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933 result(s) for 'alcohol' within BMC Medicine

Page 15 of 19

  1. The 2018/2023 ESC/ESH Guidelines underlined a gap how baseline cardiovascular disease (CVD) risk predicted blood pressure (BP) lowering benefits. Further, 2017 ACC/AHA Guideline and 2021 WHO Guideline recommen...

    Authors: Guozhe Sun, Chang Wang, Ning Ye, Chuning Shi, Nanxiang Ouyang, Lixia Qiao, Guangxiao Li, Linlin Zhang, Yao Yu, Zhi Li, Ying Zhou, Zihan Chen, Shu Zhang, Pengyu Zhang, Danxi Geng, Wei Miao…
    Citation: BMC Medicine 2024 22:258
    Content type: Research article Published on:

  2. Nudging is increasingly used to promote healthy food choices in supermarkets. Ordering groceries online is gaining in popularity and nudging seems efficacious there as well, but is never comprehensively tested...

    Authors: Josine M. Stuber, Jeroen Lakerveld, Loes W. Kievitsbosch, Joreintje D. Mackenbach and Joline W. J. Beulens
    Citation: BMC Medicine 2022 20:10
    Content type: Research article Published on:

  4. There is growing evidence that substituting animal-based with plant-based foods is associated with a lower risk of cardiovascular diseases (CVD), type 2 diabetes (T2D), and all-cause mortality. Our aim was to ...

    Authors: Manuela Neuenschwander, Julia Stadelmaier, Julian Eble, Kathrin Grummich, Edyta Szczerba, Eva Kiesswetter, Sabrina Schlesinger and Lukas Schwingshackl
    Citation: BMC Medicine 2023 21:404
    Content type: Research article Published on:

    The Comment to this article has been published in BMC Global and Public Health 2024 2:3

  5. Global health is a varied field that comprises research, evaluation and policy that, by its definition, also occurs in disparate locations across the world. This forum article is introduced by our guest editor...

    Authors: Gretchen L Birbeck, Charles S Wiysonge, Edward J Mills, Julio J Frenk, Xiao-Nong Zhou and Prabhat Jha
    Citation: BMC Medicine 2013 11:223
    Content type: Forum Published on:

  6. Mitochondrial aldehyde dehydrogenase (ALDH2) displays some promise in the protection against cardiovascular diseases although its role in diabetes has not been elucidated.

    Authors: Yingmei Zhang, Sara A Babcock, Nan Hu, Jacalyn R Maris, Haichang Wang and Jun Ren
    Citation: BMC Medicine 2012 10:40
    Content type: Research article Published on:

  7. Clinical practice guidelines recommend sodium-glucose co-transporter 2 inhibitors (SGLT2is) to mitigate adverse kidney and cardiovascular outcomes in patients with type 2 diabetes (T2D), including patients wit...

    Authors: Csaba Kovesdy, Niklas Schmedt, Kerstin Folkerts, Kevin Bowrin, Hanaya Raad, Michael Batech and Linda Fried
    Citation: BMC Medicine 2022 20:2
    Content type: Research article Published on:

  8. The prevalence of combined heart failure (HF) and atrial fibrillation (AF) is rising, and these patients suffer from high rates of mortality. This study aims to provide robust data on factors associated with d...

    Authors: Otilia Èšica, Ovidiu Èšica, Karina V. Bunting, Joseph deBono, Georgios V. Gkoutos, Mircea I. Popescu and Dipak Kotecha
    Citation: BMC Medicine 2022 20:331
    Content type: Research article Published on:

  9. Plant-based diets rich in fruit and vegetables can prevent development of several chronic age-related diseases. However, the mechanisms behind this protective effect are not elucidated. We have tested the hypo...

    Authors: Siv K Bøhn, Mari C Myhrstad, Magne Thoresen, Marit Holden, Anette Karlsen, Siv Haugen Tunheim, Iris Erlund, Mette Svendsen, Ingebjørg Seljeflot, Jan Ø Moskaug, Asim K Duttaroy, Petter Laake, Harald Arnesen, Serena Tonstad, Andrew Collins, Christan A Drevon…
    Citation: BMC Medicine 2010 8:54
    Content type: Research article Published on:

  10. Lower limb injuries in sport are increasingly prevalent and responsible for large economic as well as personal burdens. In this review we seek to determine which easily implemented functional neuromuscular war...

