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919 result(s) for 'alcohol' within BMC Medicine

Page 15 of 19

  1. Prenatal maternal tobacco smoking is a predictor of child attention-deficit/hyperactivity disorder (ADHD) and is associated with offspring telomere length (TL). In this study, we examine the relationship betwe...

    Authors: Meghan P. Howell, Christopher W. Jones, Cade A. Herman, Celia V. Mayne, Camilo Fernandez, Katherine P. Theall, Kyle C. Esteves and Stacy S. Drury
    Citation: BMC Medicine 2022 20:153
  2. Stillbirth rates have changed little over the last decade, and a high proportion of cases are unexplained. This meta-analysis examined whether there are inequalities in stillbirth risks according to sex.

    Authors: Debapriya Mondal, Tamara S Galloway, Trevor C Bailey and Fiona Mathews
    Citation: BMC Medicine 2014 12:220
  3. Long-term opioid use is associated with dependency, addiction, and serious adverse events. Although a framework to reduce inappropriate opioid prescribing exists, there is no consensus on prescribing indicator...

    Authors: Neetu Bansal, Stephen M. Campbell, Chiu-Yi Lin, Darren M. Ashcroft and Li-Chia Chen
    Citation: BMC Medicine 2024 22:5
  4. GT90001 (also known as PF-03446962) is an anti-ALK-1 monoclonal antibody and has shown activity in hepatocellular carcinoma (HCC). This phase 1b/2 study was designed to determine the recommended phase 2 dose (...

    Authors: Chiun Hsu, Yi-Fang Chang, Chia-Jui Yen, Yu-Wei Xu, Min Dong and You-Zhi Tong
    Citation: BMC Medicine 2023 21:395
  5. Breast cancer is the most commonly diagnosed cancer worldwide and is one of the leading causes of cancer death. The incidence, pathological features, and clinical outcomes in breast cancer differ by geographic...

    Authors: Kelly A. Hirko, Gabrielle Rocque, Erica Reasor, Ammanuel Taye, Alex Daly, Ramsey I. Cutress, Ellen R. Copson, Dae-Won Lee, Kyung-Hun Lee, Seock-Ah Im and Yeon Hee Park
    Citation: BMC Medicine 2022 20:72
  6. The associations of maternal cigarette smoking with congenital anomalies in offspring have been inconsistent. This study aimed to clarify the associations of the timing and intensity of maternal cigarette smok...

    Authors: Lili Yang, Huan Wang, Liu Yang, Min Zhao, Yajun Guo, Pascal Bovet and Bo Xi
    Citation: BMC Medicine 2022 20:4
  7. Frailty has been identified as a risk factor for cognitive impairment and dementia. However, it is not known whether familial factors, such as genetics and shared environmental factors, underlie this associati...

    Authors: Ge Bai, Yunzhang Wang, Ralf Kuja-Halkola, Xia Li, Yasutake Tomata, Ida K. Karlsson, Nancy L. Pedersen, Sara Hägg and Juulia Jylhävä
    Citation: BMC Medicine 2021 19:248
  8. Studies conducted during the early stages of the pandemic documented mixed changes in smoking behaviour: more smokers quitting successfully but little change in prevalence. This study aimed to examine whether ...

    Authors: Sarah E. Jackson, Harry Tattan-Birch, Lion Shahab, Emma Beard and Jamie Brown
    Citation: BMC Medicine 2023 21:474
  9. The clustering of metabolic and cardiovascular risk factors is known as metabolic syndrome (MetS). The risk of having MetS is strongly associated with increased adiposity and can be further modified by smoking...

    Authors: Sandra N Slagter, Jana V van Vliet-Ostaptchouk, Judith M Vonk, H Marike Boezen, Robin PF Dullaart, Anneke C Muller Kobold, Edith J Feskens, André P van Beek, Melanie M van derKlauw and Bruce HR Wolffenbuttel
    Citation: BMC Medicine 2013 11:195
  10. Dysbiosis of the gut microbiome is frequent in the intensive care unit (ICU), potentially leading to a heightened risk of nosocomial infections. Enhancing the gut microbiome has been proposed as a strategic ap...

