 30.5 (18.5)
AST (IU/L) 21 (9) 28 (11.8) 49 (56.5)
ALT (IU/L) 18 (8) 38 (22.8) 66 (99.5)
AST/ALT ratio 1.3 (0.25) 0.8 (0.2) 0.8 (0.4)
  1. AST aspartate transaminase, ALT alanine transaminase, BMI body mass index, γGT gamma-glutamyltransferase, HDL high-density lipoprotein, IL interleukin, IQR interquartile range, LDL low-density lipoprotein, MCP-1 monocyte chemoattractant protein-1, NAFLD non-alcoholic fatty liver disease, NASH non-alcoholic steatohepatitis, TNF-α tumor necrosis factor alpha