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The ongoing opioid epidemic and increases in alcohol-related mortality are key public health concerns ... in sex-specific mortality rates for opioid, alcohol, and combined alcohol and opioid poisonings in the USA...
Alcohol consumption is a leading contributor to death ... not examined the effects of different patterns of alcohol consumption. The study objective was to understand the relationship between different alcohol co...
Societies tend to accept much higher risks for voluntary behaviours, those based on individual decisions (for example, to smoke, to consume alcohol, or to ski), than for involuntary ... However, drinking more tha...
Alanine aminotransferase (ALT) levels are widely used to screen liver disease, and many asymptomatic individuals show elevated ALT levels. As elevated ALT level indicates liver injury, even a small amount of alcohol
In this video Q & A, we talk to Ian Gilmore about the global burden of alcohol in terms of its scale, and its...
Taxation increases which reduce the affordability of alcohol are expected to reduce mortality inequalities. A...
Participants from the UK Biobank with detailed information on alcohol use and free of common diseases were included. Daily pure alcohol intake (g/day) was calculated, and ... analyses were performed to evaluate t...
Prenatal alcohol exposure (PAE) affects embryonic development, causing a variable fetal alcohol spectrum disorder (FASD) phenotype with neuronal ... and birth defects. We hypothesize that early alcohol-induced ep...
Alcohol consumption is an important risk factor for ... relevance to disease risk of drinking patterns and alcohol tolerability, which differ appreciably between Chinese and...
Excessive alcohol use increases risks of chronic diseases such ... of quality of life and life-years. Alcohol taxes can be considered as a public ... they are known to be able to decrease alcohol consumption. In ...
Alcohol consumption is a major global risk factor ... the diverse findings on the complex relationship between alcohol consumption and the leading cause of death...
Alcoholic beverages are widely consumed. Depression, the most prevalent mental disorder worldwide, has been related to alcohol intake. We aimed to prospectively assess the association between alcohol intake and i...
Despite intense investigation, the temporal sequence between alcohol consumption and mental health remains unclear. This study explored the relationship between alcohol consumption and mental health over multiple...
Three birth cohorts, including 65,510 mother/offspring pairs (N...= 562 CHD cases) were included. We used Mendelian randomisation (MR) analyses to explore the effects of genetically predicted maternal body mass i...
Light-to-moderate alcohol consumption has been reported to be cardio- ... with disease. To examine the association between alcohol consumption and prognosis in individuals with pre-...
Individuals with low socioeconomic status (SES) experience a higher risk of mortality, in general, and alcohol-attributable mortality in particular. However, a ... between the level of socioeconomic deprivation a...
The ubiquity of Internet connectivity, and widespread unmet needs, requires investigations of digital interventions for people seeking help with their drinking. The objective of this study was to test the effecti...
Employment disruptions can impact smoking and alcohol consumption. During the COVID-19 pandemic, ... furlough was associated with smoking, vaping and alcohol consumption in the UK.
Study of the relationships of alcohol drinking and risk of stroke can readily ... intracerebral hemorrhage, and ischemic stroke, finding disparate alcohol–stroke relationships. Our Commentary pursues the disparit...
Electronic cigarette (EC) use is currently subject to a debate concerning safety, regulation need, and probable contribution to smoking cessation. An important gap in this debate is the lack of distinction betwee...
Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a ... this study w...
Whether light-to-moderate alcohol consumption is protective against stroke, and whether ... to summarize the evidence from prospective studies on alcohol drinking and stroke types.
The consumption of alcohol increases the risk of drinkers harming others. The extent of alcohol’s morbidity and mortality harms to others ... in 2014 was estimated for (1) fetal alcohol syndrome (FAS) or fetal alcohol
Although long-term alcohol and tobacco use have widely been recognised ... risk factors for cancer, the impacts of alcohol and tobacco health policies on cancer mortality ... study aims to estimate the associatio...
Accurate measures of alcohol consumption are critical in assessing health harms caused by alcohol. In many countries, there are large ... based measures of consumption and those based on alcohol sales. In England...
