Berk M, Kapczinski F, Andreazza AC, Dean OM, Giorlando F, Maes M, Yucel M, Gama CS, Dodd S, Dean B, Magalhães PV, Amminger P, McGorry P, Malhi GS: Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci Biobehav Rev. 2011, 35: 804-817. 10.1016/j.neubiorev.2010.10.001.
Article
CAS
PubMed
Google Scholar
Malhi GS, Adams D, Berk M: Is lithium in a class of its own? A brief profile of its clinical use. Aust N Z J Psychiatry. 2009, 43: 1096-1104. 10.3109/00048670903279937.
Article
PubMed
Google Scholar
Ng F, Hallam K, Lucas N, Berk M: The role of lamotrigine in the management of bipolar disorder. Neuropsychiatr Dis Treat. 2007, 3: 463-474.
CAS
PubMed
PubMed Central
Google Scholar
Malhi GS, Berk M, Bourin M, Ivanovski B, Dodd S, Lagopoulos J, Mitchell PB: A typical mood stabilizers: a "typical role for atypical antipsychotics. Acta Psychiatr Scand Suppl. 2005, 29-38. 426
Efrati S, Averbukh M, Berman S, Feldman L, Dishy V, Kachko L, Weissgarten J, Golik A, Averbukh Z: N-Acetylcysteine ameliorates lithium-induced renal failure in rats. Nephrol Dial Transplant. 2005, 20: 65-70. 10.1093/ndt/gfh573.
Article
CAS
PubMed
Google Scholar
Gawryluk JW, Wang JF, Andreazza AC, Shao L, Young LT: Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. Int J Neuropsychopharmacol. 2011, 14: 123-130. 10.1017/S1461145710000805.
Article
CAS
PubMed
Google Scholar
Dean O, Bush AI, Berk M, Copolov DL, van den Buuse M: Glutathione depletion in the brain disrupts short-term spatial memory in the Y-maze in rats and mice. Behav Brain Res. 2009, 198: 258-262. 10.1016/j.bbr.2008.11.017.
Article
CAS
PubMed
Google Scholar
Dean OM, van den Buuse M, Berk M, Copolov DL, Mavros C, Bush AI: N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder. Neurosci Lett. 2011, 499: 149-153. 10.1016/j.neulet.2011.05.027.
Article
CAS
PubMed
Google Scholar
Dean O, Giorlando F, Berk M: N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. J Psychiatry Neurosci. 2011, 36: 78-86.
Article
PubMed
PubMed Central
Google Scholar
Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS: The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial. J Affect Disord. 2011, 135: 389-394. 10.1016/j.jad.2011.06.005.
Article
CAS
PubMed
Google Scholar
Das I, Khan NS, Puri BK, Sooranna SR, de Belleroche J, Hirsch SR: Elevated platelet calcium mobilization and nitric oxide synthase activity may reflect abnormalities in schizophrenic brain. Biochem Biophys Res Commun. 1995, 212: 375-380. 10.1006/bbrc.1995.1980.
Article
CAS
PubMed
Google Scholar
Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC: The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998, 22-33. quiz 34-57, 59 Suppl 20.
Montgomery SA, Asberg M: A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979, 134: 382-389. 10.1192/bjp.134.4.382.
Article
CAS
PubMed
Google Scholar
Berk M, Malhi GS, Cahill C, Carman AC, Hadzi-Pavlovic D, Hawkins MT, Tohen M, Mitchell PB: The Bipolar Depression Rating Scale (BDRS): its development, validation and utility. Bipolar Disord. 2007, 9: 571-579. 10.1111/j.1399-5618.2007.00536.x.
Article
PubMed
Google Scholar
Young RC, Biggs JT, Ziegler VE, Meyer DA: A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978, 133: 429-435. 10.1192/bjp.133.5.429.
Article
CAS
PubMed
Google Scholar
Guy W: ECDEU Assessment Manual for Psychopharmacology. 1976, Rockville, MD: U.S. Department of Health
Google Scholar
Bernardo M, Dodd S, Gama CS, Copolov DL, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Bush AI, Berk M: Effects of N-acetylcysteine on substance use in bipolar disorder: a randomized placebo controlled clinical trial. Acta Neuropsychiatrica. 2009, 21: 239-245. 10.1111/j.1601-5215.2009.00415.x.
Article
PubMed
Google Scholar
Spearing MK, Post RM, Leverich GS, Brandt D, Nolen W: Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP. Psychiatry Res. 1997, 73: 159-171. 10.1016/S0165-1781(97)00123-6.
Article
CAS
PubMed
Google Scholar
Guy W: ECDEU Assessment Manual for Psychopharmacology, Revised. 1976, Washington DC: US Department of Health, Education, and Welfare, 76-338.
Google Scholar
American Psychiatric Association: DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. 2000, Washington D.C.: American Psychiatric Association, 4
Google Scholar
Goldman HH, Skodol AE, Lave TR: Revising axis V for DSM-IV: a review of measures of social functioning. Am J Psychiatry. 1992, 149: 1148-1156.
