Ainiala H, Loukkola J, Peltola J, Korpela M, Hietaharju A: The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus. Neurology. 2001, 57: 496-500. 10.1212/WNL.57.3.496.
Article
CAS
PubMed
Google Scholar
Brey RL, Holliday SL, Saklad AR, Navarrete MG, Hermosillo-Romo D, Stallworth CL, Valdez CR, Escalante A, del Rincon I, Gronseth G, Rhine CB, Padilla P, McGlasson D: Neuropsychiatric syndromes in lupus: prevalence using standardized definitions. Neurology. 2002, 58: 1214-1220. 10.1212/WNL.58.8.1214.
Article
CAS
PubMed
Google Scholar
Lapteva L, Nowak M, Yarboro CH, Takada K, Roebuck-Spencer T, Weickert T, Bleiberg J, Rosenstein D, Pao M, Patronas N, Steele S, Manzano M, van der Veen JW, Lipsky PE, Marenco S, Wesley R, Volpe B, Diamond B, Illei GG: Anti-N-methyl-D-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus. Arthritis Rheum. 2006, 54: 2505-2514. 10.1002/art.22031.
Article
CAS
PubMed
Google Scholar
Greenwood DL, Gitlits VM, Alderuccio F, Sentry JW, Toh BH: Autoantibodies in neuropsychiatric lupus. Autoimmunity. 2002, 35: 79-86. 10.1080/08916930290016547.
Article
CAS
PubMed
Google Scholar
Borchers AT, Aoki CA, Naguwa SM, Keen CL, Shoenfeld Y, Gershwin ME: Neuropsychiatric features of systemic lupus erythematosus. Autoimmun Rev. 2005, 4: 329-344. 10.1016/j.autrev.2005.01.008.
Article
CAS
PubMed
Google Scholar
The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum. 1999, 42: 599-608.
Rekvig OP, Putterman C, Casu C, Gao HX, Ghirardello A, Mortensen ES, Tincani A, Doria A: Autoantibodies in lupus: culprits or passive bystanders?. Autoimmun Rev. 2012, 11: 596-603. 10.1016/j.autrev.2011.10.021.
Article
PubMed
Google Scholar
Kozora E, Hanly JG, Lapteva L, Filley CM: Cognitive dysfunction in systemic lupus erythematosus: past, present, and future. Arthritis Rheum. 2008, 58: 3286-3298. 10.1002/art.23991.
Article
PubMed
Google Scholar
Kapadia M, Sakic B: Autoimmune and inflammatory mechanisms of CNS damage. Prog Neurobiol. 2011, 95: 301-333. 10.1016/j.pneurobio.2011.08.008.
Article
CAS
PubMed
Google Scholar
Oikonomou KG, Zachou K, Dalekos GN: Alpha-actinin: a multidisciplinary protein with important role in B-cell driven autoimmunity. Autoimmun Rev. 2011, 10: 389-396. 10.1016/j.autrev.2010.12.009.
Article
CAS
PubMed
Google Scholar
Zandman-Goddard G, Chapman J, Shoenfeld Y: Autoantibodies involved in neuropsychiatric SLE and antiphospholipid syndrome. Semin Arthritis Rheum. 2007, 36: 297-315. 10.1016/j.semarthrit.2006.11.003.
Article
CAS
PubMed
Google Scholar
Weiner SM, Klein R, Berg PA: A longitudinal study of autoantibodies against central nervous system tissue and gangliosides in connective tissue diseases. Rheumatol Int. 2000, 19: 83-88. 10.1007/s002960050108.
Article
CAS
PubMed
Google Scholar
Bonfa E, Golombek SJ, Kaufman LD, Skelly S, Weissbach H, Brot N, Elkon KB: Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med. 1987, 317: 265-271. 10.1056/NEJM198707303170503.
Article
CAS
PubMed
Google Scholar
Toubi E, Shoenfeld Y: Clinical and biological aspects of anti-P-ribosomal protein autoantibodies. Autoimmun Rev. 2007, 6: 119-125. 10.1016/j.autrev.2006.07.004.
Article
CAS
PubMed
Google Scholar
Katzav A, Pick CG, Korczyn AD, Oest E, Blank M, Shoenfeld Y, Chapman J: Hyperactivity in a mouse model of the antiphospholipid syndrome. Lupus. 2001, 10: 496-499. 10.1191/096120301678416060.
Article
CAS
PubMed
Google Scholar
DeGiorgio LA, Konstantinov KN, Lee SC, Hardin JA, Volpe BT, Diamond B: A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat Med. 2001, 7: 1189-1193. 10.1038/nm1101-1189.
