Huggins C, Hodges CV: Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941. J Urol. 2002, 168: 9-12. 10.1016/S0022-5347(05)64820-3.
Article
PubMed
Google Scholar
Mottet N, Bellmunt J, Bolla M, Joniau S, Mason M, Matveev V, Schmid HP, Van der Kwast T, Wiegel T, Zattoni F, Heidenreich A: EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol. 2011, 59: 572-583. 10.1016/j.eururo.2011.01.025.
Article
PubMed
Google Scholar
Iversen P, Melezinek I, Schmidt A: Nonsteroidal antiandrogens: a therapeutic option for patients with advanced prostate cancer who wish to retain sexual interest and function. BJU Int. 2001, 87: 47-56. 10.1046/j.1464-410x.2001.00988.x.
Article
CAS
PubMed
Google Scholar
Carswell CI, Figgitt DP: Bicalutamide: in early-stage prostate cancer. Drugs. 2002, 62: 2471-2479. 10.2165/00003495-200262170-00006. discussion 2480-2471
Article
CAS
PubMed
Google Scholar
McLeod DG, Iversen P: Gynecomastia in patients with prostate cancer: a review of treatment options. Urology. 2000, 56: 713-720. 10.1016/S0090-4295(00)00823-2.
Article
CAS
PubMed
Google Scholar
Wirth MP, See WA, McLeod DG, Iversen P, Morris T, Carroll K: Bicalutamide 150 mg in addition to standard care in patients with localized or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median followup of 5.4 years. J Urol. 2004, 172: 1865-1870. 10.1097/01.ju.0000140159.94703.80.
Article
CAS
PubMed
Google Scholar
McLeod DG, Iversen P, See WA, Morris T, Armstrong J, Wirth MP: Bicalutamide 150 mg plus standard care vs standard care alone for early prostate cancer. BJU Int. 2006, 97: 247-254. 10.1111/j.1464-410X.2005.06051.x.
Article
CAS
PubMed
Google Scholar
Boccardo F, Rubagotti A, Battaglia M, Di Tonno P, Selvaggi FP, Conti G, Comeri G, Bertaccini A, Martorana G, Galassi P, Zattoni F, Macchiarella A, Siragusa A, Muscas G, Durand F, Potenzoni D, Manganelli A, Ferraris V, Montefiore F: Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer. J Clin Oncol. 2005, 23: 808-815. 10.1200/JCO.2005.12.013.
Article
CAS
PubMed
Google Scholar
Perdona S, Autorino R, De Placido S, D'Armiento M, Gallo A, Damiano R, Pingitore D, Gallo L, De Sio M, Bianco AR, Di Lorenzo G: Efficacy of tamoxifen and radiotherapy for prevention and treatment of gynaecomastia and breast pain caused by bicalutamide in prostate cancer: a randomised controlled trial. Lancet Oncol. 2005, 6: 295-300. 10.1016/S1470-2045(05)70103-0.
Article
CAS
PubMed
Google Scholar
Staiman VR, Lowe FC: Tamoxifen for flutamide/finasteride-induced gynecomastia. Urology. 1997, 50: 929-933. 10.1016/S0090-4295(97)00457-3.
Article
CAS
PubMed
Google Scholar
Parker LN, Gray DR, Lai MK, Levin ER: Treatment of gynecomastia with tamoxifen: A double-blind crossover study. Metabolism. 1986, 35: 705-708. 10.1016/0026-0495(86)90237-4.
Article
CAS
PubMed
Google Scholar
Fradet Y, Egerdie B, Andersen M, Tammela TLJ, Nachabe M, Armstrong J, Morris T, Navani S: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study. Eur Urol. 2007, 52: 106-114. 10.1016/j.eururo.2007.01.031.
Article
CAS
PubMed
Google Scholar
Saltzstein D, Sieber P, Morris T, Gallo J: Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole. Prostate Cancer Prostatic Dis. 2005, 8: 75-83. 10.1038/sj.pcan.4500782.
Article
CAS
PubMed
Google Scholar
Di Lorenzo G, Autorino R: Bicalutamide-induced gynaecomastia: do we have the answer?. Eur Urol. 2007, 52: 5-8. 10.1016/j.eururo.2007.01.063.
Article
PubMed
Google Scholar
Di Lorenzo G, Autorino R, Perdona S, De Placido S: Management of gynaecomastia in patients with prostate cancer: a systematic review. Lancet Oncol. 2005, 6: 972-979. 10.1016/S1470-2045(05)70464-2.