    Authors: Vinod K. Gupta, Sanu Rajendraprasad, Mahmut Ozkan, Dhanya Ramachandran, Sumera Ahmad, Johan S. Bakken, Krzysztof Laudanski, Ognjen Gajic, Brent Bauer, Simon Zec, David W. Freeman, Sahil Khanna, Aditya Shah, Joseph H. Skalski, Jaeyun Sung and Lioudmila V. Karnatovskaia
    Citation: BMC Medicine 2024 22:80
  11. Malaria is associated with Burkitt lymphoma among children in Sub-Saharan Africa. No longitudinal studies have assessed the long-term risk of other lymphoma or cancer overall. Here, we investigated the risk of...

    Authors: Katja Wyss, Fredrik Granath, Andreas Wångdahl, Therese Djärv, Michael Fored, Pontus Naucler and Anna Färnert
    Citation: BMC Medicine 2020 18:296
  12. Thoracic aortic dissection (TAD) is a life-threatening disease caused by an intimal tear in the aorta. The histological characteristics differ significantly between the tear area (TA) and the distant area. Pre...

    Authors: Yixuan Sheng, Liying Wu, Yuan Chang, Wendao Liu, Menghao Tao, Xiao Chen, Xiong Zhang, Bin Li, Ningning Zhang, Dongting Ye, Chunxi Zhang, Daliang Zhu, Haisen Zhao, Aijun Chen, Haisheng Chen and Jiangping Song
    Citation: BMC Medicine 2023 21:396
  13. Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technologi...

    Authors: Daniela Elleri, David B Dunger and Roman Hovorka
    Citation: BMC Medicine 2011 9:120
  14. Plasma cell-free DNA (cfDNA) methylation has shown promising results in the early detection of multiple cancers recently. Here, we conducted a study to investigate the performance of cfDNA methylation in the e...

    Authors: Guibin Qiao, Weitao Zhuang, Bo Dong, Chengcheng Li, Jiayue Xu, Guoqiang Wang, Liang Xie, Zihao Zhou, Dan Tian, Gang Chen, Jiming Tang, Haiyu Zhou, Dongkun Zhang, Ruiqing Shi, Rixin Chen, Weiqi Nian…
    Citation: BMC Medicine 2021 19:243
  15. Dexmedetomidine is a sedative agent that may have the potential to reduce the risk of post-intensive care syndrome (PICS). This study aimed to establish whether prophylactic nocturnal dexmedetomidine safely re...

    Authors: Chun-hui Dong, Chao-nan Gao, Xiao-hua An, Na Li, Le Yang, De-cai Li and Qi Tan
    Citation: BMC Medicine 2021 19:306
  16. Malnutrition is associated with poor overall survival (OS) in breast cancer patients; however, the most predictive nutritional indicators for the prognosis of patients with breast cancer are not well-establish...

    Authors: Jinyu Shi, Tong Liu, Yizhong Ge, Chenan Liu, Qi Zhang, Hailun Xie, Guotian Ruan, Shiqi Lin, Xin Zheng, Yue Chen, Heyang Zhang, Mengmeng Song, Xiaowei Zhang, Chunlei Hu, Xiangrui Li, Ming Yang…
    Citation: BMC Medicine 2023 21:512
  17. Residents of the Republic of Serbia faced civil war and a NATO-led bombing campaign in 1999. We sought to assess the burden of metal health dysfunction among emergency department (ED) patients presenting for c...

    Authors: Brett D Nelson, William G Fernandez, Sandro Galea, Sarah Sisco, Kerry Dierberg, Gordana Subaric Gorgieva, Arijit K Nandi, Jennifer Ahern, Mihajlo Mitrović, Michael VanRooyen and David Vlahov
    Citation: BMC Medicine 2004 2:22
  18. AD16 is a Class 1.1 new drug candidate for Alzheimer’s disease (AD), which has demonstrated potential benefits in AD by reducing neuroinflammation in preclinical studies. Herein, the pharmacokinetics (PK), saf...

    Authors: Daizhuang Peng, Sumei Xu, Ting Zou, Yahui Wang, Wenjuan Ouyang, Yalan Zhang, Chengmei Dong, Dai Li, Jie Guo, Qiuying Shen, Xiaolei Hu, Wenzhi Zhou, Xiaomin Li and Qun Qin
    Citation: BMC Medicine 2023 21:459
  19. Preterm birth affects almost 9–11% of newborns and is one of the leading causes of childhood neurodevelopmental disabilities; the underlying molecular networks are poorly defined. In neurons, retrotransposons ...

