Table 4 Ingenuity pathway analysis canonical pathways of genes annotated to the top 100 social support associated methylation sites in placenta (total sample, n = 301)
From: Prenatal social support in low-risk pregnancy shapes placental epigenome
Ingenuity canonical pathways | Log P-value | Ratio | Molecules |
|---|---|---|---|
Extrinsic prothrombin activation pathway | 2.71 | 0.125 | F3, THBD |
Coagulation system | 2.04 | 0.057 | F3, THBD |
White adipose tissue browning pathway | 1.72 | 0.022 | ADCY9, FGFR1, VGF |
Regulation of eIF4 and p70S6K signaling | 1.42 | 0.017 | AGO3, EIF3F, ITGAE |
Synaptogenesis signaling pathway | 1.38 | 0.013 | ADCY9, ARHGEF7, EFNA5, THBS2 |
FGF signaling | 1.33 | 0.024 | FGFR1, FRS2 |
Hippo signaling | 1.32 | 0.024 | SCRIB, TEAD4 |