Article
PubMed
Google Scholar
Autorino R, Perdona S, D'Armiento M, De Sio M, Damiano R, Cosentino L, Di Lorenzo G: Gynecomastia in patients with prostate cancer: update on treatment options. Prostate Cancer Prostatic Dis. 2006, 9: 109-114. 10.1038/sj.pcan.4500859.
Article
CAS
PubMed
Google Scholar
Boccardo F, Rubagotti A, Garofalo L, Di Tonno P, Conti G, Bertaccini A, De Antoni P, Galassi P, Siragusa A, Durand F: Tamoxifen (T) is more effective than anastrozole (A) in preventing gynecomastia induced by bicalutamide (B) monotherapy in prostate cancer (pca) patients (pts). 39th Annual Meeting of the American Society of Clinical Oncology, Chicago. 2003, May 31-June 3, Abstract 1608
Google Scholar
Boccardo F, Rubagotti A, Conti G, Potenzoni D, Manganelli A, Del Monaco D: Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer. Cancer Chemother Pharmacol. 2005, 56: 415-420. 10.1007/s00280-005-1016-1.
Article
CAS
PubMed
Google Scholar
Conti G, Cretarola E, Boccardo F, Battaglia M, Di Tonno P, Bertaccini A, De Antoni P, Zattoni F, Galassi P, Durand F: Tamoxifen is safe and effective in preventing gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer and does not alter treatment efficacy. 19th Congress of the European Association of Urology, Vienna. 2004
Google Scholar
Fradet Y, Egerdie B, Andersen M, Tammela T, Nachabe M, Armstrong J, Morris T, Navani S: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer. 22nd Annual Congress of the European Association of Urology, Berlin. 2007
Google Scholar
Di Lorenzo G, Perdona S, De Placido S, D'Armiento M, Gallo A, Damiano R, Pingitore D, Gallo L, De Sio M, Autorino R: Gynecomastia and breast pain induced by adjuvant therapy with bicalutamide after radical prostatectomy in patients with prostate cancer: the role of tamoxifen and radiotherapy. J Urol. 2005, 174: 2197-2203. 10.1097/01.ju.0000181824.28382.5c.
Article
CAS
PubMed
Google Scholar
Saltzstein D, Cantwell A, Sieber P, Ross JR, Silvay-Mandeau O, Gallo J: Prophylactic tamoxifen significantly reduces the incidence of bicalutamide-induced gynaecomastia and breast pain. BJU Int. 2002, 90 (Suppl 2): 119-122.
Google Scholar
Bedognetti D, Rubagotti A, Conti G, Francesca F, De Cobelli O, Canclini L, Galucci F, Aragona F, Di Tonno P, Boccardo F: An open, randomized, multicentre, phase III trial comparing the efficacy of two tamoxifen (T) schedules in preventing gynecomastia (gy) induced by bicalutamide monotherapy (BM) in prostate cancer patients (pca pts). J Clin Oncol. 2009, 27: e16080.
Google Scholar
Bedognetti D, Rubagotti A, Conti G, Francesca F, De Cobelli O, Canclini L, Gallucci M, Aragona F, Di Tonno P, Cortellini P, Martorana G, Lapini A, Boccardo F: An open, randomised, multicentre, phase 3 trial comparing the efficacy of two tamoxifen schedules in preventing gynaecomastia induced by bicalutamide monotherapy in prostate cancer patients. Eur Urol. 2010, 57: 238-245. 10.1016/j.eururo.2009.05.019.
Article
PubMed
Google Scholar
Eaton AC, Makris A: Once weekly tamoxifen in the prevention of gynaecomastia and breast pain secondary to bicalutamide therapy. Congress of the American Urological Association, San Francisco. 2004, a1069.
Google Scholar
Ozen H, Akyol F, Toktas G, Eskicorapci S, Unluer E, Kuyumcuoglu U, Abay E, Cureklibatur I, Sengoz M, Yalcin V, Akpinar H, Zorlu F, Sengor F, Karaman I: Is prophylactic breast radiotherapy necessary in all patients with prostate cancer and gynecomastia and/or breast pain?. J Urol. 2010, 184: 519-524. 10.1016/j.juro.2010.03.137.
Article
PubMed
Google Scholar
Van Poppel H: Editorial comment on: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study. Eur Urol. 2007, 52: 115-10.1016/j.eururo.2007.01.032.
