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Table 1 Baseline characteristics of study participants in the prospective study of dementia

From: Plasma metabolomic profiles of dementia: a prospective study of 110,655 participants in the UK Biobank

Baseline Characteristics

Overall

(N= 110,655)

Individuals with incident dementia

(n=1439)

Individuals without incident dementia

(n=109,216)

P value

Age, mean (SD), years

56.5 (8.10)

64.2 (4.88)

56.4 (8.08)

<0.001

Gender, No. (%)

   

<0.001

 Female

59,469 (53.7)

652 (45.3)

58,817 (53.9)

 

 Male

51,186 (46.3)

787 (54.7)

50,399 (46.1)

 

Education level, No. (%)

   

<0.001

 College or university degree

35,744 (32.3)

301 (20.9)

35,443 (32.5)

 

 Others

74,911 (67.7)

1138 (79.1)

73,773 (67.5)

 

Systolic pressure, mean (SD), mmHg

137 (18.5)

143 (19.3)

138 (18.5)

<0.001

Anti-hypertension treatment, No. (%)

   

<0.001

 No

100,148 (90.5)

1211 (84.2)

98,937 (90.6)

 

 Yes

10,507 (9.50)

228 (15.8)

10,279 (9.41)

 

Diabetes mellitus, No. (%)

   

<0.001

 No

103,950 (93.9)

1207 (83.9)

102,743 (94.1)

 

 Yes

6705 (6.06)

232 (16.1)

6473 (5.93)

 

Smoking status, No. (%)

   

<0.001

 Never

60,195 (54.7)

666 (46.6)

59,529 (54.8)

 

 Former/current

49,896 (45.3)

762 (53.4)

49,134 (45.2)

 

History of stroke, No. (%)

   

<0.001

 No

109,108 (98.6)

1361 (94.6)

107,747 (98.7)

 

 Yes

1547 (1.40)

78 (5.42)

1469 (1.35)

 

History of coronary heart disease, No. (%)

   

<0.001

 No

106,067 (95.9)

1267 (88.1)

104,800 (96.0)

 

 Yes

4588 (4.15)

172 (12.0)

4416 (4.04)

 

APOE ε4 carrier, No. (%)

   

<0.001

 No

83,454 (75.8)

795 (55.6)

82,649 (76.0)

 

 Yes

26,675 (24.2)

635 (44.4)

26,040 (24.0)

 
  1. SD standard deviation, No. number