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889 result(s) for 'alcohol' within BMC Medicine

Page 15 of 18

  1. Due to low numbers of active infections and persons presenting to health facilities for malaria treatment, case-based surveillance is inefficient for understanding the remaining disease burden in low malaria t...

    Authors: Alicia Jaramillo-Underwood, Camelia Herman, Samuel E. Jean, Doug Nace, E. Scott Elder, Keri Robinson, Alaine Knipes, Caitlin M. Worrell, LeAnne M. Fox, Luccene Desir, Carl Fayette, Alain Javel, Franck Monestime, Kimberly E. Mace, Venkatachalam Udhayakumar, Kimberly Y. Won…
    Citation: BMC Medicine 2024 22:31
  2. Sex and gender are fundamental aspects of health and wellbeing. Yet many research studies fail to consider sex or gender differences, and even when they do this is often limited to merely cataloguing such diff...

    Authors: Sanne A. E. Peters and Mark Woodward
    Citation: BMC Medicine 2023 21:354
  3. Current evidence relating birthweight and gestational age to cardiovascular risk is conflicting. Whether these factors have independent or interactive impacts on cardiovascular parameters during early childhoo...

    Authors: Bowen Du, Hualin Wang, Yujian Wu, Zhuoyan Li, Yiwei Niu, Qianchuo Wang, Lin Zhang, Sun Chen, Yurong Wu, Jihong Huang, Kun Sun and Jian Wang
    Citation: BMC Medicine 2023 21:103
  4. Accurate and non-invasive diagnosis of pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP) can avoid unnecessary puncture and surgery. This study aimed to develop a deep learning radiomics (D...

    Authors: Tong Tong, Jionghui Gu, Dong Xu, Ling Song, Qiyu Zhao, Fang Cheng, Zhiqiang Yuan, Shuyuan Tian, Xin Yang, Jie Tian, Kun Wang and Tian’an Jiang
    Citation: BMC Medicine 2022 20:74
  5. Cisplatin resistance is one of the main causes of treatment failure and death in head and neck squamous cell carcinoma (HNSCC). A more comprehensive understanding of the cisplatin resistance mechanism and the ...

    Authors: Tong Tong, Xing Qin, Yingying Jiang, Haiyan Guo, Xiaoning Wang, Yan Li, Fei Xie, Hao Lu, Peisong Zhai, Hailong Ma and Jianjun Zhang
    Citation: BMC Medicine 2022 20:231
  6. Leukocyte telomere length (LTL) is suggested to be a biomarker of biological age and reported to be associated with metabolic diseases such as type 2 diabetes. Glucose metabolic traits including glucose and in...

    Authors: Kwun Kiu Wong, Feifei Cheng, Cadmon K. P. Lim, Claudia H. T. Tam, Greg Tutino, Lai Yuk Yuen, Chi Chiu Wang, Yong Hou, Michael H. M. Chan, Chung Shun Ho, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Boyd E. Metzger, William L. Lowe Jr., Wing Hung Tam…
    Citation: BMC Medicine 2022 20:490
  7. Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unkn...

    Authors: Jodie M Fleming, Tyler C Miller, Mariam Quinones, Zhen Xiao, Xia Xu, Matthew J Meyer, Erika Ginsburg, Timothy D Veenstra and Barbara K Vonderhaar
    Citation: BMC Medicine 2010 8:27
  8. Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when response to pharmacological modalities is considered inadequate and sym...

    Authors: Vasilios Karageorgiou, Francesco Casanova, Jessica O’Loughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden and Jessica Tyrrell
    Citation: BMC Medicine 2023 21:355
  9. High-grade serous carcinoma (HGSC) is the most frequent and lethal type of ovarian cancer. It has been proposed that tubal secretory cells are the origin of ovarian HGSC in women with familial BRCA1/2 mutations. ...

    Authors: Xuexin Yu, Wanrun Lin, Alexandra Spirtos, Yan Wang, Hao Chen, Jianfeng Ye, Jessica Parker, Ci Ci Liu, Yiying Wang, Gabriella Quinn, Feng Zhou, Setsuko K. Chambers, Cheryl Lewis, Jayanthi Lea, Bo Li and Wenxin Zheng
    Citation: BMC Medicine 2022 20:283
  10. The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Me...

    Authors: Charles B Nemeroff, Daniel Weinberger, Michael Rutter, Harriet L MacMillan, Richard A Bryant, Simon Wessely, Dan J Stein, Carmine M Pariante, Florian Seemüller, Michael Berk, Gin S Malhi, Martin Preisig, Martin Brüne and Paul Lysaker
    Citation: BMC Medicine 2013 11:202
  11. In this study, a combination of recombinant adenoviral p53 (rAd-p53) gene therapy and intra-arterial delivery of chemotherapeutic agents for treatment of oral squamous cell carcinoma was evaluated.