    Authors: Camilla Fontana, Federica Marasca, Livia Provitera, Sara Mancinelli, Nicola Pesenti, Shruti Sinha, Sofia Passera, Sergio Abrignani, Fabio Mosca, Simona Lodato, Beatrice Bodega and Monica Fumagalli
    Citation: BMC Medicine 2021 19:42
  20. Currently, many patients suffering from dementia do not have a diagnosis when admitted to geriatric hospitals. This is the case despite an increased risk of complications affecting the length of stay and outco...

    Authors: Wolfgang Trapp, Susanne Röder, Andreas Heid, Pia Billman, Susanne Daiber and Göran Hajak
    Citation: BMC Medicine 2021 19:65
  21. Long-term intake of a Western diet (WD), characterized by a high-fat content and sugary drinks, is hypothesized to contribute to the development of inflammatory bowel disease (IBD). Despite the identified clin...

    Authors: Woo-Jeong Shon, Jae Won Song, Seung Hoon Oh, Keon-Hee Lee, Hobin Seong, Hyun Ju You, Je Kyung Seong and Dong-Mi Shin
    Citation: BMC Medicine 2023 21:165
  22. Both depression and breast cancer (BC) contribute to a substantial global burden of morbidity and mortality among women, and previous studies have observed a potential depression-BC link. We aimed to comprehen...

    Authors: Xueyao Wu, Wenqiang Zhang, Xunying Zhao, Li Zhang, Minghan Xu, Yu Hao, Jinyu Xiao, Ben Zhang, Jiayuan Li, Peter Kraft, Jordan W. Smoller and Xia Jiang
    Citation: BMC Medicine 2023 21:170

    The Commentary to this article has been published in BMC Medicine 2023 21:203

  23. Alterations in sleep have been described in multiple health conditions and as a function of several medication effects. However, evidence generally stems from small univariate studies. Here, we apply a large-s...

    Authors: Péter Przemyslaw Ujma and Róbert Bódizs
    Citation: BMC Medicine 2024 22:134
  24. Due to low numbers of active infections and persons presenting to health facilities for malaria treatment, case-based surveillance is inefficient for understanding the remaining disease burden in low malaria t...

    Authors: Alicia Jaramillo-Underwood, Camelia Herman, Samuel E. Jean, Doug Nace, E. Scott Elder, Keri Robinson, Alaine Knipes, Caitlin M. Worrell, LeAnne M. Fox, Luccene Desir, Carl Fayette, Alain Javel, Franck Monestime, Kimberly E. Mace, Venkatachalam Udhayakumar, Kimberly Y. Won…
    Citation: BMC Medicine 2024 22:31
  25. Sex and gender are fundamental aspects of health and wellbeing. Yet many research studies fail to consider sex or gender differences, and even when they do this is often limited to merely cataloguing such diff...

    Authors: Sanne A. E. Peters and Mark Woodward
    Citation: BMC Medicine 2023 21:354
  26. Current evidence relating birthweight and gestational age to cardiovascular risk is conflicting. Whether these factors have independent or interactive impacts on cardiovascular parameters during early childhoo...

    Authors: Bowen Du, Hualin Wang, Yujian Wu, Zhuoyan Li, Yiwei Niu, Qianchuo Wang, Lin Zhang, Sun Chen, Yurong Wu, Jihong Huang, Kun Sun and Jian Wang
    Citation: BMC Medicine 2023 21:103
  27. Accurate and non-invasive diagnosis of pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP) can avoid unnecessary puncture and surgery. This study aimed to develop a deep learning radiomics (D...

    Authors: Tong Tong, Jionghui Gu, Dong Xu, Ling Song, Qiyu Zhao, Fang Cheng, Zhiqiang Yuan, Shuyuan Tian, Xin Yang, Jie Tian, Kun Wang and Tian’an Jiang
    Citation: BMC Medicine 2022 20:74
  28. Cisplatin resistance is one of the main causes of treatment failure and death in head and neck squamous cell carcinoma (HNSCC). A more comprehensive understanding of the cisplatin resistance mechanism and the ...