Article
CAS
PubMed
Google Scholar
Keller MB, Lavori PW, Friedman B, Nielsen E, Endicott J, McDonald-Scott P, Andreasen NC: The Longitudinal Interval Follow-up Evaluation. A comprehensive method for assessing outcome in prospective longitudinal studies. Arch Gen Psychiatry. 1987, 44: 540-548. 10.1001/archpsyc.1987.01800180050009.
Article
CAS
PubMed
Google Scholar
Leon AC, Solomon DA, Mueller TI, Turvey CL, Endicott J, Keller MB: The Range of Impaired Functioning Tool (LIFE-RIFT): a brief measure of functional impairment. Psychol Med. 1999, 29: 869-878. 10.1017/S0033291799008570.
Article
CAS
PubMed
Google Scholar
Endicott J, Nee J, Harrison W, Blumenthal R: Quality of Life Enjoyment and Satisfaction Questionnaire: a new measure. Psychopharmacol Bull. 1993, 29: 321-326.
CAS
PubMed
Google Scholar
International conference on harmonisation: guidance on statistical principles for clinical trials (ICH-E9). 1997, {AU Query: Please provide the name and place of the publisher.}
Mallinckrodt C, Watkin J, Molenberghs G, Carroll R: Choice of the primary analysis in longitudinal clinical trials. Pharmaceut Statist. 2004, 3: 161-169. 10.1002/pst.124.
Article
Google Scholar
Gueorgieva R, Krystal JH: Move over ANOVA: progress in analyzing repeated-measures data and its reflection in papers published in the Archives of General Psychiatry. Arch Gen Psychiatry. 2004, 61: 310-317. 10.1001/archpsyc.61.3.310.
Article
Google Scholar
Berk M, Copolov DL, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Bush AI: N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial. Biol Psychiatry. 2008, 64: 468-475. 10.1016/j.biopsych.2008.04.022.
Article
CAS
PubMed
Google Scholar
Magalhaes PV, Dean OM, Bush AI, Copolov DL, Malhi GS, Kohlmann K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Berk M: N-acetyl cysteine add-on treatment for bipolar II disorder: a subgroup analysis of a randomized placebo-controlled trial. J Affect Disord. 2011, 129: 317-320. 10.1016/j.jad.2010.08.001.
Article
CAS
PubMed
Google Scholar
Lafleur DL, Pittenger C, Kelmendi B, Gardner T, Wasylink S, Malison RT, Sanacora G, Krystal JH, Coric V: N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder. Psychopharmacology (Berl). 2006, 184: 254-256. 10.1007/s00213-005-0246-6.
Article
CAS
Google Scholar
Grant JE, Kim SW, Odlaug BL: N-Acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol Psychiatry. 2007, 62: 652-657. 10.1016/j.biopsych.2006.11.021.
Article
CAS
PubMed
Google Scholar
Lavoie S, Murray MM, Deppen P, Knyazeva MG, Berk M, Boulat O, Bovet P, Bush AI, Conus P, Copolov D, Fornari E, Meuli R, Solida A, Vianin P, Cuénod M, Buclin T, Do KQ: Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients. Neuropsychopharmacology. 2008, 33: 2187-2199. 10.1038/sj.npp.1301624.
Article
CAS
PubMed
Google Scholar
Qian HR, Yang Y: Neuron differentiation and neuritogenesis stimulated by N-acetylcysteine (NAC). Acta Pharmacol Sin. 2009, 30: 907-912. 10.1038/aps.2009.72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dodd S, Dean O, Copolov DL, Malhi GS, Berk M: N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility. Expert Opin Biol Ther. 2008, 8: 1955-1962. 10.1517/14728220802517901.
Article
CAS
PubMed
Google Scholar
Ferreira FR, Biojone C, Joca SR, Guimaraes FS: Antidepressant-like effects of N-acetyl-L-cysteine in rats. Behav Pharmacol. 2008, 19: 747-750. 10.1097/FBP.0b013e3283123c98.
Article
CAS
PubMed
Google Scholar
Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E, Butterfield DA, Morley JE: The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. 2003, 84: 1173-1183. 10.1046/j.1471-4159.2003.01580.x.
Article
CAS
PubMed
Google Scholar
Xiong Y, Peterson PL, Lee CP: Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats. J Neurotrauma. 1999, 16: 1067-1082. 10.1089/neu.1999.16.1067.
Article
CAS
PubMed
Google Scholar
Kato T, Kapczinski F, Berk M: Mitochondrial dysfunction and oxidative stress. Bipolar Disorder: Clinical and Neurobiological Foundations. Edited by: Yatham LN, Maj M. 2010, John Wiley & Sons Ltd, London, UK, 244-254.
Chapter
Google Scholar
Weisler RH, Nolen WA, Neijber A, Hellqvist A, Paulsson B: Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study). J Clin Psychiatry. 2011, 72: 1452-1464. 10.4088/JCP.11m06878.
Article
PubMed
Google Scholar