Cordon-Cardo C, Prives C: At the crossroads of inflammation and tumorigenesis. J Exp Med. 1999, 190: 1367-1370. 10.1084/jem.190.10.1367.
Article
CAS
PubMed
PubMed Central
Google Scholar
Nolan JP, Leibowitz AI: Endotoxins in liver disease. Gastroenterology. 1978, 75: 765-766.
CAS
PubMed
Google Scholar
Triger DR, Boyer TD, Levin J: Portal and systemic bacteraemia and endotoxaemia in liver disease. Gut. 1978, 19: 935-939. 10.1136/gut.19.10.935.
Article
CAS
PubMed
PubMed Central
Google Scholar
Schwabe RF, Seki E, Brenner DA: Toll-like receptor signaling in the liver. Gastroenterology. 2006, 130: 1886-1900. 10.1053/j.gastro.2006.01.038.
Article
CAS
PubMed
Google Scholar
Iwasaki A, Medzhitov R: Toll-like receptor control of the adaptive immune responses. Nat Immunol. 2004, 5: 987-995. 10.1038/ni1112.
Article
CAS
PubMed
Google Scholar
Pidgeon GP, Harmey JH, Kay E, Da Costa M, Redmond HP, Bouchier-Hayes DJ: The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease. Br J Cancer. 1999, 81: 1311-1317. 10.1038/sj.bjc.6694369.
Article
CAS
PubMed
PubMed Central
Google Scholar
Harmey JH, Bucana CD, Lu W, Byrne AM, McDonnell S, Lynch C, Bouchier-Hayes D, Dong Z: Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int J Cancer. 2002, 101 (5): 415-422. 10.1002/ijc.10632.
Article
CAS
PubMed
Google Scholar
Wang JH, Manning BJ, Wu QD, Blankson S, Bouchier-Hayes D, Redmond HP: Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism. J Immunol. 2003, 170: 795-804.
Article
CAS
PubMed
Google Scholar
Liu X, Liang J, Li G: Lipopolysaccharide promotes adhesion and invasion of hepatoma cell lines HepG2 and HepG2.2.15. Mol Biol Rep. 2010, 37: 2235-2239. 10.1007/s11033-009-9710-4.
Article
CAS
PubMed
Google Scholar
Ikebe M, Kitaura Y, Nakamura M, Tanaka H, Yamasaki A, Nagai S, Wada J, Yanai K, Koga K, Sato N, Kubo M, Tanaka M, Onishi H, Katano M: Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway. J Surg Oncol. 2009, 100: 725-731. 10.1002/jso.21392.
Article
CAS
PubMed
Google Scholar
Akira S, Takeda K: Toll-like receptor signalling. Nat Rev. 2004, 4: 499-511.
Article
CAS
Google Scholar
Hua D, Liu MY, Cheng ZD, Qin XJ, Zhang HM, Chen Y, Qin GJ, Liang G, Li JN, Han XF, Liu DX: Small interfering RNA-directed targeting of Toll-like receptor 4 inhibits human prostate cancer cell invasion, survival, and tumorigenicity. Mol Immunol. 2009, 46: 2876-2884. 10.1016/j.molimm.2009.06.016.
Article
CAS
PubMed
Google Scholar
Yu LX, Yan HX, Liu Q, Yang W, Wu HP, Dong W, Tang L, Lin Y, He YQ, Zou SS, Wang C, Zhang HL, Cao GW, Wu MC, Wang HY: Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. Hepatology. 2010, 52: 1322-1333. 10.1002/hep.23845.
Article
CAS
PubMed
Google Scholar
Gonzalez-Reyes S, Marin L, Gonzalez L, Gonzalez LO, del Casar JM, Lamelas ML, Gonzalez-Quintana JM, Vizoso FJ: Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis. BMC Cancer. 2010, 10: 665-10.1186/1471-2407-10-665.
Article
CAS
PubMed
PubMed Central
Google Scholar
Xu Z, Ren T, Xiao C, Li H, Wu T: Nickel promotes the invasive potential of human lung cancer cells via TLR4/MyD88 signaling. Toxicology. 2011, 285: 25-30. 10.1016/j.tox.2011.03.016.
Article
CAS
PubMed
Google Scholar
Wang EL, Qian ZR, Nakasono M, Tanahashi T, Yoshimoto K, Bando Y, Kudo E, Shimada M, Sano T: High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer. Br J Cancer. 2010, 102: 908-915. 10.1038/sj.bjc.6605558.
Article
CAS
PubMed
PubMed Central
Google Scholar
Larue L, Bellacosa A: Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene. 2005, 24: 7443-7454. 10.1038/sj.onc.1209091.
Article
CAS
PubMed
Google Scholar
Zhao L, Yang R, Cheng L, Wang M, Jiang Y, Wang S: LPS-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells. J Surg Res. 2011, 171: 819-25. 10.1016/j.jss.2010.04.059.
Article
CAS
PubMed
Google Scholar
Wu F, Yang LY, Li YF, Ou DP, Chen DP, Fan C: Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma. Hepatology. 2009, 50: 1839-1850. 10.1002/hep.23197.
Article
CAS
PubMed
Google Scholar
Yang MH, Chen CL, Chau GY, Chiou SH, Su CW, Chou TY, Peng WL, Wu JC: Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. Hepatology. 2009, 50: 1464-1474. 10.1002/hep.23221.
Article
CAS
PubMed
Google Scholar
Zhang X, Liu S, Hu T, Liu S, He Y, Sun S: Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. Hepatology. 2009, 50: 490-499. 10.1002/hep.23008.