    Authors: Tong Tong, Xing Qin, Yingying Jiang, Haiyan Guo, Xiaoning Wang, Yan Li, Fei Xie, Hao Lu, Peisong Zhai, Hailong Ma and Jianjun Zhang
    Citation: BMC Medicine 2022 20:231
  29. Leukocyte telomere length (LTL) is suggested to be a biomarker of biological age and reported to be associated with metabolic diseases such as type 2 diabetes. Glucose metabolic traits including glucose and in...

    Authors: Kwun Kiu Wong, Feifei Cheng, Cadmon K. P. Lim, Claudia H. T. Tam, Greg Tutino, Lai Yuk Yuen, Chi Chiu Wang, Yong Hou, Michael H. M. Chan, Chung Shun Ho, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Boyd E. Metzger, William L. Lowe Jr., Wing Hung Tam…
    Citation: BMC Medicine 2022 20:490
  30. Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unkn...

    Authors: Jodie M Fleming, Tyler C Miller, Mariam Quinones, Zhen Xiao, Xia Xu, Matthew J Meyer, Erika Ginsburg, Timothy D Veenstra and Barbara K Vonderhaar
    Citation: BMC Medicine 2010 8:27
  31. Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when response to pharmacological modalities is considered inadequate and sym...

    Authors: Vasilios Karageorgiou, Francesco Casanova, Jessica O’Loughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden and Jessica Tyrrell
    Citation: BMC Medicine 2023 21:355
  32. High-grade serous carcinoma (HGSC) is the most frequent and lethal type of ovarian cancer. It has been proposed that tubal secretory cells are the origin of ovarian HGSC in women with familial BRCA1/2 mutations. ...

    Authors: Xuexin Yu, Wanrun Lin, Alexandra Spirtos, Yan Wang, Hao Chen, Jianfeng Ye, Jessica Parker, Ci Ci Liu, Yiying Wang, Gabriella Quinn, Feng Zhou, Setsuko K. Chambers, Cheryl Lewis, Jayanthi Lea, Bo Li and Wenxin Zheng
    Citation: BMC Medicine 2022 20:283
  33. The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Me...

    Authors: Charles B Nemeroff, Daniel Weinberger, Michael Rutter, Harriet L MacMillan, Richard A Bryant, Simon Wessely, Dan J Stein, Carmine M Pariante, Florian Seemüller, Michael Berk, Gin S Malhi, Martin Preisig, Martin Brüne and Paul Lysaker
    Citation: BMC Medicine 2013 11:202
  34. In this study, a combination of recombinant adenoviral p53 (rAd-p53) gene therapy and intra-arterial delivery of chemotherapeutic agents for treatment of oral squamous cell carcinoma was evaluated.

    Authors: Yi Li, Long-Jiang Li, Li-Juan Wang, Zhuang Zhang, Ning Gao, Chen-Yuan Liang, Yuan-Ding Huang and Bo Han
    Citation: BMC Medicine 2014 12:16
  35. It remains a challenge to predict the long-term response to antipsychotics in patients with schizophrenia who do not respond at an early stage. This study aimed to investigate the optimal predictive cut-off va...

    Authors: Yujun Long, Qiongqiong Wu, Ye Yang, Jingda Cai, Jingmei Xiao, Zhaoqian Liu, Yifeng Xu, Ying Chen, Manli Huang, Ruiguo Zhang, Xijia Xu, Jian Hu, Zhifen Liu, Fang Liu, Yingjun Zheng, Huaqing Meng…
    Citation: BMC Medicine 2023 21:263
  36. Both low‐carbohydrate (LC) and calorie-restricted (CR) diets have been shown to have metabolic benefits. However, the two regimens have yet to be thoroughly compared. We conducted a 12-week randomized trial to...

    Authors: Jia Sun, Yuting Ruan, Ningning Xu, Peili Wu, Nie Lin, Kun Yuan, Shengli An, Pei Kang, Shu Li, Qiya Huang, Yingzhang, Yuzhong Li, Jialin Su, Wenjun Ma, Bo Chen, Xiuwei Zhang…
    Citation: BMC Medicine 2023 21:192
  37. In both Europe and the US, resident physician work hour reduction has been a source of controversy within academic medicine. In 2008, the Institute of Medicine (IOM) recommended a reduction in resident physici...