    Authors: Yi Li, Long-Jiang Li, Li-Juan Wang, Zhuang Zhang, Ning Gao, Chen-Yuan Liang, Yuan-Ding Huang and Bo Han
    Citation: BMC Medicine 2014 12:16
  12. It remains a challenge to predict the long-term response to antipsychotics in patients with schizophrenia who do not respond at an early stage. This study aimed to investigate the optimal predictive cut-off va...

    Authors: Yujun Long, Qiongqiong Wu, Ye Yang, Jingda Cai, Jingmei Xiao, Zhaoqian Liu, Yifeng Xu, Ying Chen, Manli Huang, Ruiguo Zhang, Xijia Xu, Jian Hu, Zhifen Liu, Fang Liu, Yingjun Zheng, Huaqing Meng…
    Citation: BMC Medicine 2023 21:263
  13. Both low‐carbohydrate (LC) and calorie-restricted (CR) diets have been shown to have metabolic benefits. However, the two regimens have yet to be thoroughly compared. We conducted a 12-week randomized trial to...

    Authors: Jia Sun, Yuting Ruan, Ningning Xu, Peili Wu, Nie Lin, Kun Yuan, Shengli An, Pei Kang, Shu Li, Qiya Huang, Yingzhang, Yuzhong Li, Jialin Su, Wenjun Ma, Bo Chen, Xiuwei Zhang…
    Citation: BMC Medicine 2023 21:192
  14. In both Europe and the US, resident physician work hour reduction has been a source of controversy within academic medicine. In 2008, the Institute of Medicine (IOM) recommended a reduction in resident physici...

    Authors: Alexander B Blum, Farbod Raiszadeh, Sandra Shea, David Mermin, Peter Lurie, Christopher P Landrigan and Charles A Czeisler
    Citation: BMC Medicine 2010 8:33
  15. Metabolic syndrome (METS) is an increasingly prevalent but poorly understood clinical condition characterized by insulin resistance, glucose intolerance, dyslipidemia, hypertension, and obesity. Increased oxid...

    Authors: Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus and Andreas Michalsen
    Citation: BMC Medicine 2012 10:54
  16. It has been postulated that non-steroidal anti-inflammatory drugs (NSAIDs) use leads to decreased prostate cancer (PCa) risk. In recent years, NSAIDs’ role in PCa development has been extensively studied; howe...

    Authors: Yanqiong Liu, Jun-Qiang Chen, Li Xie, Jian Wang, Taijie Li, Yu He, Yong Gao, Xue Qin and Shan Li
    Citation: BMC Medicine 2014 12:55
  17. Recent studies found associations between non-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS), but the causal nature of this association is still uncertain.

    Authors: Dong Liu, Xue Gao, Xiong-Fei Pan, Tao Zhou, Cairong Zhu, Fei Li, Jian-Gao Fan, Giovanni Targher and Jian Zhao
    Citation: BMC Medicine 2023 21:62
  18. Preterm birth defined as delivery before 37 gestational weeks is a leading cause of neonatal and infant morbidity and mortality. The aim of this study is to summarize the evidence from meta-analyses of observa...

    Authors: Ioannis Mitrogiannis, Evangelos Evangelou, Athina Efthymiou, Theofilos Kanavos, Effrosyni Birbas, George Makrydimas and Stefania Papatheodorou
    Citation: BMC Medicine 2023 21:494
  19. Depression is the most common psychiatric disorder worldwide. The burden of disease for depression goes beyond functioning and quality of life and extends to somatic health. Depression has been shown to subseq...

    Authors: Brenda WJH Penninx, Yuri Milaneschi, Femke Lamers and Nicole Vogelzangs
    Citation: BMC Medicine 2013 11:129
  20. Whether a low-inflammatory diet relates to type 2 diabetes risk remains unclear. We examined the association between a low-inflammatory diet and risk of type 2 diabetes among normoglycemic and prediabetic part...

    Authors: Rongrong Yang, Jing Lin, Hongxi Yang, Michelle M. Dunk, Jiao Wang, Weili Xu and Yaogang Wang
    Citation: BMC Medicine 2023 21:483
  21. Cervical squamous cell carcinoma (SCC) is known to arise through increasingly higher-grade squamous intraepithelial lesions (SILs) or cervical intraepithelial neoplasias (CINs). This study aimed to describe se...

