Kohavi R. Online Controlled Experiments. KDD '15. New York, NY: ACM Press; 2015. http://www.exp-platform.com/Pages/KDD2015KeynoteExPKohavi.aspx. Accessed 24 Oct 2016
Morgan S, Grootendorst P, Lexchin J, Cunningham C, Greyson D. The cost of drug development: a systematic review. Health Policy. 2011;100:4–17.
Article
PubMed
Google Scholar
Henrich J, Heine SJ, Norenzayan A. The weirdest people in the world? Behav Brain Sci. 2010;33:61–83. Discussion 83–135.
Article
PubMed
Google Scholar
Greenhalgh T, Howick J, Maskrey N, Evidence Based Medicine Renaissance Group. Evidence based medicine: a movement in crisis? BMJ. 2014;348:g3725–5.
Article
PubMed
PubMed Central
Google Scholar
Morgan S, Daw J, Thomson P. International best practices for negotiating “reimbursement contracts” with price rebates from pharmaceutical companies. Health Aff (Millwood). 2013;32:771–7.
Article
Google Scholar
Deeny SR, Steventon A. Making sense of the shadows: priorities for creating a learning healthcare system based on routinely collected data. BMJ Qual Saf. 2015;24:505–15.
Article
PubMed
PubMed Central
Google Scholar
Neumann PG. Automated Car Woes---Whoa There! ACM Ubiquity. 2016;2016:1. doi:10.1145/2974062.
Article
Google Scholar
Omer T. Empowered citizen health hackers who are not waiting. BMC Med. 2016;14:118.
Article
PubMed
PubMed Central
Google Scholar
Hibbard JH, Mahoney ER, Stock R, Tusler M. Do increases in patient activation result in improved self‐management behaviors? Health Serv Res. 2007;42:1443–63.
Article
PubMed
PubMed Central
Google Scholar
Weber GM, Mandl KD, Kohane IS. Finding the missing link for big biomedical data. JAMA. 2014;311(24):2479–80.
CAS
PubMed
Google Scholar
Lee JM, Hirschfeld E, Wedding J. A patient-designed do-it-yourself mobile technology system for diabetes: promise and challenges for a new era in medicine. JAMA. 2016;315:1447–8.
Article
CAS
PubMed
Google Scholar
Alper BS, Hand JA, Elliott SG, Kinkade S, Hauan MJ, Onion DK, et al. How much effort is needed to keep up with the literature relevant for primary care? J Med Libr Assoc. 2004;92:429–37.
PubMed
PubMed Central
Google Scholar
Tresp V, Overhage M, Bundschus M, Rabizadeh S, Fasching P, Yu S. Going digital: a survey on digitalization and large scale data analytics in healthcare. arXiv preprint arXiv:1606.08075. 2016. https://arxiv.org/abs/1606.08075. Accessed 24 Oct 2016
Wicks P, Chiauzzi E. “Trust but verify--” five approaches to ensure safe medical apps. BMC Med. 2015;13:205.
Article
PubMed
PubMed Central
Google Scholar
Goldacre B. Bad pharma: how drug companies mislead doctors and harm patients. London: Fourth Estate; 2012.
Google Scholar
Hawkes N. NHS data sharing deal with Google prompts concern. BMJ. 2016;353:i2573.
Article
PubMed
Google Scholar
Baldassano S, Wulsin D, Ung H, Blevins T, Brown M-G, Fox E, et al. A novel seizure detection algorithm informed by hidden Markov model event states. J Neural Eng. 2016;13:036011.
Article
PubMed
Google Scholar
Min S, Lee B, Yoon S. Deep learning in bioinformatics. arXiv:1603.06430. 2016. https://arxiv.org/abs/1603.06430. Accessed 24 Oct 2016
Office for National Statistics. Mortality in the United Kingdon 1983–2013. 2014. http://www.ons.gov.uk/ons/rel/mortality-ageing/mortality-in-the-united-kingdom/1983-2013/index.html. Accessed 24 Oct 2016
Vos T, Barber RM, Bell B, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.
