GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioral, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390:1345–422.
Google Scholar
World Health Organization. Global action plan for the prevention and control of noncommunicable diseases 2013-2020. Available from http://www.who.int/nmh/events/ncd_action_plan/en/. Accessed 9 Dec 2018
Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047–53.
PubMed
Google Scholar
International Diabetes Federation. IDF Diabetes atlas. Brussels: International Diabetes Federation; 2017. http://www.diabetesatlas.org/resources/2017-atlas.html. Accessed 1 Dec 2018
Google Scholar
Whiting DR, Guariguata L, Weil C, et al. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract. 2011;94:311–21.
PubMed
Google Scholar
Campbell PT, Newton CC, Patel AV, et al. Diabetes and cause-specific mortality in a prospective cohort of one million U.S. adults. Diabetes Care. 2012;35:1835–44.
PubMed
PubMed Central
Google Scholar
Peters SA, Huxley RR, Woodward M. Diabetes as a risk factor for stroke in women compared with men: a systematic review and meta-analysis of 64 cohorts, including 775,385 individuals and 12,539 strokes. Lancet. 2014;383:1973–80.
PubMed
Google Scholar
Peters SA, Huxley RR, Woodward M. Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 individuals and 28,203 coronary events. Diabetologia. 2014;57:1542–51.
PubMed
Google Scholar
Fang H, Shan S, Zhou Y, et al. Diabetes mellitus and the risk of gastrointestinal cancer in women compared with men: a meta-analysis of cohort studies. BMC Cancer. 2018;18:422.
PubMed
PubMed Central
Google Scholar
Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283:2008–12.
PubMed
CAS
Google Scholar
Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535.
PubMed
PubMed Central
Google Scholar
GA Wells, B Shea, D O'Connell, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. Available from http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. Accessed 9 Dec 2018
Zhang J, Yu KF. What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA. 1998;280:1690–1.
PubMed
CAS
Google Scholar
Huxley RR, Woodward M. Cigarette smoking as a risk factor for coronary heart disease in women compared with men: a systematic review and meta-analysis of prospective cohort studies. Lancet. 2011;378:1297–305.
PubMed
Google Scholar
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539–58.
PubMed
Google Scholar
Sterne JA, Egger M. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol. 2001;54:1046–55.
PubMed
CAS
Google Scholar
Jousilahti P, Vartiainen E, Tuomilehto J, et al. Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation. 1999;99:1165–72.
PubMed
CAS
Google Scholar
Oba S, Nagata C, Nakamura K, et al. Self-reported diabetes mellitus and risk of mortality from all causes, cardiovascular disease, and cancer in Takayama: a population-based prospective cohort study in Japan. J Epidemiol. 2008;18:197–203.
PubMed
PubMed Central
Google Scholar
Hu G, Jousilahti P, Qiao Q, et al. Sex differences in cardiovascular and total mortality among diabetic and non-diabetic individuals with or without history of myocardial infarction. Diabetologia. 2005;48:856–61.
PubMed
CAS
Google Scholar
Madssen E, Vatten L, Nilsen TI, et al. Abnormal glucose regulation and gender-specific risk of fatal coronary artery disease in the HUNT 1 study. Scand Cardiovasc J. 2012;46:219–25.
PubMed
CAS
Google Scholar
DECODE Study Group, the European Diabetes Epidemiology Group. Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. Arch Intern Med. 2001;161:397–405.
Google Scholar
Keil JE, Sutherland SE, Knapp RG, et al. Mortality rates and risk factors for coronary disease in black as compared with white men and women. N Engl J Med. 1993;329:73–8.
PubMed
CAS
Google Scholar
Friberg J, Scharling H, Gadsbøll N, et al. Comparison of the impact of atrial fibrillation on the risk of stroke and cardiovascular death in women versus men (The Copenhagen City Heart Study). Am J Cardiol. 2004;94:889–94.
PubMed
Google Scholar
Collins VR, Dowse GK, Ram P, et al. Non-insulin-dependent diabetes and 11-year mortality in Asian Indian and Melanesian Fijians. Diabet Med. 1996;13:125–32.
