Fig. 1
From: P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss
Placental P-glycoprotein (P-gp) expression and fetal cord serum cortisol concentrations in control and intrauterine growth retardation (IUGR) neonates. A, B Immunostaining of P-gp in the human female and male placenta (400×). C, D Relative mRNA and protein expression levels of P-gp in the female and male placentas; E, F Cortisol levels in the female (n=9 for control, n=13 for IUGR) and male (n=21 for control, n=13 for IUGR) placentas and fetal cord serum; G Correlations between placental P-gp protein levels and fetal cortisol concentrations; H Correlations between neonatal birth weights and placental P-gp protein levels; I Correlations between neonatal birth weights and fetal cord serum cortisol concentrations in females (n=22) and males (n=34). Mean ± S.E.M. *P<0.05, **P<0.01 vs. control