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Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study
BMC Medicine volume 16, Article number: 159 (2018)
The original article  contains errors in Table 1 affecting some of the presented oligonucleotide sequences and readthrough values in Table 1.
The corrected Table 1 displayed below shows the correct presentation of the affected oligonucleotide sequences for mutations Y122X, W128X, and G542X, as well as the correct readthrough values in columns ‘0’ and ‘600’ for the Y122X mutation. These corrections also extend to the corresponding data mentioned in the first paragraph of the Results section and Supplemental Table 1. Whatever the mutation, gentamicin induced readthrough remained very moderate which explains the absence of changes in patients harboring G542X, R1162X and W1282X mutation. This is in contrast to Y122X patients, who unexpectedly demonstrated restoration of adequate levels of functional protein in vivo inspite of low readthrough levels observed in vitro. One explanation could be a lower efficiency of the nonsense mediated mRNA (NMD) pathway in the cells of these patients, which can not be revealed with the dual reporter system.
Sermet-Gaudelus I, et al. In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med. 2007;5:5. https://doi.org/10.1186/1741-7015-5-5.
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Sermet-Gaudelus, I., Renouil, M., Fajac, A. et al. Correction to: In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med 16, 159 (2018). https://doi.org/10.1186/s12916-018-1138-z