PubMed
CAS
Google Scholar
Bozorgmanesh M, Hadaegh F, Sheikholeslami F, et al. Cardiovascular risk and all-cause mortality attributable to diabetes: Tehran lipid and glucose study. J Endocrinol Invest. 2012;35:14–20.
PubMed
CAS
Google Scholar
Kleinman JC, Donahue RP, Harris MI, et al. Mortality among diabetics in a national sample. Am J Epidemiol. 1988;128:389–401.
PubMed
CAS
Google Scholar
Magliano DJ, Söderberg S, Zimmet PZ, et al. Mortality, all-cause and cardiovascular disease, over 15 years in multiethnic mauritius: impact of diabetes and intermediate forms of glucose tolerance. Diabetes Care. 2010;33:1983–9.
PubMed
PubMed Central
Google Scholar
Barrett-Connor EL, Cohn BA, Wingard DL, et al. Why is diabetes mellitus a stronger risk factor for fatal ischemic heart disease in women than in men? The Rancho Bernardo Study. JAMA. 1991;265:627–31.
PubMed
CAS
Google Scholar
Fraser GE, Strahan TM, Sabaté J, et al. Effects of traditional coronary risk factors on rates of incident coronary events in a low-risk population. The Adventist Health Study. Circulation. 1992;86:406–13.
PubMed
CAS
Google Scholar
Sievers ML, Nelson RG, Knowler WC, et al. Impact of NIDDM on mortality and causes of death in Pima Indians. Diabetes Care. 1992;15:1541–9.
PubMed
CAS
Google Scholar
Seeman T, Mendes de Leon C, Berkman L, et al. Risk factors for coronary heart disease among older men and women: a prospective study of community-dwelling elderly. Am J Epidemiol. 1993;138:1037–49.
PubMed
CAS
Google Scholar
Wang WS, Wahlqvist ML, Hsu CC, et al. Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan. BMC Public Health. 2012;12:111.
PubMed
PubMed Central
CAS
Google Scholar
Natarajan S, Liao Y, Cao G, et al. Sex differences in risk for coronary heart disease mortality associated with diabetes and established coronary heart disease. Arch Intern Med. 2003;163:1735–40.
PubMed
Google Scholar
Vilbergsson S, Sigurdsson G, Sigvaldason H, et al. Coronary heart disease mortality amongst non-insulin-dependent diabetic subjects in Iceland: the independent effect of diabetes. The Reykjavik Study 17-year follow up. J Intern Med. 1998;244:309–16.
PubMed
CAS
Google Scholar
Qvist J, Johansson SE, Johansson LM, et al. Multivariate analyses of mortality from coronary heart disease due to biological and behavioural factors. Scand J Soc Med. 1996;24:67–76.
PubMed
CAS
Google Scholar
Tunstall-Pedoe H, Woodward M, Tavendale R, et al. Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish Heart Health Study: cohort study. BMJ. 1997;315:722–9.
PubMed
PubMed Central
CAS
Google Scholar
Nilsson PM, Johansson SE, Sundquist J, et al. Low educational status is a risk factor for mortality among diabetic people. Diabet Med. 1998;15:213–9.
PubMed
CAS
Google Scholar
Imazu M, Sumii K, Yamamoto H, et al. Influence of type 2 diabetes mellitus on cardiovascular disease mortality: findings from the Hawaii-Los Angeles-Hiroshima study. Diabetes Res Clin Pract. 2002;57:61–9.
PubMed
Google Scholar
Hart CL, Hole DJ, Smith GD, et al. Risk factors and 20-year stroke mortality in men and women in the Renfrew/Paisley study in Scotland. Stroke. 1999;30:1999–2007.
PubMed
CAS
Google Scholar
Bragg F, Holmes MV, Iona A, et al. Association Between Diabetes and Cause-Specific Mortality in Rural and Urban Areas of China. JAMA. 2017;317:280–9.