    Authors: Jianwei Zhang, Silu Meng, Xiaoyan Wang, Jun Wang, Xinran Fan, Haiying Sun, Ruoqi Ning, Bing Xiao, Xiangqin Li, Yao Jia, Dongli Kong, Ruqi Chen, Changyu Wang, Ding Ma and Shuang Li
    Citation: BMC Medicine 2022 20:437
  22. Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify l...

    Authors: Melissa D. Tharmalingam, Gabriele Matilionyte, William H. B. Wallace, Jan-Bernd Stukenborg, Kirsi Jahnukainen, Elizabeth Oliver, Anne Goriely, Sheila Lane, Jingtao Guo, Bradley Cairns, Anne Jorgensen, Caroline M. Allen, Federica Lopes, Richard A. Anderson, Norah Spears and Rod T. Mitchell
    Citation: BMC Medicine 2020 18:374
  23. Traditionally, studies investigating diet and health associations have focused on single nutrients. However, key nutrients co-exist in many common foods, and studies focusing solely on individual nutrients may...

    Authors: Min Gao, Susan A. Jebb, Paul Aveyard, Gina L. Ambrosini, Aurora Perez-Cornago, Jennifer Carter, Xinying Sun and Carmen Piernas
    Citation: BMC Medicine 2021 19:83

    The Commentary to this article has been published in BMC Medicine 2021 19:108

  24. During the extremely challenging 4,487 km ultramarathon TransEurope-FootRace 2009, runners showed considerable reduction of body weight. The effects of this endurance run on brain volume changes but also possi...

    Authors: Wolfgang Freund, Sonja Faust, Frank Birklein, Christian Gaser, Arthur P Wunderlich, Marguerite Müller, Christian Billich, Markus S Juchems, Bernd L Schmitz, Georg Grön and Uwe H Schütz
    Citation: BMC Medicine 2012 10:170
  25. Onchocerciasis is a leading cause of blindness worldwide, hence elimination of the infection is an important health priority. Community-based treatment programs with ivermectin form the basis of control progra...

    Authors: Juan Carlos Vieira, Philip J Cooper, Raquel Lovato, Tamara Mancero, Jorge Rivera, Roberto Proaño, Andrea A López, Ronald H Guderian and José Rumbea Guzmán
    Citation: BMC Medicine 2007 5:9
  26. Castration-resistant prostate cancer often metastasizes to the bone, and such bone metastases eventually become resistant to available therapies, leading to the death of patients. Enriched in the bone, TGF-β p...

    Authors: Qingqing Huang, Mingcheng Liu, Duo Zhang, Bing-Biao Lin, Xing Fu, Zhiqian Zhang, Baotong Zhang and Jin-Tang Dong
    Citation: BMC Medicine 2023 21:68
  27. The validation of biomarkers has become a key goal of translational biomedical research. The purpose of this article is to discuss the role of biomarkers in the management of acute lung injury (ALI) and relate...

    Authors: Alastair G Proudfoot, Matthew Hind and Mark JD Griffiths
    Citation: BMC Medicine 2011 9:132
  28. Mental health conditions represent one of the major groups of non-transmissible diseases. Physical activity (PA) and sedentary time (ST) have been shown to affect mental health outcomes in opposite directions....

    Authors: Francesco Casanova, Jessica O’Loughlin, Vasilis Karageorgiou, Robin N. Beaumont, Jack Bowden, Andrew R. Wood and Jessica Tyrrell
    Citation: BMC Medicine 2023 21:501
  29. Cholera mainly affects developing countries where safe water supply and sanitation infrastructure are often rudimentary. Sub-Saharan Africa is a cholera hotspot. Effective cholera control requires not only a p...

    Authors: Christian Schaetti, Neisha Sundaram, Sonja Merten, Said M Ali, Erick O Nyambedha, Bruno Lapika, Claire-Lise Chaignat, Raymond Hutubessy and Mitchell G Weiss
    Citation: BMC Medicine 2013 11:206
  30. Coffee is the most widely consumed psychostimulant worldwide. Emerging evidence indicates that coffee consumption habit significantly reduces the risk of developing Parkinson’s disease (PD). However, the effec...

    Authors: Chao Wang, Cheng Zhou, Tao Guo, Yeerfan Jiaerken, Siyu Yang, Xiaopei Xu, Ling Hu, Peiyu Huang, Xiaojun Xu and Minming Zhang
    Citation: BMC Medicine 2023 21:272
  31. Preterm birth (PTB) is a leading cause of child morbidity and mortality. Evidence suggests an increased risk with both maternal underweight and obesity, with some studies suggesting underweight might be a grea...

