Tian H, Liu Y, Li Y, Wu C-H, Chen B, Kraemer MU, Li B, Cai J, Xu B, Yang Q, et al. An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China. Science. 2020;368(6491):638-42.
Kraemer MU, Yang C-H, Gutierrez B, Wu C-H, Klein B, Pigott DM, du Plessis L, Faria NR, Li R, Hanage WP, et al. The effect of human mobility and control measures on the COVID-19 epidemic in China. Science. 2020;368(6490):493-97.
Hellewell J, Abbott S, Gimma A, Bosse NI, Jarvis CI, Russell TW, Munday JD, Kucharski AJ, Edmunds WJ, Sun F, et al. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. Lancet Glob Health. 2020;8(4):e488-96.
Gandhi M, Yokoe DS, Havlir DV. Asymptomatic transmission, the Achilles’ heel of current strategies to control Covid-19. N Engl J Med. 2020. https://doi.org/10.1056/NEJMe2009758.
Ganyani T, Kremer C, Chen D, Torneri A, Faes C, Wallinga J, Hens N. Estimating the generation interval for coronavirus disease (COVID-19) based on symptom onset data, March 2020. Eurosurveillance. 2020;25(17).
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, et al. Therapeutic efficacy of the small molecule gs-5734 against Ebola virus in rhesus monkeys. Nature. 2016;531(7594):381–5.
Article
CAS
Google Scholar
Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, Shi Z, Hu Z, Zhong W, Xiao G. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-ncov) in vitro. Cell Res. 2020;30(3):269–71.
Article
CAS
Google Scholar
Sheahan, T.P., Sims, A.C., Leist, S.R., Sch¨afer, A., Won, J., Brown, A.J., Montgomery, S.A., Hogg, A., Babusis, D., Clarke, M.O., Spahn, J.E., Bauer, L., Sellers, S., Porter, D., Feng, J.Y., Cihlar, T., Jordan, R., Denison, M.R., Baric, R.S.: Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against mers-cov. Nature Communications 11(1), 222 (2020).
Rhodes PH, Halloran ME, Longini IM Jr. Counting process models for infectious disease data: distinguishing exposure to infection from susceptibility. J R Stat Soc Ser B Methodol. 1996;58(4):751–62.
Google Scholar
Svensson °A. A note on generation times in epidemic models. Mathematical biosciences. 2007;208(1):300–11.
Zhang J, Litvinova M, Wang W, Wang Y, Deng X, Chen X, Li M, Zheng W, Yi L, Chen X, Wu Q, Liang Y, Wang X, Yang J, Sun K, Longini IM, Halloran ME, Wu P, Cowling BJ, Merler S, Viboud C, Vespignani A, Ajelli M, Yu H. Evolving epidemiology of novel coronavirus diseases 2019 and possible interruption of local transmission outside Hubei province in China: a descriptive and modeling study. The Lancet Infectious Diseases. 2020. https://doi.org/10.1016/S1473-3099(20)30230-9.
Li Q, Guan X, Wu, P, Wang X, Zhou L, Tong Y, Ren R, Leung KSM, Lau EHY, Wong JY, Xing X, Xiang N, Wu Y, Li C, Chen Q, Li D, Liu T, Zhao J, Liu M, Tu W, Chen C, Jin L, Yang R, Wang Q, Zhou S, Wang R, Liu H, Luo Y, Liu Y, Shao G, Li H, Tao Z, Yang Y, Deng Z, Liu B, Ma Z, Zhang Y, Shi G, Lam TTY, Wu JT, Gao GF, Cowling BJ, Yang B, Leung GM, Feng Z. Early transmission dynamics in Wuhan, China, of Novel Coronavirus - Infected Pneumonia. New England J Med. 2020;382(13):1199-207.
Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, Yu J, Kang M, Song Y, Xia J, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med. 2020;382(12):1177-9.
Donnelly CA, Ghani AC, Leung GM, Hedley AJ, Fraser C, Riley S, Abu-Raddad LJ, Ho L-M, Thach T-Q, Chau P, Chan K-P, Lam T-H, Tse L-Y, Tsang T, Liu S-H, Kong JH, Lau EM, Ferguson NM, Anderson RM. Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. Lancet. 2003;361(9371):1761–6.
Article
Google Scholar
Flahault A. Has China faced only a herald wave of SARS-CoV-2? The Lancet. 2020;395(10228):947.
World Health Organization: Coronavirus disease 2019 - (COVID19). situation report - 46. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200306-sitrep-46-covid-19.pdf?sfvrsn=96b04adf2
.
Li R, Pei S, Chen B, Song Y, Zhang T, Yang W, Shaman J. Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2). Science. 2020;368(6490):489-93.
Nishiura H, Kobayashi T, Suzuki A, Katsuma Hayashi S-MJ, Kinoshita R, Yang Y, Yuan B, Akhmetzhanov AR, Linton NM. Estimation of the asymptomatic ratio of novel coronavirus infections (covid-19). Int J Infect Dis. 2020.
Guan, W.-j., Ni, Z.-y., Hu, Y., Liang, W.-h., Ou, C.-q., He, J.-x., Liu, L., Shan, H., Lei, C.-l., Hui, D.S.C., Du, B., Li, L.-j., Zeng, G., Yuen, K.-Y., Chen, R.-c., Tang, C.-l., Wang, T., Chen, P.-y., Xiang, J., Li, S.-y., Wang, J.-l., Liang, Z.-j., Peng, Y.-x., Wei, L., Liu, Y., Hu, Y.-h., Peng, P., Wang, J.-m., Liu, J.-y., Chen, Z., Li, G., Zheng, Z.-j., Qiu, S.-q., Luo, J., Ye, C.-j., Zhu, S.-y., Zhong, N.-s.: Clinical characteristics of coronavirus disease 2019 in china. New England J Med 2020. https://doi.org/10.1056/NEJMoa2002032.
