Table 3 Combined association of SCP and ICP with dementia among Chinese (N = 8112) and European (N = 44,849) middle-aged and older participants

China Health and Retirement Longitudinal Study (CHARLS): Probable dementia, OR (95% CI)^a

 N

4495

2276

632

709

 Cases

425

405

100

190

 Age-adjusted model

1 (ref.)

2.03 (1.75, 2.36) *

1.47 (1.15, 1.87) *

2.89 (2.37, 3.53) *

 Multivariate model 1 (MV1)

1 (ref.)

1.47 (1.25, 1.72) *

1.18 (0.91, 1.52)

1.77 (1.42, 2.20) *

Survey of Health, Ageing and Retirement in Europe (SHARE): Diagnosed dementia, HR (95% CI)^b

 N

31,259

11,152

1276

1162

 Cases

637

672

64

151

 Person-years

190,818

66,394

7424

6142

 Incidence rate^d

333.8

1012.1

862.1

2458.5

 Age-adjusted model

1 (ref.)

2.27 (2.03, 2.53) *

1.98 (1.53, 2.56) *

4.27 (3.56, 5.13) *

 Multivariate model 1 (MV1)

1 (ref.)

1.99 (1.77, 2.24) *

1.61 (1.24, 2.10) *

2.94 (2.42, 3.59) *

Pooled results^c

 Multivariate model 1 (MV1)

1 (ref.)

1.72 (1.28, 2.31) *

1.38 (1.01, 1.88) *

2.29 (1.38, 3.77) *