    Authors: Katherine Herman, Christian Barton, Peter Malliaras and Dylan Morrissey
    Citation: BMC Medicine 2012 10:75
    Content type: Research article Published on:

  11. Prenatal maternal tobacco smoking is a predictor of child attention-deficit/hyperactivity disorder (ADHD) and is associated with offspring telomere length (TL). In this study, we examine the relationship betwe...

    Authors: Meghan P. Howell, Christopher W. Jones, Cade A. Herman, Celia V. Mayne, Camilo Fernandez, Katherine P. Theall, Kyle C. Esteves and Stacy S. Drury
    Citation: BMC Medicine 2022 20:153
    Content type: Research article Published on:

  12. Stillbirth rates have changed little over the last decade, and a high proportion of cases are unexplained. This meta-analysis examined whether there are inequalities in stillbirth risks according to sex.

    Authors: Debapriya Mondal, Tamara S Galloway, Trevor C Bailey and Fiona Mathews
    Citation: BMC Medicine 2014 12:220
    Content type: Research article Published on:

  13. To evaluate the neurological alterations induced by Omicron infection, to compare brain changes in chronic insomnia with those in exacerbated chronic insomnia in Omicron patients, and to examine individuals wi...

    Authors: Yanyao Du, Cong Li, Wei Zhao, Jinyue Li, Linlin Zhao, Huili Guo, Yingjia Jiang, Weiyin Vivian Liu, Song Zeng, Huiting Zhang, Hu Guo, Xuan Ouyang and Jun Liu
    Citation: BMC Medicine 2024 22:271
    Content type: Research Published on:

  14. Long-term opioid use is associated with dependency, addiction, and serious adverse events. Although a framework to reduce inappropriate opioid prescribing exists, there is no consensus on prescribing indicator...

    Authors: Neetu Bansal, Stephen M. Campbell, Chiu-Yi Lin, Darren M. Ashcroft and Li-Chia Chen
    Citation: BMC Medicine 2024 22:5
    Content type: Research article Published on:

  15. GT90001 (also known as PF-03446962) is an anti-ALK-1 monoclonal antibody and has shown activity in hepatocellular carcinoma (HCC). This phase 1b/2 study was designed to determine the recommended phase 2 dose (...

    Authors: Chiun Hsu, Yi-Fang Chang, Chia-Jui Yen, Yu-Wei Xu, Min Dong and You-Zhi Tong
    Citation: BMC Medicine 2023 21:395
    Content type: Research article Published on:

  16. Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading causes of cancer death. The incidence, pathological features, and clinical outcomes in breast cancer differ by geographic...

    Authors: Kelly A. Hirko, Gabrielle Rocque, Erica Reasor, Ammanuel Taye, Alex Daly, Ramsey I. Cutress, Ellen R. Copson, Dae-Won Lee, Kyung-Hun Lee, Seock-Ah Im and Yeon Hee Park
    Citation: BMC Medicine 2022 20:72
    Content type: Forum Published on:

  18. The associations of maternal cigarette smoking with congenital anomalies in offspring have been inconsistent. This study aimed to clarify the associations of the timing and intensity of maternal cigarette smok...

    Authors: Lili Yang, Huan Wang, Liu Yang, Min Zhao, Yajun Guo, Pascal Bovet and Bo Xi
    Citation: BMC Medicine 2022 20:4
    Content type: Research article Published on:

  19. Frailty has been identified as a risk factor for cognitive impairment and dementia. However, it is not known whether familial factors, such as genetics and shared environmental factors, underlie this associati...

    Authors: Ge Bai, Yunzhang Wang, Ralf Kuja-Halkola, Xia Li, Yasutake Tomata, Ida K. Karlsson, Nancy L. Pedersen, Sara Hägg and Juulia Jylhävä
    Citation: BMC Medicine 2021 19:248
    Content type: Research article Published on:

  20. Studies conducted during the early stages of the pandemic documented mixed changes in smoking behaviour: more smokers quitting successfully but little change in prevalence. This study aimed to examine whether ...

    Authors: Sarah E. Jackson, Harry Tattan-Birch, Lion Shahab, Emma Beard and Jamie Brown
    Citation: BMC Medicine 2023 21:474
    Content type: Research article Published on:

  22. The clustering of metabolic and cardiovascular risk factors is known as metabolic syndrome (MetS). The risk of having MetS is strongly associated with increased adiposity and can be further modified by smoking...

