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Table 1 Baseline characteristics of study participants in the prospective study of dementia

From: Plasma metabolomic profiles of dementia: a prospective study of 110,655 participants in the UK Biobank

Baseline Characteristics Overall
(N= 110,655)
Individuals with incident dementia
(n=1439)
Individuals without incident dementia
(n=109,216)
P value
Age, mean (SD), years 56.5 (8.10) 64.2 (4.88) 56.4 (8.08) <0.001
Gender, No. (%)     <0.001
 Female 59,469 (53.7) 652 (45.3) 58,817 (53.9)  
 Male 51,186 (46.3) 787 (54.7) 50,399 (46.1)  
Education level, No. (%)     <0.001
 College or university degree 35,744 (32.3) 301 (20.9) 35,443 (32.5)  
 Others 74,911 (67.7) 1138 (79.1) 73,773 (67.5)  
Systolic pressure, mean (SD), mmHg 137 (18.5) 143 (19.3) 138 (18.5) <0.001
Anti-hypertension treatment, No. (%)     <0.001
 No 100,148 (90.5) 1211 (84.2) 98,937 (90.6)  
 Yes 10,507 (9.50) 228 (15.8) 10,279 (9.41)  
Diabetes mellitus, No. (%)     <0.001
 No 103,950 (93.9) 1207 (83.9) 102,743 (94.1)  
 Yes 6705 (6.06) 232 (16.1) 6473 (5.93)  
Smoking status, No. (%)     <0.001
 Never 60,195 (54.7) 666 (46.6) 59,529 (54.8)  
 Former/current 49,896 (45.3) 762 (53.4) 49,134 (45.2)  
History of stroke, No. (%)     <0.001
 No 109,108 (98.6) 1361 (94.6) 107,747 (98.7)  
 Yes 1547 (1.40) 78 (5.42) 1469 (1.35)  
History of coronary heart disease, No. (%)     <0.001
 No 106,067 (95.9) 1267 (88.1) 104,800 (96.0)  
 Yes 4588 (4.15) 172 (12.0) 4416 (4.04)  
APOE ε4 carrier, No. (%)     <0.001
 No 83,454 (75.8) 795 (55.6) 82,649 (76.0)  
 Yes 26,675 (24.2) 635 (44.4) 26,040 (24.0)  
  1. SD standard deviation, No. number