PubMed
PubMed Central
Google Scholar
Kato M, Noda M, Mizoue T, et al. Diagnosed diabetes and premature death among middle-aged Japanese: results from a large-scale population-based cohort study in Japan (JPHC study). BMJ Open. 2015;5:e007736.
PubMed
PubMed Central
Google Scholar
Johansen H, Semenciw R, Morrison H, et al. Important risk factors for death in adults: a 10-year follow-up of the Nutrition Canada survey cohort. CMAJ. 1987;136:823–8.
PubMed
PubMed Central
CAS
Google Scholar
Suemoto CK, Lebrao ML, Duarte YA, et al. Effects of body mass index, abdominal obesity, and type 2 diabetes on mortality in community-dwelling elderly in Sao Paulo, Brazil: analysis of prospective data from the SABE study. J Gerontol A Biol Sci Med Sci. 2015;70:503–10.
PubMed
CAS
Google Scholar
Jee SH, Ohrr H, Sull JW, et al. Fasting serum glucose level and cancer risk in Korean men and women. JAMA. 2005;293:194–202.
PubMed
CAS
Google Scholar
Fraser GE, Shavlik DJ, et al. Risk factors for all-cause and coronary heart disease mortality in the oldest-old. The Adventist Health Study. Arch Intern Med. 1997;157:2249–58.
PubMed
CAS
Google Scholar
Moe B, Eilertsen E, Nilsen TI, et al. The combined effect of leisure-time physical activity and diabetes on cardiovascular mortality: the Nord-Trondelag Health (HUNT) cohort study, Norway. Diabetes Care. 2013;36:690–5.
PubMed
PubMed Central
Google Scholar
Liu L. Social connections, diabetes mellitus, and risk of mortality among white and African-American adults aged 70 and older: an eight-year follow-up study. Ann Epidemiol. 2011;21:26–33.
PubMed
Google Scholar
Vimalananda VG, Biggs ML, Rosenzweig JL, et al. The influence of sex on cardiovascular outcomes associated with diabetes among older black and white adults. J Diabetes Complications. 2014;28:316–22.
PubMed
Google Scholar
Eichner JE, Wang W, Zhang Y, et al. Tobacco use and cardiovascular disease among American Indians: the strong heart study. Int J Environ Res Public Health. 2010;7:3816–30.
PubMed
PubMed Central
Google Scholar
Bozorgmanesh M, Hadaegh F, Sheikholeslami F, et al. Shadow of diabetes over cardiovascular disease: comparative uantification of population-attributable all-cause and cardiovascular mortality. Cardiovasc Diabetol. 2012;11:69.
PubMed
PubMed Central
Google Scholar
Moe B, Augestad LB, Nilsen TI, et al. Diabetes severity and the role of leisure time physical exercise on cardiovascular mortality: the Nord-Trøndelag Health study (HUNT), Norway. Cardiovasc Diabetol. 2013;12:83.
PubMed
PubMed Central
Google Scholar
Kakehi E, Kotani K, Ishikawa S, et al. Relationship between screening plasma glucose concentrations and cancer- and all-cause mortality: the Jichi Medical School(JMS) cohort study. J Public Health. 2014;22:505–11.
Google Scholar
Shen C, Schooling CM, Chan WM, et al. Self-reported diabetes and mortality in a prospective Chinese elderly cohort study in Hong Kong. Prev Med. 2014;64:20–6.
PubMed
Google Scholar
Hiltunen L. Ten-year mortality and glucose tolerance status in an elderly Finnish population. Diabetes Res Clin Pract. 2005;69:81–7.
PubMed
CAS
Google Scholar
Gordon-Dseagu VL, Shelton N, Mindell J, et al. Diabetes mellitus and mortality from all-causes, cancer, cardiovascular and respiratory disease: evidence from the Health Survey for England and Scottish Health Survey cohorts. J Diabetes Complications. 2014;28:791–7.
PubMed
Google Scholar
Yeh HC, Platz EA, Wang NY, et al. A prospective study of the associations between treated diabetes and cancer outcomes. Diabetes Care. 2012;35:113–8.
PubMed
Google Scholar
Chen Y, Wu F, Saito E, et al. Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium. Diabetologia. 2017;60:1022–32.