Article
CAS
PubMed
Google Scholar
Shoenfeld Y, Isenberg DA, Rauch J, Madaio MP, Stollar BD, Schwartz RS: Idiotypic cross-reactions of monoclonal human lupus autoantibodies. J Exp Med. 1983, 158: 718-730. 10.1084/jem.158.3.718.
Article
CAS
PubMed
Google Scholar
Shoenfeld Y, Hsu-Lin SC, Gabriels JE, Silberstein LE, Furie BC, Furie B, Stollar BD, Schwartz RS: Production of autoantibodies by human-human hybridomas. J Clin Invest. 1982, 70: 205-208. 10.1172/JCI110595.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shoenfeld Y, Rauch J, Massicotte H, Datta SK, Andre-Schwartz J, Stollar BD, Schwartz RS: Polyspecificity of monoclonal lupus autoantibodies produced by human-human hybridomas. N Engl J Med. 1983, 308: 414-420. 10.1056/NEJM198302243080802.
Article
CAS
PubMed
Google Scholar
Andre-Schwartz J, Datta SK, Shoenfeld Y, Isenberg DA, Stollar BD, Schwartz RS: Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies. Clin Immunol Immunopathol. 1984, 31: 261-271. 10.1016/0090-1229(84)90246-0.
Article
CAS
PubMed
Google Scholar
Amital-Teplizki H, Avinoach I, Coates AR, Kooperman O, Blank M, Shoenfeld Y: Binding of monoclonal anti-DNA and anti-TB glycolipids to brain tissue. Autoimmunity. 1989, 4: 277-287. 10.3109/08916938909014704.
Article
CAS
PubMed
Google Scholar
Blank M, Shoenfeld Y: The story of the 16/6 idiotype and systemic lupus erythematosus. Isr Med Assoc J. 2008, 10: 37-39.
PubMed
Google Scholar
Isenberg DA, Shoenfeld Y, Madaio MP, Rauch J, Reichlin M, Stollar BD, Schwartz RS: Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet. 1984, 2: 417-422.
Article
CAS
PubMed
Google Scholar
Galeazzi M, Bellisai F, Sebastiani GD, Morozzi G, Marcolongo R, Houssiau F, Cervera R, Levy Y, George J, Sherer Y, Shoenfeld Y: Association of 16/6 and SA1 anti-DNA idiotypes with anticardiolipin antibodies and clinical manifestations in a large cohort of SLE patients. European Concerted Action on the Immunogenetics of SLE. Clin Exp Rheumatol. 1998, 16: 717-720.
CAS
PubMed
Google Scholar
Amital-Teplizki H, Bearman JE, Miele PW, Sukenik S, Shoenfeld Y: A multidimensional autoantibody analysis specifying systemic lupus erythematosus patients with neuropsychiatric symptomatology. Isr J Med Sci. 1992, 28: 422-427.
CAS
PubMed
Google Scholar
Isenberg DA, Collins C: Detection of cross-reactive anti-DNA antibody idiotypes on renal tissue-bound immunoglobulins from lupus patients. J Clin Invest. 1985, 76: 287-294. 10.1172/JCI111959.
Article
CAS
PubMed
PubMed Central
Google Scholar
Isenberg D, Dudeney C, Wojnaruska F, Bhogal BS, Rauch J, Schattner A, Naparstek Y, Duggan D: Detection of cross reactive anti-DNA antibody idiotypes on tissue-bound immunoglobulins from skin biopsies of lupus patients. J Immunol. 1985, 135: 261-264.
CAS
PubMed
Google Scholar
Konikoff F, Isenberg DA, Kooperman O, Kennedy RC, Rauch J, Theodor E, Shoenfeld Y: Common lupus anti-DNA antibody idiotypes in chronic liver diseases. Clin Immunol Immunopathol. 1987, 43: 265-272. 10.1016/0090-1229(87)90134-6.
Article
CAS
PubMed
Google Scholar
Shoenfeld Y, Livne A, Blank M, Argov S, Krup M, Fleishmakher E, Sukenik S, Teplizki H: A human monoclonal anti-DNA antibody derived from a patient with polymyositis having the common lupus 16/6 idiotype. Immunol Lett. 1988, 19: 77-83. 10.1016/0165-2478(88)90123-X.
Article
CAS
PubMed
Google Scholar
Mendlovic S, Brocke S, Shoenfeld Y, Ben-Bassat M, Meshorer A, Bakimer R, Mozes E: Induction of a systemic lupus erythematosus-like disease in mice by a common human anti-DNA idiotype. Proc Natl Acad Sci U S A. 1988, 85: 2260-2264. 10.1073/pnas.85.7.2260.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shoenfeld Y, Mozes E: Pathogenic idiotypes of autoantibodies in autoimmunity: lessons from new experimental models of SLE. FASEB J. 1990, 4: 2646-2651.
