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Articles
951 result(s) for 'alcohol' within BMC Medicine
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Citation: BMC Medicine 2023 21:228
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Trends in mortality from alcohol, opioid, and combined alcohol and opioid poisonings by sex, educational attainment, and race and ethnicity for the United States 2000–2019
The ongoing opioid epidemic and increases in alcohol-related mortality are key public health concerns ... in sex-specific mortality rates for opioid, alcohol, and combined alcohol and opioid poisonings in the USA...
Citation: BMC Medicine 2022 20:405 -
Association between patterns of alcohol consumption (beverage type, frequency and consumption with food) and risk of adverse health outcomes: a prospective cohort study
Alcohol consumption is a leading contributor to death ... not examined the effects of different patterns of alcohol consumption. The study objective was to understand the relationship between different alcohol co...
Citation: BMC Medicine 2021 19:8 -
Effectiveness of genetic feedback on alcohol metabolism to reduce alcohol consumption in young adults: an open-label randomized controlled trial
It is unclear whether brief interventions using the combined classification of alcohol-metabolizing enzymes aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) together with behavioral changes i...
Citation: BMC Medicine 2024 22:205 -
Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank
The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial...
Citation: BMC Medicine 2023 21:509 -
Why does society accept a higher risk for alcohol than for other voluntary or involuntary risks?
Societies tend to accept much higher risks for voluntary behaviours, those based on individual decisions (for example, to smoke, to consume alcohol, or to ski), than for involuntary ... However, drinking more tha...
Citation: BMC Medicine 2014 12:189 -
Modest alcohol intake and mortality in individuals with elevated alanine aminotransferase levels: a nationwide cohort study
Alanine aminotransferase (ALT) levels are widely used to screen liver disease, and many asymptomatic individuals show elevated ALT levels. As elevated ALT level indicates liver injury, even a small amount of alcohol
Citation: BMC Medicine 2022 20:18 -
Video Q & A: Alcohol - a global problem. An interview with Ian Gilmore
In this video Q & A, we talk to Ian Gilmore about the global burden of alcohol in terms of its scale, and its...
Citation: BMC Medicine 2014 12:209 -
The impact of alcohol taxation increase on all-cause mortality inequalities in Lithuania: an interrupted time series analysis
Taxation increases which reduce the affordability of alcohol are expected to reduce mortality inequalities. A...
Citation: BMC Medicine 2023 21:22 -
Alcohol consumption and hepatocellular carcinoma: novel insights from a prospective cohort study and nonlinear Mendelian randomization analysis
Participants from the UK Biobank with detailed information on alcohol use and free of common diseases were included. Daily pure alcohol intake (g/day) was calculated, and ... analyses were performed to evaluate t...
Citation: BMC Medicine 2022 20:413 -
Estimated projection of incidence and mortality of alcohol-related liver disease in China from 2022 to 2040: a modeling study
China has one of the highest numbers of liver disease cases in the world, including 6.4 million cirrhosis associated with alcohol-related liver disease (ALD) cases. However ... lack of urgent awareness about the ...
Citation: BMC Medicine 2023 21:277 -
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders
Prenatal alcohol exposure (PAE) affects embryonic development, causing a variable fetal alcohol spectrum disorder (FASD) phenotype with neuronal ... and birth defects. We hypothesize that early alcohol-induced ep...
Citation: BMC Medicine 2022 20:495 -
Alcohol exposure before and during pregnancy is associated with reduced fetal growth: the Safe Passage Study
Prenatal alcohol exposure (PAE) is a worldwide public ... study investigated the association between periconceptional and prenatal alcohol exposure and longitudinal fetal growth, focusing on...
Citation: BMC Medicine 2023 21:318 -
Alcohol drinking and risks of liver cancer and non-neoplastic chronic liver diseases in China: a 10-year prospective study of 0.5 million adults
Alcohol consumption is an important risk factor for ... relevance to disease risk of drinking patterns and alcohol tolerability, which differ appreciably between Chinese and...
Citation: BMC Medicine 2021 19:216 -
The cost-effectiveness of increasing alcohol taxes: a modelling study
Excessive alcohol use increases risks of chronic diseases such ... of quality of life and life-years. Alcohol taxes can be considered as a public ... they are known to be able to decrease alcohol consumption. In ...
Citation: BMC Medicine 2008 6:36 -
Alcohol consumption and all-cause and cause-specific mortality among US adults: prospective cohort study
Previous studies have shown inconsistent findings regarding the association of light to moderate alcohol consumption with cause-specific mortality. Therefore, ... study sought to examine the prospective associati...
Citation: BMC Medicine 2023 21:208 -
Alcohol consumption, drinking patterns, and ischemic heart disease: a narrative review of meta-analyses and a systematic review and meta-analysis of the impact of heavy drinking occasions on risk for moderate drinkers
Alcohol consumption is a major global risk factor ... the diverse findings on the complex relationship between alcohol consumption and the leading cause of death...