    Authors: R. P. Cornish, M. C. Magnus, S. K. Urhoj, G. Santorelli, L. G. Smithers, D. Odd, A. Fraser, S. E. Håberg, A. M. Nybo Andersen, K. Birnie, J. W. Lynch, K. Tilling and D. A. Lawlor
    Citation: BMC Medicine 2024 22:10
  32. Numerous studies over the past four decades have revealed that breast cancer screening (BCS) significantly reduces breast cancer (BC) mortality. However, in BRICS-plus countries, the association between BCS an...

    Authors: Sumaira Mubarik, Saima Shakil Malik, Zhang Yanran, Eelko Hak, Nawsherwan, Fang Wang and Chuanhua Yu
    Citation: BMC Medicine 2023 21:299
  33. The identification of pathogenic mutations in Alzheimer’s disease (AD) causal genes led to a better understanding of the pathobiology of AD. Familial Alzheimer’s disease (FAD) is known to be associated with mu...

    Authors: Wenwen Li, Yana Pang, Yan Wang, Fan Mei, Mengmeng Guo, Yiping Wei, Xinyue Li, Wei Qin, Wei Wang, Longfei Jia and Jianping Jia
    Citation: BMC Medicine 2023 21:223
  34. There is little evidence on whether PM2.5 and ground surface ozone have consistent effects on increased individual medical costs, and there is a lack of evidence on causality in developing countries.

    Authors: Ke Ju, Liyong Lu, Jingguo Yang, Ting Chen, Tianjiao Lan, Zhongxin Duan, Zongyou Xu, En Zhang, Wen Wang and Jay Pan
    Citation: BMC Medicine 2023 21:127
  35. In March 2020, the UK implemented the Coronavirus Job Retention Scheme (furlough) to minimise job losses. Our aim was to investigate associations between furlough and diet, physical activity, and sleep during ...

    Authors: Bożena Wielgoszewska, Jane Maddock, Michael J. Green, Giorgio Di Gessa, Sam Parsons, Gareth J. Griffith, Jazz Croft, Anna J. Stevenson, Charlotte Booth, Richard J. Silverwood, David Bann, Praveetha Patalay, Alun D. Hughes, Nishi Chaturvedi, Laura D. Howe, Emla Fitzsimons…
    Citation: BMC Medicine 2022 20:147

    The Correction to this article has been published in BMC Medicine 2022 20:285

  36. As malaria transmission declines, sensitive diagnostics are needed to evaluate interventions and monitor transmission. Serological assays measuring malaria antibody responses offer a cost-effective detection m...

    Authors: Lindsey Wu, Julia Mwesigwa, Muna Affara, Mamadou Bah, Simon Correa, Tom Hall, Susheel K. Singh, James G. Beeson, Kevin K. A. Tetteh, Immo Kleinschmidt, Umberto D’Alessandro and Chris Drakeley
    Citation: BMC Medicine 2020 18:304
  37. Disparities in health by adult income are well documented, but we know less about the childhood origins of health inequalities, and it remains unclear how the shape of the gradient varies across health conditi...

    Authors: Miriam Evensen, Søren Toksvig Klitkou, Mette C. Tollånes, Simon Øverland, Torkild Hovde Lyngstad, Stein Emil Vollset and Jonas Minet Kinge
    Citation: BMC Medicine 2021 19:152
  38. Although electroconvulsive therapy (ECT) is an effective treatment for depression, ECT cognitive impairment remains a major concern. The neurobiological underpinnings and mechanisms underlying ECT antidepressa...

    Authors: Shile Qi, Vince D. Calhoun, Daoqiang Zhang, Jeremy Miller, Zhi-De Deng, Katherine L. Narr, Yvette Sheline, Shawn M. McClintock, Rongtao Jiang, Xiao Yang, Joel Upston, Tom Jones, Jing Sui and Christopher C. Abbott
    Citation: BMC Medicine 2022 20:477

    The Correction to this article has been published in BMC Medicine 2023 21:113

  39. Prostate cancer (PCa) is the most common malignancy diagnosed in men. Immune checkpoint blockade (ICB) alone showed disappointing results in PCa. It is partly due to the formation of immunosuppressive tumor mi...

    Authors: Zude Chen, Xiaoshuang Yang, Zugen Chen, Minzhao Li, Wei Wang, Riwei Yang, Zuomin Wang, Yuxiang Ma, Yulong Xu, Shan Ao, Leqi Liang, Chao Cai, Changning Wang, Tuo Deng, Di Gu, Hongqing Zhou…
    Citation: BMC Medicine 2023 21:402
  40. Although immune checkpoint inhibitors (ICIs) have influenced the treatment paradigm for multiple solid tumors, increasing evidence suggests that primary and adaptive resistance may limit the long-term efficacy...