    Authors: Alexander B Blum, Farbod Raiszadeh, Sandra Shea, David Mermin, Peter Lurie, Christopher P Landrigan and Charles A Czeisler
    Citation: BMC Medicine 2010 8:33
  38. Metabolic syndrome (METS) is an increasingly prevalent but poorly understood clinical condition characterized by insulin resistance, glucose intolerance, dyslipidemia, hypertension, and obesity. Increased oxid...

    Authors: Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus and Andreas Michalsen
    Citation: BMC Medicine 2012 10:54
  39. It has been postulated that non-steroidal anti-inflammatory drugs (NSAIDs) use leads to decreased prostate cancer (PCa) risk. In recent years, NSAIDs’ role in PCa development has been extensively studied; howe...

    Authors: Yanqiong Liu, Jun-Qiang Chen, Li Xie, Jian Wang, Taijie Li, Yu He, Yong Gao, Xue Qin and Shan Li
    Citation: BMC Medicine 2014 12:55
  40. Recent studies found associations between non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS), but the causal nature of this association is still uncertain.

    Authors: Dong Liu, Xue Gao, Xiong-Fei Pan, Tao Zhou, Cairong Zhu, Fei Li, Jian-Gao Fan, Giovanni Targher and Jian Zhao
    Citation: BMC Medicine 2023 21:62
  41. Preterm birth defined as delivery before 37 gestational weeks is a leading cause of neonatal and infant morbidity and mortality. The aim of this study is to summarize the evidence from meta-analyses of observa...

    Authors: Ioannis Mitrogiannis, Evangelos Evangelou, Athina Efthymiou, Theofilos Kanavos, Effrosyni Birbas, George Makrydimas and Stefania Papatheodorou
    Citation: BMC Medicine 2023 21:494
  42. Depression is the most common psychiatric disorder worldwide. The burden of disease for depression goes beyond functioning and quality of life and extends to somatic health. Depression has been shown to subseq...

    Authors: Brenda WJH Penninx, Yuri Milaneschi, Femke Lamers and Nicole Vogelzangs
    Citation: BMC Medicine 2013 11:129
  43. Whether a low-inflammatory diet relates to type 2 diabetes risk remains unclear. We examined the association between a low-inflammatory diet and risk of type 2 diabetes among normoglycemic and prediabetic part...

    Authors: Rongrong Yang, Jing Lin, Hongxi Yang, Michelle M. Dunk, Jiao Wang, Weili Xu and Yaogang Wang
    Citation: BMC Medicine 2023 21:483
  44. Cervical squamous cell carcinoma (SCC) is known to arise through increasingly higher-grade squamous intraepithelial lesions (SILs) or cervical intraepithelial neoplasias (CINs). This study aimed to describe se...

    Authors: Jianwei Zhang, Silu Meng, Xiaoyan Wang, Jun Wang, Xinran Fan, Haiying Sun, Ruoqi Ning, Bing Xiao, Xiangqin Li, Yao Jia, Dongli Kong, Ruqi Chen, Changyu Wang, Ding Ma and Shuang Li
    Citation: BMC Medicine 2022 20:437
  45. Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify l...

    Authors: Melissa D. Tharmalingam, Gabriele Matilionyte, William H. B. Wallace, Jan-Bernd Stukenborg, Kirsi Jahnukainen, Elizabeth Oliver, Anne Goriely, Sheila Lane, Jingtao Guo, Bradley Cairns, Anne Jorgensen, Caroline M. Allen, Federica Lopes, Richard A. Anderson, Norah Spears and Rod T. Mitchell
    Citation: BMC Medicine 2020 18:374
  46. Traditionally, studies investigating diet and health associations have focused on single nutrients. However, key nutrients co-exist in many common foods, and studies focusing solely on individual nutrients may...

    Authors: Min Gao, Susan A. Jebb, Paul Aveyard, Gina L. Ambrosini, Aurora Perez-Cornago, Jennifer Carter, Xinying Sun and Carmen Piernas
    Citation: BMC Medicine 2021 19:83

    The Commentary to this article has been published in BMC Medicine 2021 19:108