PubMed
PubMed Central
Google Scholar
Zhou XH, Qiao Q, Zethelius B, et al. Diabetes, prediabetes and cancer mortality. Diabetologia. 2010;53:1867–76.
PubMed
CAS
Google Scholar
Drake I, Gullberg B, Sonestedt E, et al. Type 2 diabetes, adiposity and cancer morbidity and mortality risk taking into account competing risk of noncancer deaths in a prospective cohort setting. Int J Cancer. 2017;141:1170–80.
PubMed
PubMed Central
CAS
Google Scholar
Preis SR, Hwang SJ, Coady S, et al. Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005. Circulation. 2009;119:1728–35.
PubMed
PubMed Central
Google Scholar
Natarajan S, Liao Y, Sinha D, et al. Sex differences in the effect of diabetes duration on coronary heart disease mortality. Arch Intern Med. 2005;165:430–5.
PubMed
Google Scholar
Hirakawa Y, Ninomiya T, Kiyohara Y, et al. Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN). J Epidemiol. 2017;27:123–9.
PubMed
PubMed Central
Google Scholar
Alegre-Díaz J, Herrington W, López-Cervantes M, et al. Diabetes and Cause-Specific Mortality in Mexico City. N Engl J Med. 2016;375:1961–71.
PubMed
PubMed Central
Google Scholar
Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Framingham study. JAMA. 1979;241:2035–8.
PubMed
CAS
Google Scholar
Harris MI, Director. Diabetes in america, 2nd edition. Diabetes Res Clin Pr 1995;30:75
Regensteiner JG, Golden S, Huebschmann AG, et al. Sex differences in the cardiovascular consequences of diabetes mellitus: a scientific statement from the american heart association. Circulation. 2015;132:2424.
PubMed
Google Scholar
Ostan R, Monti D, Gueresi P, et al. Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicine. Clin Sci (Lond). 2016;130:1711–25.
Google Scholar
Gouni-Berthold I, Berthold HK, Mantzoros CS, et al. Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes. Diabetes Care. 2008;31:1389–91.
PubMed
PubMed Central
Google Scholar
Barrettconnor E. Sex differences in coronary heart disease why are women so superior? The 1995 Ancel Keys Lecture. Circulation. 1997;95:252–64.
CAS
Google Scholar
Zeller T, Schnabel RB, Appelbaum S, et al. Low testosterone levels are predictive for incident atrial fibrillation and ischaemic stroke in men, but protective in women - results from the finrisk study. Eur J Prev Cardiol. 2018;25:1133–9.
PubMed
Google Scholar
Robert A, Kloner MD, Culley Carson III, et al. Testosterone and Cardiovascular Disease. JACC. 2016;67:545–57.
Google Scholar
BarrettConnor E. The rancho bernardo study: 40 years studying why women have less heart disease than men and how diabetes modifies women's usual cardiac protection. Glob Heart. 2013;8:95–104.
Google Scholar
Basaria S, Coviello AD, Travison TG, et al. Adverse events associated with testosterone administration. N Engl J Med. 2010;363:109–22.
PubMed
PubMed Central
CAS
Google Scholar
Celismorales CA, Welsh P, Lyall DM, et al. Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million uk biobank participants. BMJ. 2018;361:k1651.
Google Scholar
Ogden CL, Carroll MD, Kit BK, et al. Prevalence of childhood and adult obesity in the united states, 2011-2012. JAMA. 2014;311:806.
PubMed
PubMed Central
CAS
Google Scholar
Go AS, Mozaffarian D, Roger VL, et al. Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation. 2013;127:143–52.
PubMed
Google Scholar
Franzini L, Ardigo D, Cavalot F, et al. Women show worse control of type 2 diabetes and cardiovascular disease risk factors than men: results from the MIND.IT Study Group of the Italian Society of Diabetology. Nutr Metab Cardiovasc Dis. 2013;23:235–41.
PubMed
CAS
Google Scholar
Gnatiuc L, Herrington WG, Halsey J, et al. Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980 793 adults from 68 prospective studies. Lancet Diabetes Endocrinol. 2018;6:538–46.