    Authors: Sandra N Slagter, Jana V van Vliet-Ostaptchouk, Judith M Vonk, H Marike Boezen, Robin PF Dullaart, Anneke C Muller Kobold, Edith J Feskens, André P van Beek, Melanie M van derKlauw and Bruce HR Wolffenbuttel
    Citation: BMC Medicine 2013 11:195
    Content type: Research article Published on:

  24. Dysbiosis of the gut microbiome is frequent in the intensive care unit (ICU), potentially leading to a heightened risk of nosocomial infections. Enhancing the gut microbiome has been proposed as a strategic ap...

    Authors: Vinod K. Gupta, Sanu Rajendraprasad, Mahmut Ozkan, Dhanya Ramachandran, Sumera Ahmad, Johan S. Bakken, Krzysztof Laudanski, Ognjen Gajic, Brent Bauer, Simon Zec, David W. Freeman, Sahil Khanna, Aditya Shah, Joseph H. Skalski, Jaeyun Sung and Lioudmila V. Karnatovskaia
    Citation: BMC Medicine 2024 22:80
    Content type: Research article Published on:

  25. Malaria is associated with Burkitt lymphoma among children in Sub-Saharan Africa. No longitudinal studies have assessed the long-term risk of other lymphoma or cancer overall. Here, we investigated the risk of...

    Authors: Katja Wyss, Fredrik Granath, Andreas Wångdahl, Therese Djärv, Michael Fored, Pontus Naucler and Anna Färnert
    Citation: BMC Medicine 2020 18:296
    Content type: Research article Published on:

  26. Thoracic aortic dissection (TAD) is a life-threatening disease caused by an intimal tear in the aorta. The histological characteristics differ significantly between the tear area (TA) and the distant area. Pre...

    Authors: Yixuan Sheng, Liying Wu, Yuan Chang, Wendao Liu, Menghao Tao, Xiao Chen, Xiong Zhang, Bin Li, Ningning Zhang, Dongting Ye, Chunxi Zhang, Daliang Zhu, Haisen Zhao, Aijun Chen, Haisheng Chen and Jiangping Song
    Citation: BMC Medicine 2023 21:396
    Content type: Research article Published on:

  27. Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technologi...

    Authors: Daniela Elleri, David B Dunger and Roman Hovorka
    Citation: BMC Medicine 2011 9:120
    Content type: Review Published on:

  28. Plasma cell-free DNA (cfDNA) methylation has shown promising results in the early detection of multiple cancers recently. Here, we conducted a study to investigate the performance of cfDNA methylation in the e...

    Authors: Guibin Qiao, Weitao Zhuang, Bo Dong, Chengcheng Li, Jiayue Xu, Guoqiang Wang, Liang Xie, Zihao Zhou, Dan Tian, Gang Chen, Jiming Tang, Haiyu Zhou, Dongkun Zhang, Ruiqing Shi, Rixin Chen, Weiqi Nian…
    Citation: BMC Medicine 2021 19:243
    Content type: Research article Published on:

  30. Dexmedetomidine is a sedative agent that may have the potential to reduce the risk of post-intensive care syndrome (PICS). This study aimed to establish whether prophylactic nocturnal dexmedetomidine safely re...

    Authors: Chun-hui Dong, Chao-nan Gao, Xiao-hua An, Na Li, Le Yang, De-cai Li and Qi Tan
    Citation: BMC Medicine 2021 19:306
    Content type: Research article Published on:

  31. Malnutrition is associated with poor overall survival (OS) in breast cancer patients; however, the most predictive nutritional indicators for the prognosis of patients with breast cancer are not well-establish...

    Authors: Jinyu Shi, Tong Liu, Yizhong Ge, Chenan Liu, Qi Zhang, Hailun Xie, Guotian Ruan, Shiqi Lin, Xin Zheng, Yue Chen, Heyang Zhang, Mengmeng Song, Xiaowei Zhang, Chunlei Hu, Xiangrui Li, Ming Yang…
    Citation: BMC Medicine 2023 21:512
    Content type: Research article Published on:

  32. Residents of the Republic of Serbia faced civil war and a NATO-led bombing campaign in 1999. We sought to assess the burden of metal health dysfunction among emergency department (ED) patients presenting for c...

