Brotons P, Launes C, Buetas E, Fumado V, Henares D, de Sevilla MF, et al. Susceptibility to SARS-CoV-2 infection among children and adults: a seroprevalence study of family households in the Barcelona Metropolitan Region, Spain. Clin Infect Dis. 2020;72(12):ciaa1721.
Google Scholar
Cruz AT, Zeichner SL. COVID-19 in children: initial characterization of the pediatric disease. Pediatrics. 2020;145(6):e20200834. https://doi.org/10.1542/peds.2020-0834.
Article
PubMed
Google Scholar
Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 infection in children. New Eng J Med. 2020;382(17):1663–5. https://doi.org/10.1056/NEJMc2005073.
Article
PubMed
Google Scholar
Ludvigsson JF. Children are unlikely to be the main drivers of the COVID-19 pandemic - a systematic review. Acta Paediatr. 2020;109(8):1525–30. https://doi.org/10.1111/apa.15371.
Article
CAS
PubMed
Google Scholar
Bi Q, Wu Y, Mei S, Ye C, Zou X, Zhang Z, et al. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study. Lancet Infect Dis. 2020;20(8):911–9. https://doi.org/10.1016/S1473-3099(20)30287-5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cao Q, Chen Y-C, Chen C-L, Chiu C-H. SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics. J Formos Med Assoc. 2020;119(3):670–3. https://doi.org/10.1016/j.jfma.2020.02.009.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kelvin AA, Halperin S. COVID-19 in children: the link in the transmission chain. Lancet Infect Dis. 2020;20(6):633–4. https://doi.org/10.1016/S1473-3099(20)30236-X.
Article
CAS
PubMed
PubMed Central
Google Scholar
Liguoro I, Pilotto C, Bonanni M, Ferrari ME, Pusiol A, Nocerino A, et al. SARS-COV-2 infection in children and newborns: a systematic review. Eur J Pediatr. 2020;179(7):1029–46. https://doi.org/10.1007/s00431-020-03684-7.
Article
CAS
PubMed
Google Scholar
Mallapaty S. How do children spread the coronavirus? The science still isn’t clear. Nature. 2020;581(7807):127–8. https://doi.org/10.1038/d41586-020-01354-0.
Article
CAS
PubMed
Google Scholar
Davies NG, Klepac P, Liu Y, Prem K, Jit M, Pearson CAB, et al. Age-dependent effects in the transmission and control of COVID-19 epidemics. Nat Med. 2020;26(8):1205–11. https://doi.org/10.1038/s41591-020-0962-9.
Article
CAS
PubMed
Google Scholar
Khan T, Rahman M, Al AF, SSY H, Ata M, Zhang Q, et al. Distinct antibody repertoires against endemic human coronaviruses in children and adults. JCI Insight. 2021;6(4):e144499.
PubMed Central
Google Scholar
Nogrady B. How kids’ immune systems can evade COVID. Nature. 2020;588:382.
Pavel AB, Wu J, Renert-Yuval Y, Del Duca E, Glickman JW, Miller RL, et al. SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age. Allergy. 2020;76(3):875–878. https://doi.org/10.1111/all.14522.
Esteve-Sole A, Anton J, Pino-Ramírez RM, Sanchez-Manubens J, Fumadó V, Fortuny C, et al. Similarities and differences between the immunopathogenesis of COVID-19-related pediatric inflammatory multisystem syndrome and Kawasaki disease. J Clin Invest. 2021;131(6):144554. https://doi.org/10.1172/JCI144554.
Article
PubMed
Google Scholar
Yüce M, Filiztekin E, Özkaya KG. COVID-19 diagnosis -a review of current methods. Biosens Bioelectron. 2021;172:112752. https://doi.org/10.1016/j.bios.2020.112752.
Article
CAS
PubMed
Google Scholar
Péré H, Podglajen I, Wack M, Flamarion E, Mirault T, Goudot G, et al. Nasal swab sampling for SARS-CoV-2: a convenient alternative in times of nasopharyngeal swab shortage. McAdam AJ, editor. J Clin Microbiol. 2020;58(6):e00721–0. https://doi.org/10.1128/JCM.00721-20.
Article
PubMed
PubMed Central
Google Scholar
Teo AKJ, Choudhury Y, Tan IB, Cher CY, Chew SH, Wan ZY, et al. Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection. Sci Rep. 2021;11(1):3134. https://doi.org/10.1038/s41598-021-82787-z.
Article
CAS
PubMed
PubMed Central
Google Scholar
Griffin SM, Converse RR, Leon JS, Wade TJ, Jiang X, Moe CL, et al. Application of salivary antibody immunoassays for the detection of incident infections with Norwalk virus in a group of volunteers. J Immunol Methods. 2015 Sep;424:53–63. https://doi.org/10.1016/j.jim.2015.05.001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wade TJ, Griffin SM, Egorov AI, Sams E, Hudgens E, Augustine S, et al. Application of a multiplex salivary immunoassay to detect sporadic incident norovirus infections. Sci Rep. 2019;9(1):19576. https://doi.org/10.1038/s41598-019-56040-7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pisanic N, Randad PR, Kruczynski K, Manabe YC, Thomas D, Pekosz A, et al. COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva. J Clin Microbilology. 2021;59(1):e02204–20. https://doi.org/10.1128/JCM.02204-20.
