From: Heterogeneity in pragmatic randomised trials: sources and management
Patients: Adults surviving spontaneous intracerebral haemorrhage Centres: 122 hospitals in the UK Intervention: Antiplatelet therapy Control: Usual care Outcome: Recurrence of symptomatic intracerebral haemorrhage (see below) Design: Two parallel-group individually randomised trial | |
Outcome | “Although we did not mask the assigned treatment to participants and physicians, the outcomes were objective and adjudicated masked to treatment allocation, which minimises bias.” |