Google Scholar
Huang Y, Cai X, Mai W, et al. Association between prediabetes and risk of cardiovascular disease and all-cause mortality: systematic review and meta-analysis. BMJ. 2016;355:i5953.
PubMed
PubMed Central
Google Scholar
Donahue RP, Rejman K, Rafalson LB, et al. Sex differences in endothelial function markers before conversion to pre-diabetes: does the clock start ticking earlier among women? The Western New York Study. Diabetes Care. 2007;30:354–9.
PubMed
Google Scholar
Haffner SM, Miettinen H, Stern MP. Relatively more atherogenic coronary heart disease risk factors, in prediabetic women than in prediabetic men. Diabetologia. 1997;40:711–7.
PubMed
CAS
Google Scholar
Hyun KK, Redfern J, Patel A, et al. Gender inequalities in cardiovascular risk factor assessment and management in primary healthcare. Heart. 2017;103:492–8.
PubMed
Google Scholar
Winston GJ, Barr RG, Carrasquillo O, et al. Sex and racial/ethnic differences in cardiovascular disease risk factor treatment and control among individuals with diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2009;32:1467–9.
PubMed
PubMed Central
CAS
Google Scholar
Krämer HU, Elke R, Gernot R, et al. Gender disparities in diabetes and coronary heart disease medication among patients with type 2 diabetes: results from the Diana study. Cardiovasc Diabetol. 2012;11:88.
PubMed
PubMed Central
Google Scholar
Manteuffel M, Williams S, Chen W, et al. Influence of patient sex and gender on medication use, adherence, and prescribing alignment with guidelines. J Womens Health(Larchmt). 2014;21:112–9.
Google Scholar
Cenko E, Yoon J, Kedev S, et al. Sex differences in outcomes after stemi: effect modification by treatment strategy and age. JAMA Intern Med. 2018;178:632–9.
PubMed
PubMed Central
Google Scholar
Bugiardini R, Ricci B, Cenko E, et al. Delayed care and mortality among women and men with myocardial infarction. J Am Heart Assoc. 2017;6:e005968.
PubMed
PubMed Central
Google Scholar
Dwyer-Lindgren L, Mackenbach JP, van Lenthe FJ, et al. Diagnosed and Undiagnosed Diabetes Prevalence by County in the U.S., 1999-2012. Diabetes Care. 2016;39:1556–62.
PubMed
Google Scholar
Muntoni S, Atzori L, Mereu R, et al. Prevalence of diagnosed and undiagnosed diabetes mellitus and impaired fasting glucose in Sardinia. Acta Diabetol. 2009;46:227–31.
PubMed
CAS
Google Scholar
Tsilidis KK, Kasimis JC, Lopez DS, et al. Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies. BMJ. 2015;350:g7607.
PubMed
Google Scholar
Ge Z, Ben Q, Qian J, et al. Diabetes mellitus and risk of gastric cancer: a systematic review and meta-analysis of observational studies. Eur J Gastroenterol Hepatol. 2011;23:1127–35.
PubMed
CAS
Google Scholar
Larsson SC. Diabetes mellitus and incidence of kidney cancer: a meta-analysis of cohort studies. Diabetologia. 2011;54:1013–8.
PubMed
CAS
Google Scholar
Huang W, Ren H, Ben Q, et al. Risk of esophageal cancer in diabetes mellitus: a meta-analysis of observational studies. Cancer Causes Control. 2012;23:263–72.
PubMed
Google Scholar
Castillo JJ, Mull N, Reagan JL, et al. Increased incidence of non-hodgkin lymphoma, leukemia, and myeloma in patients with diabetes mellitus type 2: a meta-analysis of observational studies. Blood. 2012;119:4845–50.
PubMed
PubMed Central
CAS
Google Scholar
Seshasai SRK, Kaptoge S, Thompson A, et al. Diabetes mellitus, fasting glucose, and risk of cause-specific death. N Engl J Med. 2011;364:829.
CAS
Google Scholar