    Authors: Brett D Nelson, William G Fernandez, Sandro Galea, Sarah Sisco, Kerry Dierberg, Gordana Subaric Gorgieva, Arijit K Nandi, Jennifer Ahern, Mihajlo Mitrović, Michael VanRooyen and David Vlahov
    Citation: BMC Medicine 2004 2:22
    Content type: Research article Published on:

  33. AD16 is a Class 1.1 new drug candidate for Alzheimer’s disease (AD), which has demonstrated potential benefits in AD by reducing neuroinflammation in preclinical studies. Herein, the pharmacokinetics (PK), saf...

    Authors: Daizhuang Peng, Sumei Xu, Ting Zou, Yahui Wang, Wenjuan Ouyang, Yalan Zhang, Chengmei Dong, Dai Li, Jie Guo, Qiuying Shen, Xiaolei Hu, Wenzhi Zhou, Xiaomin Li and Qun Qin
    Citation: BMC Medicine 2023 21:459
    Content type: Research article Published on:

  34. Preterm birth affects almost 9–11% of newborns and is one of the leading causes of childhood neurodevelopmental disabilities; the underlying molecular networks are poorly defined. In neurons, retrotransposons ...

    Authors: Camilla Fontana, Federica Marasca, Livia Provitera, Sara Mancinelli, Nicola Pesenti, Shruti Sinha, Sofia Passera, Sergio Abrignani, Fabio Mosca, Simona Lodato, Beatrice Bodega and Monica Fumagalli
    Citation: BMC Medicine 2021 19:42
    Content type: Research article Published on:

  35. Currently, many patients suffering from dementia do not have a diagnosis when admitted to geriatric hospitals. This is the case despite an increased risk of complications affecting the length of stay and outco...

    Authors: Wolfgang Trapp, Susanne Röder, Andreas Heid, Pia Billman, Susanne Daiber and Göran Hajak
    Citation: BMC Medicine 2021 19:65
    Content type: Research article Published on:

  36. Long-term intake of a Western diet (WD), characterized by a high-fat content and sugary drinks, is hypothesized to contribute to the development of inflammatory bowel disease (IBD). Despite the identified clin...

    Authors: Woo-Jeong Shon, Jae Won Song, Seung Hoon Oh, Keon-Hee Lee, Hobin Seong, Hyun Ju You, Je Kyung Seong and Dong-Mi Shin
    Citation: BMC Medicine 2023 21:165
    Content type: Research article Published on:

  37. Both depression and breast cancer (BC) contribute to a substantial global burden of morbidity and mortality among women, and previous studies have observed a potential depression-BC link. We aimed to comprehen...

    Authors: Xueyao Wu, Wenqiang Zhang, Xunying Zhao, Li Zhang, Minghan Xu, Yu Hao, Jinyu Xiao, Ben Zhang, Jiayuan Li, Peter Kraft, Jordan W. Smoller and Xia Jiang
    Citation: BMC Medicine 2023 21:170
    Content type: Research article Published on:

    The Commentary to this article has been published in BMC Medicine 2023 21:203

  38. Alterations in sleep have been described in multiple health conditions and as a function of several medication effects. However, evidence generally stems from small univariate studies. Here, we apply a large-s...

    Authors: Péter Przemyslaw Ujma and Róbert Bódizs
    Citation: BMC Medicine 2024 22:134
    Content type: Research article Published on:

  39. Due to low numbers of active infections and persons presenting to health facilities for malaria treatment, case-based surveillance is inefficient for understanding the remaining disease burden in low malaria t...

    Authors: Alicia Jaramillo-Underwood, Camelia Herman, Samuel E. Jean, Doug Nace, E. Scott Elder, Keri Robinson, Alaine Knipes, Caitlin M. Worrell, LeAnne M. Fox, Luccene Desir, Carl Fayette, Alain Javel, Franck Monestime, Kimberly E. Mace, Venkatachalam Udhayakumar, Kimberly Y. Won…
    Citation: BMC Medicine 2024 22:31
    Content type: Research article Published on:

  40. Sex and gender are fundamental aspects of health and wellbeing. Yet many research studies fail to consider sex or gender differences, and even when they do this is often limited to merely cataloguing such diff...

    Authors: Sanne A. E. Peters and Mark Woodward
    Citation: BMC Medicine 2023 21:354
    Content type: Research article Published on:

  41. Current evidence relating birthweight and gestational age to cardiovascular risk is conflicting. Whether these factors have independent or interactive impacts on cardiovascular parameters during early childhoo...