Citation: BMC Medicine 2014 12:182 -
Alcohol intake, wine consumption and the development of depression: the PREDIMED study
Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and i...
Citation: BMC Medicine 2013 11:192 -
Effect of provision of non-alcoholic beverages on alcohol consumption: a randomized controlled study
The use of alcohol-flavored beverages not containing alcohol (hereinafter referred to as non-alcoholic beverages) is recommended to reduce alcohol consumption. However, it is unclear if...
Citation: BMC Medicine 2023 21:379 -
Circulating metabolites may illustrate relationship of alcohol consumption with cardiovascular disease
Metabolite signatures of long-term alcohol consumption are lacking. To better understand the molecular basis linking alcohol drinking and cardiovascular disease (CVD), we investigated circulating metabolites asso...
Citation: BMC Medicine 2023 21:443 -
An exploration of the dynamic longitudinal relationship between mental health and alcohol consumption: a prospective cohort study
Despite intense investigation, the temporal sequence between alcohol consumption and mental health remains unclear. This study explored the relationship between alcohol consumption and mental health over multiple...
Citation: BMC Medicine 2014 12:91 -
The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study
Three birth cohorts, including 65,510 mother/offspring pairs (N...= 562 CHD cases) were included. We used Mendelian randomisation (MR) analyses to explore the effects of genetically predicted maternal body mass i...
Citation: BMC Medicine 2023 21:35 -
Functional connectivity of cognition-related brain networks in adults with fetal alcohol syndrome
Fetal alcohol syndrome (FAS) can result in cognitive ... reported in children and adolescents prenatally exposed to alcohol. Previous reports varied substantially regarding the exact...
Citation: BMC Medicine 2023 21:496 -
Association of alcohol consumption with morbidity and mortality in patients with cardiovascular disease: original data and meta-analysis of 48,423 men and women
Light-to-moderate alcohol consumption has been reported to be cardio- ... with disease. To examine the association between alcohol consumption and prognosis in individuals with pre-...
Citation: BMC Medicine 2021 19:167 -
The dose-response relationship between socioeconomic deprivation and alcohol-attributable mortality risk—a systematic review and meta-analysis
Individuals with low socioeconomic status (SES) experience a higher risk of mortality, in general, and alcohol-attributable mortality in particular. However, a ... between the level of socioeconomic deprivation a...
Citation: BMC Medicine 2021 19:268 -
Clustering care pathways of people with alcohol dependence using a data linkage of routine data in Bremen, Germany
Although many individuals with alcohol dependence (AD) are recognized in the...
Citation: BMC Medicine 2024 22:219 -
Effectiveness of a digital intervention versus alcohol information for online help-seekers in Sweden: a randomised controlled trial
The ubiquity of Internet connectivity, and widespread unmet needs, requires investigations of digital interventions for people seeking help with their drinking. The objective of this study was to test the effecti...
Citation: BMC Medicine 2022 20:176 -
The UK Coronavirus Job Retention Scheme and smoking, alcohol consumption and vaping during the COVID-19 pandemic: evidence from eight longitudinal population surveys
Employment disruptions can impact smoking and alcohol consumption. During the COVID-19 pandemic, ... furlough was associated with smoking, vaping and alcohol consumption in the UK.
Citation: BMC Medicine 2022 20:345 -
Alcohol and stroke: the splitters win again
Study of the relationships of alcohol drinking and risk of stroke can readily ... intracerebral hemorrhage, and ischemic stroke, finding disparate alcohol–stroke relationships. Our Commentary pursues the disparit...
Citation: BMC Medicine 2016 14:193 -
E-cigarette use and relations to tobacco and alcohol use among adolescents
Electronic cigarette (EC) use is currently subject to a debate concerning safety, regulation need, and probable contribution to smoking cessation. An important gap in this debate is the lack of distinction betwee...
Citation: BMC Medicine 2015 13:103 -
The socioeconomic profile of alcohol-attributable mortality in South Africa: a modelling study
Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a ... this study w...
Citation: BMC Medicine 2018 16:97 -
Differing association of alcohol consumption with different stroke types: a systematic review and meta-analysis
Whether light-to-moderate alcohol consumption is protective against stroke, and whether ... to summarize the evidence from prospective studies on alcohol drinking and stroke types.
Citation: BMC Medicine 2016 14:178 -
Quantifying harms to others due to alcohol consumption in Germany: a register-based study
The consumption of alcohol increases the risk of drinkers harming others. The extent of alcohol’s morbidity and mortality harms to others ... in 2014 was estimated for (1) fetal alcohol syndrome (FAS) or fetal alcohol
Citation: BMC Medicine 2019 17:59 -
Can public health policies on alcohol and tobacco reduce a cancer epidemic? Australia's experience
Although long-term alcohol and tobacco use have widely been recognised ... risk factors for cancer, the impacts of alcohol and tobacco health policies on cancer mortality ... study aims to estimate the associatio...