Alcohol consumption patterns change across life and this ... data. Analysis of longitudinal data, with repeat alcohol measures, is necessary to reveal changes within ... of the life course. Therefore, we examined...
Hazardous and harmful alcohol use and high blood pressure are central ... and interventions for hypertension and hazardous and harmful alcohol use in primary healthcare can contribute substantially...
Epidemiological evidence indicates a protective effect of light-moderate drinking on cardiovascular disease and an increased risk for heavier drinking. Nevertheless, the effect of alcohol on atherosclerotic chang...
Studies have shown that alcohol intake trajectories differ in their associations with ... , we evaluated the association between long-term alcohol consumption trajectories and CHD.
Nalmefene was the first treatment approved by the European Medicines Agency for reducing alcohol consumption in adult patients with alcohol dependence. It is often presented as a ... This experience reveals weakn...
This prospective cohort study included 46,120 surviving patients who were firstly diagnosed with cancer in Guangzhou. Five low-risk lifestyle factors including never smoking, never alcohol use, regular physical a...
Liver cirrhosis is a major yet largely preventable and underappreciated cause of global health loss. Variations in cirrhosis mortality at the country level reflect differences in prevalence of risk factors such a...
Cigarette smoking, adiposity, unhealthy diet, heavy alcohol drinking and physical inactivity together are associated...
Guidance to improve fertility includes reducing alcohol and caffeine consumption, achieving healthy weight-range...
Cirrhosis is a disease of rich and poor alike; key public health risk factors such as alcohol consumption play an important role. Risk-reduction strategies such as controlling the price of alcohol are being widel...
Twenty-nine meta-analyses were obtained after screening. After excluding 7 overlapping meta-analyses, 22 meta-analyses including 502 individual studies and 64 summary hazard ratios for RCC incidence were inclu...
Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually ... weight, physical activity, non-smoking, limited alcohol consumption and a healthy diet, and to....
Hepatic failure has been associated with reported therapeutic use of acetaminophen by alcoholic patients. The highest risk period for alcoholic patients is immediately after discontinuation of alcohol intake. Thi...
Eighty-nine studies were identified; 62 US and 18 Scandinavian. Forty-six (52%) controlled for smoking. Random-effects meta-analysis estimates for most sites showed little association. Smoking-adjusted estimat...
Substances, such as alcohol, opiates and cannabis, have been used ... altered to prevent serious harm - one for alcohol and one for cannabis. In the case of alcohol, the addition of dissolved oxygen could reduce ...
Adverse childhood experiences (ACEs) are negatively associated with a range of child health outcomes. In this study, we explored associations between five individual ACEs and child mental health diagnoses or symp...
The impact of mental disorders among homeless people is likely to be substantial in low income countries because of underdeveloped social welfare and health systems. As a first step towards advocacy and provision...
UK Biobank recruited > 500,000 participants, aged 37–73, between 2006 and 2010. Health indicators examined were 81 cancer and 443 non-cancer illnesses used to classify participants' health status; long-standing i...
There is now evolving data exploring the relationship between depression and various individual lifestyle factors such as diet, physical activity, sleep, alcohol intake, and tobacco smoking. While this...
Smokeless tobacco (ST) is consumed by more than 300 million people worldwide. The distribution, determinants and health risks of ST differ from that of smoking; hence, there is a need to highlight its distinct...
The Mediterranean diet has been linked to a number of health benefits, including reduced mortality risk and lower incidence of cardiovascular disease. Definitions of the Mediterranean diet vary across some set...
Within the UK Biobank, 416,481 gout-free participants (aged 37–74) were identified at baseline. Polygenic risk for gout was assessed and categorized as low (lowest tertile), middle (tertile 2), and high (highest ...
The forthcoming post-Millennium Development Goals era will bring about new challenges in global health. Low- and middle-income countries will have to contend with a dual burden of infectious and non-communicab...
Stigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. Ho...
Data were collected between January 2009 and March 2013 from 90 refugee camps across 15 LMIC. Visits to primary care settings were recorded for seven MNS categories: epilepsy/seizure; alcohol/substance use; menta...
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