    Authors: Pei Zhang, Yang Du, Hua Bai, Zhijie Wang, Jianchun Duan, Xin Wang, Jia Zhong, Rui Wan, Jiachen Xu, Xiran He, Di Wang, Kailun Fei, Ruofei Yu, Jie Tian and Jie Wang
    Citation: BMC Medicine 2022 20:435
  41. Retinal structural abnormalities have been found to serve as biomarkers for cardiovascular disease (CVD). However, the association between retinal nerve fiber layer (RNFL) thickness and the incidence of CVD ev...

    Authors: Yanping Chen, Yixiong Yuan, Shiran Zhang, Shaopeng Yang, Junyao Zhang, Xiao Guo, Wenyong Huang, Zhuoting Zhu, Mingguang He and Wei Wang
    Citation: BMC Medicine 2023 21:24
  42. In childhood, attention deficit/hyperactivity disorder (ADHD) is characterized by age-inappropriate levels of inattentiveness/disorganization, hyperactivity/impulsiveness, or a combination thereof. Although th...

    Authors: Monica Shaw, Paul Hodgkins, Hervé Caci, Susan Young, Jennifer Kahle, Alisa G Woods and L Eugene Arnold
    Citation: BMC Medicine 2012 10:99
  43. Chronic fatigue syndrome, also known as ME (CFS/ME), is a condition characterised primarily by severe, disabling fatigue, of unknown origin, which has a poor prognosis and serious personal and economic consequ...

    Authors: AJ Wearden, L Riste, C Dowrick, C Chew-Graham, RP Bentall, RK Morriss, S Peters, G Dunn, G Richardson, K Lovell and P Powell
    Citation: BMC Medicine 2006 4:9
  44. Myocardial infarction (MI), stroke and diabetes share underlying risk factors and commonalities in clinical management. We examined if their combined impact on mortality is proportional, amplified or less than...

    Authors: Dexter Canoy, Jenny Tran, Mariagrazia Zottoli, Rema Ramakrishnan, Abdelaali Hassaine, Shishir Rao, Yikuan Li, Gholamreza Salimi-Khorshidi, Robyn Norton and Kazem Rahimi
    Citation: BMC Medicine 2021 19:258
  45. The FAST study identified claudin-18 (CLDN18.2) as a promising novel therapeutic target for gastric cancer (GC). However, the tumor immune microenvironment and clinicopathological features of CLDN18.2-positive...

    Authors: Keren Jia, Yang Chen, Yu Sun, Yajie Hu, Lei Jiao, Jie Ma, Jiajia Yuan, Changsong Qi, Yanyan Li, Jifang Gong, Jing Gao, Xiaotian Zhang, Jian Li, Cheng Zhang and Lin Shen
    Citation: BMC Medicine 2022 20:223

    The Correction to this article has been published in BMC Medicine 2023 21:369

  46. MitoQ is a mitochondria-targeted derivative of the antioxidant ubiquinone, with antioxidant and anti-apoptotic functions. Reactive oxygen species are involved in many inflammatory diseases including inflammato...

    Authors: Amarjargal Dashdorj, Jyothi KR, Sangbin Lim, Ara Jo, Minh Nam Nguyen, Joohun Ha, Kyung-Sik Yoon, Hyo Jong Kim, Jae-Hoon Park, Michael P Murphy and Sung Soo Kim
    Citation: BMC Medicine 2013 11:178
  47. Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metaboli...

    Authors: Marie Breeur, Pietro Ferrari, Laure Dossus, Mazda Jenab, Mattias Johansson, Sabina Rinaldi, Ruth C. Travis, Mathilde His, Tim J. Key, Julie A. Schmidt, Kim Overvad, Anne Tjønneland, Cecilie Kyrø, Joseph A. Rothwell, Nasser Laouali, Gianluca Severi…
    Citation: BMC Medicine 2022 20:351
  48. Gestational diabetes mellitus (GDM) is a metabolic disease that occurs in pregnant women and increases the risk for the development of diabetes. The relationship between GDM and meconium microbiota and metabol...

    Authors: Ting Chen, Yufeng Qin, Minjian Chen, Yuqing Zhang, Xu Wang, Tianyu Dong, Guanglin Chen, Xian Sun, Ting Lu, Richard Allen White III, Peng Ye, Hein M. Tun and Yankai Xia
    Citation: BMC Medicine 2021 19:120