Willem L, Hoang TV, Funk S, Coletti P, Beutels P, Hens N. Socrates: An online tool leveraging a social contact data sharing initiative to assess mitigation strategies for covid-19. medRxiv. 2020. https://doi.org/10.1101/2020.03.03.20030627.
Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, Si H-R, Zhu Y, Li B, Huang C-L, Chen H-D, Chen J, Luo Y, Guo H, Jiang R-D, Liu M-Q, Chen Y, Shen X-R, Wang X, Zheng X-S, Zhao K, Chen Q-J, Deng F, Liu L-L, Yan B, Zhan F-X, Wang Y-Y, Xiao G-F, Shi Z-L. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020. https://doi.org/10.1038/s41586-0202012-7.
Pan Y, Zhang D, Yang P, Poon LLM, Wang Q. Viral load of SARS-CoV-2 in clinical samples. The Lancet Infectious Diseases. 2020;20(4):411-2.
Linton N, Kobayashi T, Yang Y, Hayashi K, Akhmetzhanov A, Jung S-M, Yuan B, Kinoshita R, Nishiura H. Incubation period and other epidemiological characteristics of 2019 novel coronavirus infections with right truncation: a statistical analysis of publicly available case data. J Clin Med. 2020;9(2):538.
Article
Google Scholar
Bonhoeffer S, May RM, Shaw GM, Nowak MA. Virus dynamics and drug therapy. Proc Natl Acad Sci. 1997;94(13):6971–6.
Article
CAS
Google Scholar
Malthus TR, Winch D, James P. Malthus: an essay on the principle of population. Cambridge University Press. 1992.
Klinkenberg, D., Fraser, C., Heesterbeek, H.: The effectiveness of contact tracing in emerging epidemics. PloS one 1(1) (2006).
Gompertz, B.: Xxiv. On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies. in a letter to francis baily, esq. frs &c. Philosophical transactions of the Royal Society of London (115), 513–583 (1825).
Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-ncov) infections among travellers from Wuhan, China, 20–28 january 2020. Eurosurveillance. 2020;25(5).
Arons MM, Hatfield KM, Reddy SC, Kimball A, James A, Jacobs JR, Taylor J, Spicer K, Bardossy AC, Oakley LP, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med. 2020. doi: https://doi.org/10.1056/NEJMoa2008457.
Grein J, Ohmagari N, Shin D, Diaz G, Asperges E, Castagna A, Feldt T, Green G, Green ML, Lescure F-X, Nicastri E, Oda R, Yo K, Quiros-Roldan E, Studemeister A, Redinski J, Ahmed S, Bernett J, Chelliah D, Chen D, Chihara S, Cohen SH, Cunningham J, D’Arminio Monforte A, Ismail S, Kato H, Lapadula G, L’Her E, Maeno T, Majumder S, Massari M, Mora-Rillo M, Mutoh Y, Nguyen D, Verweij E, Zoufaly A, Osinusi AO, DeZure A, Zhao Y, Zhong L, Chokkalingam A, Elboudwarej E, Telep L, Timbs L, Henne I, Sellers S, Cao H, Tan SK, Winterbourne L, Desai P, Mera R, Gaggar A, Myers RP, Brainard DM, Childs R, Flanigan T. Compassionate use of remdesivir for patients with severe covid-19. New England J Med. 2020. https://doi.org/10.1056/NEJMoa2007016.
Wang, Y., Zhang, D., Du, G., Du, R., Zhao, J., Jin, Y., Fu, S., Gao, L., Cheng, Z., Lu, Q., Hu, Y., Luo, G., Wang, K., Lu, Y., Li, H., Wang, S., Ruan, S., Yang, C., Mei, C., Wang, Y., Ding, D., Wu, F., Tang, X., Ye, X., Ye, Y., Liu, B., Yang, J., Yin, W., Wang, A., Fan, G., Zhou, F., Liu, Z., Gu, X., Xu, J., Shang, L., Zhang, Y., Cao, L., Guo, T., Wan, Y., Qin, H., Jiang, Y., Jaki, T., Hayden, F.G., Horby, P.W., Cao, B., Wang, C.: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. The Lancet 2020; 395(10236):1569-1578.
Norrie JD. Remdesivir for COVID-19: challenges of underpowered studies. Lancet. 2020. https://doi.org/10.1016/S0140-6736(20)31023-0.
Merad M, Martin JC. Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages. Nat Rev Immunol. 2020. https://doi.org/10.1038/s41577-020-0331-4.
Richardson S, Hirsch JS, Narasimhan M, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA Published online April 22, 2020. doi:https://doi.org/10.1001/jama.2020.6775.
Remdesivir shows modest benefit in coronavirus trial. (2020). New York Times https://www.nytimes.com/2020/04/29/health/gilead-remdesivir-coronavirus.html. Accessed 13 May 2020.
Mossong J, Hens N, Jit M, Beutels P, Auranen K, Mikolajczyk R, Massari M, Salmaso S, Tomba GS, Wallinga J, Heijne J, SadkowskaTodys M, Rosinska M, Edmunds WJ. Social contacts and mixing patterns relevant to the spread of infectious diseases. PLoS Med. 2008;5(3):1–1. https://doi.org/10.1371/journal.pmed.0050074.
Article
Google Scholar