Dobaño C, Vidal M, Santano R, Jiménez A, Chi J, Barrios D, et al. Highly sensitive and specific multiplex antibody assays to quantify immunoglobulins M, A and G against SARS-CoV-2 antigens. J Clin Microbiol. 2020;59(2):e01731–20. https://doi.org/10.1128/JCM.01731-20.
Article
Google Scholar
Sterlin D, Mathian A, Miyara M, Mohr A, Anna F, Claër L, et al. IgA dominates the early neutralizing antibody response to SARS-CoV-2. Sci Transl Med. 2021;13(577):eabd2223.
Article
CAS
Google Scholar
Nishanian P, Aziz N, Chung J, Detels R, Fahey JL. Oral fluids as an alternative to serum for measurement of markers of immune activation. Clin Diagn Lab Immunol. 1998 Jul;5(4):507–12. https://doi.org/10.1128/CDLI.5.4.507-512.1998.
Article
CAS
PubMed
PubMed Central
Google Scholar
McKie A, Vyse A, Maple C. Novel methods for the detection of microbial antibodies in oral fluid. Lancet Infect Dis. 2002;2(1):18–24. https://doi.org/10.1016/S1473-3099(01)00169-4.
Article
CAS
PubMed
Google Scholar
Jordan I, de Sevilla MF, Fumado V, Bassat Q, Bonet-Carne E, Fortuny C, et al. Transmission of SARS-CoV-2 infection among children in summer schools applying stringent control measures in Barcelona, Spain. Clin Infect Dis. 2021;ciab227. https://doi.org/10.1093/cid/ciab227. Online ahead of print.
Dobaño C, Santano R, Jiménez A, Vidal M, Chi J, Rodrigo Melero N, et al. Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies. Transl Res. 2021;S1931-5244(21):00029–3.
Google Scholar
Marks M, Millat-Martinez P, Ouchi D, Roberts CH, Alemany A, Corbacho-Monné M, et al. Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study. Lancet Infect Dis. 2021;21(5):629–36. https://doi.org/10.1016/S1473-3099(20)30985-3.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bellon M, Baggio S, Bausch FJ, Spechbach H, Salamun J, Genecand C, et al. SARS-CoV-2 viral load kinetics in symptomatic children, adolescents and adults. Clin Infect Dis. 2021;73(6):e1384–6 ciab396.
Article
CAS
Google Scholar
Kociolek LK, Muller WJ, Yee R, Dien Bard J, Brown CA, Revell PA, et al. Comparison of upper respiratory viral load distributions in asymptomatic and symptomatic children diagnosed with SARS-CoV-2 infection in pediatric hospital testing programs. J Clin Microbiol. 2020;59(1):e02593–20. https://doi.org/10.1128/JCM.02593-20.
Article
PubMed
PubMed Central
Google Scholar
Iwasaki S, Fujisawa S, Nakakubo S, Kamada K, Yamashita Y, Fukumoto T, et al. Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva. J Infect. 2020;81(2):e145–7. https://doi.org/10.1016/j.jinf.2020.05.071.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tosif S, Neeland MR, Sutton P, Licciardi PV, Sarkar S, Selva KJ, et al. Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19. Nat Commun. 2020;11(1):5703. https://doi.org/10.1038/s41467-020-19545-8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yang HS, Costa V, Racine-Brzostek SE, Acker KP, Yee J, Chen Z, et al. Association of Age With SARS-CoV-2 Antibody Response. JAMA. 2021;4(3):e214302. https://doi.org/10.1001/jamanetworkopen.2021.4302.
Article
Google Scholar
Russell MW, Moldoveanu Z, Ogra PL, Mestecky J. Mucosal immunity in COVID-19: a neglected but critical aspect of SARS-CoV-2 infection. Front Immunol. 2020;11:3221. https://doi.org/10.3389/fimmu.2020.611337.
Article
CAS
Google Scholar
Sheikh-Mohamed S, Isho B, Chao GYC, Zuo M, Nahass GR, Salomon-Shulman RE, et al. A mucosal antibody response is induced by intra-muscular SARS-CoV-2 mRNA vaccination. MedRxiv. https://doi.org/10.1101/2021.08.01.21261297.
Cervia C, Nilsson J, Zurbuchen Y, Valaperti A, Schreiner J, Wolfensberger A, et al. Systemic and mucosal antibody secretion specific to SARS-CoV-2 during mild versus severe COVID-19. J Allergy Clin Immunol. 2021;147(2):545–557.e9.
Article
CAS
Google Scholar
Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, et al. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol. 2020;5(52):eabe5511.
Article
Google Scholar
Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, et al. Immunological memory to SARS-CoV-2 assessed for up to eight months after infection. Science (80- ). 2021;371(6529):eabf4063.
Article
CAS
Google Scholar
Dobaño C, Ramirez A, Alonso S, Vidal-Alaball J, Ruiz-Olalla G, Vidal M, et al. Persistence and baseline determinants of seropositivity in health care workers up to nine months after COVID-19. BMC Med. 2021;19(1):155. https://doi.org/10.1186/s12916-021-02032-2.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ortega N, Ribes M, Vidal M, Rubio R, Aguilar R, Williams S, et al. Seven-month kinetics of SARS-CoV-2 antibodies and protective role of pre-existing antibodies to seasonal human coronaviruses on COVID-19. Nat Commun. 2021;12(1):4740. https://doi.org/10.1038/s41467-021-24979-9.
Article
CAS
PubMed
PubMed Central
Google Scholar