Citation: BMC Medicine 2019 17:213 -
Holidays, celebrations, and commiserations: measuring drinking during feasting and fasting to improve national and individual estimates of alcohol consumption
Accurate measures of alcohol consumption are critical in assessing health harms caused by alcohol. In many countries, there are large ... based measures of consumption and those based on alcohol sales. In England...
Citation: BMC Medicine 2015 13:113 -
Life course trajectories of alcohol consumption in the United Kingdom using longitudinal data from nine cohort studies
Alcohol consumption patterns change across life and this ... data. Analysis of longitudinal data, with repeat alcohol measures, is necessary to reveal changes within ... of the life course. Therefore, we examined...
Citation: BMC Medicine 2015 13:47 -
Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European Union
Hazardous and harmful alcohol use and high blood pressure are central ... and interventions for hypertension and hazardous and harmful alcohol use in primary healthcare can contribute substantially...
Citation: BMC Medicine 2017 15:173 -
Twenty-year trajectories of alcohol consumption during midlife and atherosclerotic thickening in early old age: findings from two British population cohort studies
Epidemiological evidence indicates a protective effect of light-moderate drinking on cardiovascular disease and an increased risk for heavier drinking. Nevertheless, the effect of alcohol on atherosclerotic chang...
Citation: BMC Medicine 2016 14:111 -
Association of longitudinal alcohol consumption trajectories with coronary heart disease: a meta-analysis of six cohort studies using individual participant data
Studies have shown that alcohol intake trajectories differ in their associations with ... , we evaluated the association between long-term alcohol consumption trajectories and CHD.
Citation: BMC Medicine 2018 16:124 -
Evaluation in alcohol use disorders – insights from the nalmefene experience
Nalmefene was the first treatment approved by the European Medicines Agency for reducing alcohol consumption in adult patients with alcohol dependence. It is often presented as a ... This experience reveals weakn...
Citation: BMC Medicine 2016 14:119 -
Polygenic risk score-based phenome-wide association study of head and neck cancer across two large biobanks
We revealed the HNSCC PRS showed significant association with phenotypes related to tobacco use disorder (OR, 1.06; 95% CI, 1.05–1.08; P = 3.50 × 10−15), alcoholism (OR, 1.06; 95% CI, 1.04–1.09; P = 6.14 × 10-9),...
Citation: BMC Medicine 2024 22:120 -
Gut and bladder fermentation syndromes: a narrative review
We recently reported the first clinical case of bladder fermentation syndrome (BFS) or urinary auto-brewery syndrome, which caused the patient to fail abstinence monitoring. In BFS, ethanol is generated by Cra...
Citation: BMC Medicine 2024 22:26 -
Association of healthy lifestyle score with all-cause mortality and life expectancy: a city-wide prospective cohort study of cancer survivors
This prospective cohort study included 46,120 surviving patients who were firstly diagnosed with cancer in Guangzhou. Five low-risk lifestyle factors including never smoking, never alcohol use, regular physical a...
Citation: BMC Medicine 2021 19:158 -
Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis
Liver cirrhosis is a major yet largely preventable and underappreciated cause of global health loss. Variations in cirrhosis mortality at the country level reflect differences in prevalence of risk factors such a...
Citation: BMC Medicine 2014 12:145 -
Lifestyle risk factors and residual life expectancy at age 40: a German cohort study
Cigarette smoking, adiposity, unhealthy diet, heavy alcohol drinking and physical inactivity together are associated...
Citation: BMC Medicine 2014 12:59 -
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa)
Guidance to improve fertility includes reducing alcohol and caffeine consumption, achieving healthy weight-range...
Citation: BMC Medicine 2023 21:125 -
The global burden of liver disease: a challenge for methods and for public health
Cirrhosis is a disease of rich and poor alike; key public health risk factors such as alcohol consumption play an important role. Risk-reduction strategies such as controlling the price of alcohol are being widel...
Citation: BMC Medicine 2014 12:159 -
The role of diet in renal cell carcinoma incidence: an umbrella review of meta-analyses of observational studies
Twenty-nine meta-analyses were obtained after screening. After excluding 7 overlapping meta-analyses, 22 meta-analyses including 502 individual studies and 64 summary hazard ratios for RCC incidence were inclu...
Citation: BMC Medicine 2022 20:39 -
Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study
Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually ... weight, physical activity, non-smoking, limited alcohol consumption and a healthy diet, and to....
Citation: BMC Medicine 2014 12:168 -
The effect of acetaminophen (four grams a day for three consecutive days) on hepatic tests in alcoholic patients – a multicenter randomized study
Hepatic failure has been associated with reported therapeutic use of acetaminophen by alcoholic patients. The highest risk period for alcoholic patients is immediately after discontinuation of alcohol intake. Thi...
Citation: BMC Medicine 2007 5:13
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