    Authors: Bowen Du, Hualin Wang, Yujian Wu, Zhuoyan Li, Yiwei Niu, Qianchuo Wang, Lin Zhang, Sun Chen, Yurong Wu, Jihong Huang, Kun Sun and Jian Wang
    Citation: BMC Medicine 2023 21:103
    Content type: Research article Published on:

  42. Accurate and non-invasive diagnosis of pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP) can avoid unnecessary puncture and surgery. This study aimed to develop a deep learning radiomics (D...

    Authors: Tong Tong, Jionghui Gu, Dong Xu, Ling Song, Qiyu Zhao, Fang Cheng, Zhiqiang Yuan, Shuyuan Tian, Xin Yang, Jie Tian, Kun Wang and Tian’an Jiang
    Citation: BMC Medicine 2022 20:74
    Content type: Research article Published on:

  43. Cisplatin resistance is one of the main causes of treatment failure and death in head and neck squamous cell carcinoma (HNSCC). A more comprehensive understanding of the cisplatin resistance mechanism and the ...

    Authors: Tong Tong, Xing Qin, Yingying Jiang, Haiyan Guo, Xiaoning Wang, Yan Li, Fei Xie, Hao Lu, Peisong Zhai, Hailong Ma and Jianjun Zhang
    Citation: BMC Medicine 2022 20:231
    Content type: Research article Published on:

  44. Leukocyte telomere length (LTL) is suggested to be a biomarker of biological age and reported to be associated with metabolic diseases such as type 2 diabetes. Glucose metabolic traits including glucose and in...

    Authors: Kwun Kiu Wong, Feifei Cheng, Cadmon K. P. Lim, Claudia H. T. Tam, Greg Tutino, Lai Yuk Yuen, Chi Chiu Wang, Yong Hou, Michael H. M. Chan, Chung Shun Ho, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Boyd E. Metzger, William L. Lowe Jr., Wing Hung Tam…
    Citation: BMC Medicine 2022 20:490
    Content type: Research article Published on:

  45. Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unkn...

    Authors: Jodie M Fleming, Tyler C Miller, Mariam Quinones, Zhen Xiao, Xia Xu, Matthew J Meyer, Erika Ginsburg, Timothy D Veenstra and Barbara K Vonderhaar
    Citation: BMC Medicine 2010 8:27
    Content type: Research article Published on:

  46. Limited evidence demonstrated the potential relationship between dietary sugar intake and dementia. This association demands further clarification in a large-scale population.

    Authors: Sirui Zhang, Yi Xiao, Yangfan Cheng, Yuanzheng Ma, Jiyong Liu, Chunyu Li and Huifang Shang
    Citation: BMC Medicine 2024 22:298
    Content type: Research article Published on:

  47. Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when response to pharmacological modalities is considered inadequate and sym...

    Authors: Vasilios Karageorgiou, Francesco Casanova, Jessica O’Loughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden and Jessica Tyrrell
    Citation: BMC Medicine 2023 21:355
    Content type: Research article Published on:

  48. High-grade serous carcinoma (HGSC) is the most frequent and lethal type of ovarian cancer. It has been proposed that tubal secretory cells are the origin of ovarian HGSC in women with familial BRCA1/2 mutations. ...

    Authors: Xuexin Yu, Wanrun Lin, Alexandra Spirtos, Yan Wang, Hao Chen, Jianfeng Ye, Jessica Parker, Ci Ci Liu, Yiying Wang, Gabriella Quinn, Feng Zhou, Setsuko K. Chambers, Cheryl Lewis, Jayanthi Lea, Bo Li and Wenxin Zheng
    Citation: BMC Medicine 2022 20:283
    Content type: Research article Published on:

  49. The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Me...

    Authors: Charles B Nemeroff, Daniel Weinberger, Michael Rutter, Harriet L MacMillan, Richard A Bryant, Simon Wessely, Dan J Stein, Carmine M Pariante, Florian Seemüller, Michael Berk, Gin S Malhi, Martin Preisig, Martin Brüne and Paul Lysaker
    Citation: BMC Medicine 2013 11:202
    Content type: Forum Published on:

  50. In this study, a combination of recombinant adenoviral p53 (rAd-p53) gene therapy and intra-arterial delivery of chemotherapeutic agents for treatment of oral squamous cell carcinoma was evaluated.

    Authors: Yi Li, Long-Jiang Li, Li-Juan Wang, Zhuang Zhang, Ning Gao, Chen-Yuan Liang, Yuan-Ding Huang and Bo Han
    Citation: BMC Medicine 2014 12:16
    Content type: Research article Published on:
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