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Fig. 2 | BMC Medicine

Fig. 2

From: Towards the concept of disease-modifier in post-stroke or vascular cognitive impairment: a consensus report

Fig. 2

Interactions between pre- and post-stroke cognitive disorders and dementia. Pre-stroke dementia may be related to vascular or degenerative processes, indicating that cognitive impairment after a stroke can be associated with a pure vascular mechanism or a mixed process. Stroke induces regional atrophy through neuronal death directly related to the vascular lesion, or indirectly to the Alzheimer’s disease (AD)-related pathway

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