Article
CAS
PubMed
Google Scholar
Sun T, Zhao N, Zhao XL, Gu Q, Zhang SW, Che N, Wang XH, Du J, Liu YX, Sun BC: Expression and functional significance of Twist1 in hepatocellular carcinoma: its role in vasculogenic mimicry. Hepatology. 2010, 51: 545-556. 10.1002/hep.23311.
Article
CAS
PubMed
Google Scholar
Zhang J, Chen Y, Xin XL, Li QN, Li M, Lin LP, Geng MY, Ding J: Oligomannurarate sulfate blocks tumor growth by inhibiting NF-kappaB activation. Acta Pharmacol Sin. 2010, 31: 375-381. 10.1038/aps.2010.13.
Article
PubMed
PubMed Central
Google Scholar
Szajnik M, Szczepanski MJ, Czystowska M, Elishaev E, Mandapathil M, Nowak-Markwitz E, Spaczynski M, Whiteside TL: TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer. Oncogene. 2009, 28: 4353-4363. 10.1038/onc.2009.289.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huber MA, Azoitei N, Baumann B, Grunert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T: NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest. 2004, 114: 569-581.
Article
CAS
PubMed
PubMed Central
Google Scholar
Condeelis J, Segall JE: Intravital imaging of cell movement in tumours. Nat Rev Cancer. 2003, 3: 921-930. 10.1038/nrc1231.
Article
CAS
PubMed
Google Scholar
Dong R, Wang Q, He XL, Chu YK, Lu JG, Ma QJ: Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-alpha-induced epithelial-mesenchymal transition of MCF-7 cells. Braz J Med Biol Res. 2007, 40: 1071-1078. 10.1590/S0100-879X2007000800007.
Article
CAS
PubMed
Google Scholar
Molteni M, Marabella D, Orlandi C, Rossetti C: Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4. Cancer Lett. 2006, 235: 75-83. 10.1016/j.canlet.2005.04.006.
Article
CAS
PubMed
Google Scholar
van Zijl F, Zulehner G, Petz M, Schneller D, Kornauth C, Hau M, Machat G, Grubinger M, Huber H, W Mikulits: Epithelial to mesenchymal transition in hepatocellular carcinoma. Future Oncol. 2009, 5: 1169-1179. 10.2217/fon.09.91.
Article
CAS
PubMed
Google Scholar
Nakashima H, Nakamura M, Yamaguchi H, Yamanaka N, Akiyoshi T, Koga K, Yamaguchi K, Tsuneyoshi M, Tanaka M, Katano M: Nuclear factor-kappaB contributes to hedgehog signaling pathway activation through sonic hedgehog induction in pancreatic cancer. Cancer Res. 2006, 66: 7041-7049. 10.1158/0008-5472.CAN-05-4588.
Article
CAS
PubMed
Google Scholar
Kojima M, Morisaki T, Izuhara K, Uchiyama A, Matsunari Y, Katano M, Tanaka M: Lipopolysaccharide increases cyclo-oxygenase-2 expression in a colon carcinoma cell line through nuclear factor-kappa B activation. Oncogene. 2000, 19: 1225-1231. 10.1038/sj.onc.1203427.
Article
CAS
PubMed
Google Scholar
Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP: Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell. 2009, 15: 416-428. 10.1016/j.ccr.2009.03.016.
Article
CAS
PubMed
PubMed Central
Google Scholar
Barbera MJ, Puig I, Dominguez D, Julien-Grille S, Guaita-Esteruelas S, Peiro S, Baulida J, Franci C, Dedhar S, Larue L, García de Herreros A: Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells. Oncogene. 2004, 23: 7345-7354. 10.1038/sj.onc.1207990.
Article
CAS
PubMed
Google Scholar
Criswell TL, Arteaga CL: Modulation of NFkappaB activity and E-cadherin by the type III transforming growth factor beta receptor regulates cell growth and motility. J Biol Chem. 2007, 282: 32491-32500. 10.1074/jbc.M704434200.
Article
CAS
PubMed
Google Scholar
Franco DL, Mainez J, Vega S, Sancho P, Murillo MM, de Frutos CA, Del Castillo G, Lopez-Blau C, Fabregat I, Nieto MA: Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes. J Cell Sci. 2010, 123: 3467-3477. 10.1242/jcs.068692.
Article
CAS
PubMed
Google Scholar
Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, Garcia De Herreros A: The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol. 2000, 2: 84-89. 10.1038/35000034.
Article
CAS
PubMed
Google Scholar
Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, Portillo F, Nieto MA: The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol. 2000, 2: 76-83. 10.1038/35000025.
Article
CAS
PubMed
Google Scholar
Cammarota R, Bertolini V, Pennesi G, Bucci EO, Gottardi O, Garlanda C, Laghi L, Barberis MC, Sessa F, Noonan DM, Albini A: The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker. J Transl Med. 2010, 8: 112-10.1186/1479-5876-8-112.
Article
PubMed
PubMed Central
Google Scholar
Velazquez RF, Rodriguez M, Navascues CA, Linares A, Perez R, Sotorrios NG, Martinez I, Rodrigo L: Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis. Hepatology. 2003, 37: 520-527. 10.1053/jhep.2003.50093.
Article
PubMed
Google Scholar
Poon RT, Fan ST, Lo CM, Liu CL, Wong J: Difference in tumor invasiveness in cirrhotic patients with hepatocellular carcinoma fulfilling the Milan criteria treated by resection and transplantation: impact on long-term survival. Ann Surg. 2007, 245: 51-58. 10.1097/01.sla.0000225255.01668.65.
Article
PubMed
PubMed Central
Google Scholar