Article
Google Scholar
Chisholm D, Sweeny K, Sheehan P, et al. Scaling-up treatment of depression and anxiety: a global return on investment analysis. Lancet Psychiatry. 2016;3(5):415–24.
Article
PubMed
Google Scholar
Hotopf M, McCracken L. Physical health and mental illness. In: Mehta N, editor. Annual Report of the Chief Medical Officer 2013. London: Department of Health; 2014.
Google Scholar
Cook MJ, O'Brien TJ, Berkovic SF, et al. Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study. Lancet Neurol. 2013;12(6):563–71.
Article
PubMed
Google Scholar
Narayan VA, Mohwinckel M, Pisano G, Yang M, Manji HK. Beyond magic bullets: true innovation in health care. Nat Rev Drug Discov. 2013;12(2):85–6.
Article
CAS
PubMed
Google Scholar
GSMA The Mobile Economy 2015. www.gsma.com/mobileeconomy/global/2015/. Accessed 24 Oct 2016
Jackson A, Cavanagh J, Scott J. A systematic review of manic and depressive prodromes. J Affect Disord. 2003;74(3):209–17.
Article
PubMed
Google Scholar
Saeb S, Zhang M, Karr CJ, et al. Mobile phone sensor correlates of depressive symptom severity in daily-life behavior: an exploratory study. J Med Internet Res. 2015;17(7):e175.
Article
PubMed
PubMed Central
Google Scholar
Innovative Medicines Initiative. RADAR-CNS Remote Assessment of Disease and Relapse in Central Nervous System Disorders. https://www.imi.europa.eu/content/radar-cns. Accessed 24 Oct 2016
Snyder CF, Aaronson NK, Choucair AK, Elliott TE, Greenhalgh J, Halyard MY, Hess R, Miller DM, Reeve BB, Santana M. Implementing patient-reported outcomes assessment in clinical practice: a review of the options and considerations. Qual Life Res. 2012;21(8):1305–14.
Article
PubMed
Google Scholar
Kotronoulas G, Kearney N, Maguire R, Harrow A, Di Domenico D, Croy S, Macgillivray S. What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials. J Clin Oncol. 2014;32(14):1480–501.
Article
PubMed
Google Scholar
Vickers AJ, Salz T, Basch E, Cooperberg MR, Carroll PR, Tighe F, Eastham J, Rosen RC. Electronic patient self-assessment and management (SAM): a novel framework for cancer survivorship. BMC Med Inform Decis Mak. 2010;10:34.
Article
PubMed
PubMed Central
Google Scholar
Basch E, Deal AM, Kris MG, Scher HI, Hudis CA, Sabbatini P, Rogak L, Bennett AV, Dueck AC, Atkinson TM, Chou JF, Dulko D, Sit L, Barz A, Novotny P, Fruscione M, Sloan JA, Schrag D. Symptom monitoring with patient-reported outcomes during routine cancer treatment: a randomized controlled trial. J Clin Oncol. 2016;34(6):557–65.
Article
CAS
PubMed
Google Scholar
Wu AW, Kharrazi H, Boulware LE, Snyder CF. Measure once, cut twice—adding patient-reported outcome measures to the electronic health record for comparative effectiveness research. J Clin Epidemiol. 2013;66(8 Suppl):S12–20.
Article
PubMed
PubMed Central
Google Scholar
National Quality Forum. Patient-reported outcomes (PROs) in performance measurement. 2013. www.qualityforum.org/Projects/n-r/Patient-Reported_Outcomes/Patient-Reported_Outcomes.aspx. Accessed 24 Oct 2016
Basch E, Spertus J, Dudley RA, Wu A, Chuahan C, Cohen P, Smith ML, Black N, Crawford A, Christensen K, Blake K, Goertz C. Methods for developing patient-reported outcome-based performance measures (PRO-PMs). Value Health. 2015;18(4):493–504.