CAS
PubMed
Google Scholar
Shoenfeld Y: Idiotypic induction of autoimmunity: a new aspect of the idiotypic network. FASEB J. 1994, 8: 1296-1301.
CAS
PubMed
Google Scholar
Waisman A, Shoenfeld Y, Blank M, Ruiz PJ, Mozes E: The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment. Int Immunol. 1995, 7: 689-696. 10.1093/intimm/7.4.689.
Article
CAS
PubMed
Google Scholar
Shoenfeld Y, Nahum A, Korczyn AD, Dano M, Rabinowitz R, Beilin O, Pick CG, Leider-Trejo L, Kalashnikova L, Blank M, Chapman J: Neuronal-binding antibodies from patients with antiphospholipid syndrome induce cognitive deficits following intrathecal passive transfer. Lupus. 2003, 12: 436-442. 10.1191/0961203303lu409oa.
Article
CAS
PubMed
Google Scholar
Porsolt RD, Bertin A, Jalfre M: Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther. 1977, 229: 327-336.
CAS
PubMed
Google Scholar
Tordera RM, Totterdell S, Wojcik SM, Brose N, Elizalde N, Lasheras B, Del Rio J: Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1). Eur J Neurosci. 2007, 25: 281-290. 10.1111/j.1460-9568.2006.05259.x.
Article
CAS
PubMed
Google Scholar
Dix SL, Aggleton JP: Extending the spontaneous preference test of recognition: evidence of object-location and object-context recognition. Behav Brain Res. 1999, 99: 191-200. 10.1016/S0166-4328(98)00079-5.
Article
CAS
PubMed
Google Scholar
Berry A, Vacirca D, Capoccia S, Bellisario V, Malorni W, Ortona E, Cirulli F: Anti-ATP synthase autoantibodies induce neuronal death by apoptosis and impair cognitive performance in C57BL/6 mice. J Alzheimers Dis. 2013, 33: 317-321.
CAS
PubMed
Google Scholar
Sun KH, Tang SJ, Lin ML, Wang YS, Sun GH, Liu WT: Monoclonal antibodies against human ribosomal P proteins penetrate into living cells and cause apoptosis of Jurkat T cells in culture. Rheumatology (Oxford). 2001, 40: 750-756. 10.1093/rheumatology/40.7.750.
Article
CAS
Google Scholar
Koscec M, Koren E, Wolfson-Reichlin M, Fugate RD, Trieu E, Targoff IN, Reichlin M: Autoantibodies to ribosomal P proteins penetrate into live hepatocytes and cause cellular dysfunction in culture. J Immunol. 1997, 159: 2033-2041.
CAS
PubMed
Google Scholar
Matus S, Burgos PV, Bravo-Zehnder M, Kraft R, Porras OH, Farias P, Barros LF, Torrealba F, Massardo L, Jacobelli S, Gonzalez A: Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis. J Exp Med. 2007, 204: 3221-3234. 10.1084/jem.20071285.
Article
CAS
PubMed
PubMed Central
Google Scholar
Katzav A, Ben-Ziv T, Chapman J, Blank M, Reichlin M, Shoenfeld Y: Anti-P ribosomal antibodies induce defect in smell capability in a model of CNS-SLE (depression). J Autoimmun. 2008, 31: 393-398. 10.1016/j.jaut.2008.09.002.
Article
CAS
PubMed
Google Scholar
Katzav A, Solodeev I, Brodsky O, Chapman J, Pick CG, Blank M, Zhang W, Reichlin M, Shoenfeld Y: Induction of autoimmune depression in mice by anti-ribosomal P antibodies via the limbic system. Arthritis Rheum. 2007, 56: 938-948. 10.1002/art.22419.
Article
CAS
PubMed
Google Scholar
Menachem A, Chapman J, Katzav A: Hyperactivity induced by antiphospholipid syndrome serum. Ann N Y Acad Sci. 2009, 1173: 422-426. 10.1111/j.1749-6632.2009.04876.x.
Article
CAS
PubMed
Google Scholar
Sherer Y, Gorstein A, Fritzler MJ, Shoenfeld Y: Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients. Semin Arthritis Rheum. 2004, 34: 501-537. 10.1016/j.semarthrit.2004.07.002.