Article
PubMed
Google Scholar
Ryssel H, Germann G, Kollensperger E, Riedel K: Plastic surgery for the treatment of gynaecomastia following hormone therapy in prostate carcinoma. Urologe A. 2008, 47: 467-471. 10.1007/s00120-007-1567-3.
Article
CAS
PubMed
Google Scholar
Tyrrell CJ, Payne H, Tammela TL, Bakke A, Lodding P, Goedhals L, Van Erps P, Boon T, Van De Beek C, Andersson SO, Morris T, Carroll K: Prophylactic breast irradiation with a single dose of electron beam radiotherapy (10 Gy) significantly reduces the incidence of bicalutamide-induced gynecomastia. Int J Radiat Oncol Biol Phys. 2004, 60: 476-483. 10.1016/j.ijrobp.2004.03.022.
Article
PubMed
Google Scholar
Widmark A, Fossa SD, Lundmo P, Damber JE, Vaage S, Damber L, Wiklund F, Klepp O: Does prophylactic breast irradiation prevent antiandrogen-induced gynecomastia? Evaluation of 253 patients in the randomized Scandinavian trial SPCG-7/SFUO-3. Urology. 2003, 61: 145-151. 10.1016/S0090-4295(02)02107-6.
Article
CAS
PubMed
Google Scholar
Mermershtain W, Lazarev I, Regev E, Ariad S, Lavrenkov K: Prophylactic breast irradiation for prevention of gynecomastia caused by antiandrogen therapy with bicalutamide (casodex 150 mg/d) for prostatic cancer patients. 1st European Multidisciplinary Meeting on Urological Cancer, Barcelona. 2007
Google Scholar
Fass D, Steinfeld A, Brown J, Tessler A: Radiotherapeutic prophylaxis of estrogen-induced gynecomastia: a study of late sequela. Int J Radiation Oncology Biol Phys. 1986, 12: 407-408. 10.1016/0360-3016(86)90359-7.
Article
CAS
Google Scholar
Van Poppel H, Tyrrell CJ, Haustermans K, Cangh PV, Keuppens F, Colombeau P, Morris T, Garside L: Efficacy and tolerability of radiotherapy as treatment for bicalutamide-induced gynaecomastia and breast pain in prostate cancer. Eur Urol. 2005, 47: 587-592. 10.1016/j.eururo.2004.12.003.
Article
CAS
PubMed
Google Scholar
Dicker AP: The safety and tolerability of low-dose irradiation for the management of gynaecomastia caused by antiandrogen monotherapy. Lancet Oncol. 2003, 4: 30-36. 10.1016/S1470-2045(03)00958-6.
Article
PubMed
Google Scholar
Nieder C, Pawinski A, Andratschke NH, Molls M: Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?. Radiat Oncol. 2008, 3: 2-10.1186/1748-717X-3-2.
Article
PubMed
PubMed Central
Google Scholar
Rohrich RJ, Ha RY, Kenkel JM, Adams WP: Classification and management of gynecomastia: defining the role of ultrasound-assisted liposuction. Plast Reconstr Surg. 2003, 111: 909-923. 10.1097/01.PRS.0000042146.40379.25. discussion 924-905
Article
PubMed
Google Scholar
Boccardo F, Rubagotti A, Battaglia M, Zattoni F, Bertaccini A, Romagnoli A, Conti G: Influence of bicalutamide with or without tamoxifen or anastrozole on insulin-like growth factor 1 and binding proteins in prostate cancer patients. Int J Biol Markers. 2006, 21: 123-126.
CAS
PubMed
Google Scholar
Serretta V, Allegro R, De Grande G, Nicolosi F, Iurato C, Mazza R, Oxenius I, Cosentino V, Vaccarella G, Falsaperla M, Melloni D, Karydi M: Management of bicalutamide induced gynaecomastia. A randomised study comparing therapy versus prophylaxis with tamoxifen. 23rd Annual Congress of the European Association of Urology, Milan. 2008
Google Scholar
Serretta V, De Grande G, Lapira G, Nicolosi F, Iurato C, De Giacomo E, Ranno S, Cosentino V, Contino G, Falsaperla M, Melloni D, Antonia R, Allegro R: A randomized trial comparing tamoxifen therapy versus tamoxifen prophylaxis in bicalutamide induced gynecomastia. J Urol. 2008, 179 (4 Supplement): 181.
Article
Google Scholar