Article
PubMed
Google Scholar
Jensen RE, Snyder CF, Basch E, Frank L, Wu AW. All together now: findings from a PCORI workshop to align patient-reported outcomes in the electronic health record. J Comp Eff Res. 2016;5(6):561–7.
Article
PubMed
Google Scholar
Methodology Committee of the Patient-Centered Outcomes Research Institute (PCORI). Methodological standards and patient-centeredness in comparative effectiveness research: the PCORI perspective. JAMA. 2012;307(15):1636–40.
Article
Google Scholar
Basch E, Torda P, Adams K. Standards for patient-reported outcome-based performance measures. JAMA. 2013;310(2):139–40.
Article
CAS
PubMed
Google Scholar
Vickers AJ. Clinical trials in crisis: four simple methodologic fixes. Clin Trials. 2014;11(6):615–21.
Article
PubMed
PubMed Central
Google Scholar
Wicks P, Vaughan T, Heywood J. Subjects no more: what happens when trial participants realize they hold the power? BMJ. 2014;348:g368.
Article
PubMed
PubMed Central
Google Scholar
Bucci S, Barrowclough C, Ainsworth J, Morris R, Berry K, Machin M, et al. Using mobile technology to deliver a cognitive behavior therapy-informed intervention in early psychosis (Actissist): study protocol for a randomized controlled trial. Trials. 2015;16:404.
Article
PubMed
PubMed Central
Google Scholar
AllTrials. http://www.alltrials.net. 2016. Accessed 17 Aug 2016.
Bierer B, Li R, Barnes M, Sim I. A global neutral platform for sharing trial data. N Engl J Med. 2016;374:2411–3.
Article
PubMed
Google Scholar
Fraccaro P, Dentone C, Fenoglio D, Giacomini M. Multicentre clinical trials data management: a hybrid solution to exploit the strengths of electronic data capture and electronic health records systems. Inform Health Soc Care. 2013;38(4):313–29.
Article
PubMed
Google Scholar
Woodcock A, Bakerly ND, New JP, Gibson JM, Wu W, Vestbo J, Leather D. The Salford Lung Study protocol: a pragmatic, randomized phase III real-world effectiveness trial in asthma. BMC Pulm Med. 2015;15:160.
Article
PubMed
PubMed Central
Google Scholar
Icahn School of Medicine: Asthma mobile health study. 2016. http://apps.icahn.mssm.edu/asthma. Accessed 17 Aug 2016.
Apple Research Kit. 2016. http://www.apple.com/researchkit. Accessed 17 Aug 2016.
Tahir D. New app aids Mount Sinai asthma research. Modern Healthcare. 2015. http://www.modernhealthcare.com/article/20150321/MAGAZINE/303219927. Accessed 17 Aug 2016
Williams H, Spencer K, Sanders C, Lund D, Whitley EA, Kaye J, Dixon WG. Dynamic consent: a possible solution to improve patient confidence and trust in how electronic patient records are used in medical research. JMIR Med Inform. 2015;3(1):e3.
Article
PubMed
PubMed Central
Google Scholar
NHS Atlases of Variation. http://www.rightcare.nhs.uk/atlas/2015_IAb/atlas.html. Accessed 10 Oct 2015.
Gray M. How to Get Better Value Healthcare. 2nd edition. Oxford: Offox Press Ltd.; 2011.
Academy of Medical Royal Colleges report on Protecting Resources, Promoting Value. http://www.aomrc.org.uk/wp-content/uploads/2016/05/Protecting_Resources_Promoting_Value_1114.pdf. Accessed 10 Oct 2015.
Donabedian A. Evaluating the quality of medical care. Milbank Q. 1966;44(3 Pt. 2):166–203.
Article
Google Scholar