Article
CAS
PubMed
Google Scholar
Unterman A, Nolte JE, Boaz M, Abady M, Shoenfeld Y, Zandman-Goddard G: Neuropsychiatric syndromes in systemic lupus erythematosus: a meta-analysis. Semin Arthritis Rheum. 2010, 41: 1-11.
Article
PubMed
Google Scholar
Faust TW, Chang EH, Kowal C, Berlin R, Gazaryan IG, Bertini E, Zhang J, Sanchez-Guerrero J, Fragoso-Loyo HE, Volpe BT, Diamond B, Huerta PT: Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms. Proc Natl Acad Sci U S A. 2010, 107: 18569-18574. 10.1073/pnas.1006980107.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kowal C, DeGiorgio LA, Nakaoka T, Hetherington H, Huerta PT, Diamond B, Volpe BT: Cognition and immunity; antibody impairs memory. Immunity. 2004, 21: 179-188. 10.1016/j.immuni.2004.07.011.
Article
CAS
PubMed
Google Scholar
Kivity S, Tsarfaty G, Agmon-Levin N, Blank M, Manor D, Konen E, Chapman J, Reichlin M, Wasson C, Shoenfeld Y, Kushnir T: Abnormal olfactory function demonstrated by manganese-enhanced MRI in mice with experimental neuropsychiatric lupus. Ann N Y Acad Sci. 2010, 1193: 70-77. 10.1111/j.1749-6632.2009.05302.x.
Article
PubMed
Google Scholar
Shoenfeld Y, Ben-Yehuda O, Messinger Y, Bentwitch Z, Rauch J, Isenberg DI, Gadoth N: Autoimmune diseases other than lupus share common anti-DNA idiotypes. Immunol Lett. 1988, 17: 285-291. 10.1016/0165-2478(88)90043-0.
Article
CAS
PubMed
Google Scholar
Isenberg DA, Shoenfeld Y: An analysis of autoimmunity through studies of DNA antibody idiotypes. Autoimmunity. 1988, 1: 67-75. 10.3109/08916938808997178.
Article
CAS
PubMed
Google Scholar
El-Roiey A, Gross WL, Luedemann J, Isenberg DA, Shoenfeld Y: Preferential secretion of a common anti-DNA idiotype (16/6 Id) and anti-polynucleotide antibodies by normal mononuclear cells following stimulation with Klebsiella pneumoniae. Immunol Lett. 1986, 12: 313-319. 10.1016/0165-2478(86)90036-2.
Article
CAS
PubMed
Google Scholar
Shoenfeld Y, Vilner Y, Coates AR, Rauch J, Lavie G, Shaul D, Pinkhas J: Monoclonal anti-tuberculosis antibodies react with DNA, and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis. Clin Exp Immunol. 1986, 66: 255-261.
CAS
PubMed
PubMed Central
Google Scholar
Kivity S, Agmon-Levin N, Blank M, Shoenfeld Y: Infections and autoimmunity–friends or foes?. Trends Immunol. 2009, 30: 409-414. 10.1016/j.it.2009.05.005.
Article
CAS
PubMed
Google Scholar
Broadbent NJ, Squire LR, Clark RE: Spatial memory, recognition memory, and the hippocampus. Proc Natl Acad Sci U S A. 2004, 101: 14515-14520. 10.1073/pnas.0406344101.
Article
CAS
PubMed
PubMed Central
Google Scholar
Milstone AM, Meyers K, Elia J: Treatment of acute neuropsychiatric lupus with intravenous immunoglobulin (IVIG): a case report and review of the literature. Clin Rheumatol. 2005, 24: 394-397. 10.1007/s10067-004-1046-9.
Article
PubMed
Google Scholar
Mozes E, Sharabi A: A novel tolerogenic peptide, hCDR1, for the specific treatment of systemic lupus erythematosus. Autoimmun Rev. 2010, 10: 22-26. 10.1016/j.autrev.2010.07.004.
Article
CAS
PubMed
Google Scholar
Lapter S, Marom A, Meshorer A, Elmann A, Sharabi A, Vadai E, Neufeld A, Sztainberg Y, Gil S, Getselter D, Chen A, Mozes E: Amelioration of brain pathology and behavioral dysfunction in mice with lupus following treatment with a tolerogenic peptide. Arthritis Rheum. 2009, 60: 3744-3754. 10.1002/art.25013.
Article
CAS
PubMed
Google Scholar
Sthoeger ZM, Sharabi A, Molad Y, Asher I, Zinger H, Dayan M, Mozes E: Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): immunomodulation of gene expression. J Autoimmun. 2009, 33: 77-82. 10.1016/j.jaut.2009.03.009.
Article
CAS
PubMed
Google Scholar