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  1. Content type: Research article

    In the earlier randomized controlled Physical Activity during Cancer Treatment (PACT) study, we found beneficial effects of an 18-week supervised exercise program on fatigue in patients with newly diagnosed br...

    Authors: Lenja Witlox, Anouk E. Hiensch, Miranda J. Velthuis, Charlotte N. Steins Bisschop, Maartje Los, Frans L. G. Erdkamp, Haiko J. Bloemendal, Marlies Verhaar, Daan ten Bokkel Huinink, Elsken van der Wall, Petra H. M. Peeters and Anne M. May

    Citation: BMC Medicine 2018 16:86

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  2. Content type: Research article

    HIV increases the progression of latent tuberculosis (TB) infection to active disease and contributed to increased TB in the UK until 2004. We describe temporal trends in HIV infection amongst patients with TB...

    Authors: Joanne R. Winter, Helen R. Stagg, Colette J. Smith, Maeve K. Lalor, Jennifer A. Davidson, Alison E. Brown, James Brown, Dominik Zenner, Marc Lipman, Anton Pozniak, Ibrahim Abubakar and Valerie Delpech

    Citation: BMC Medicine 2018 16:85

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  3. Content type: Opinion

    Various Zika virus (ZIKV) vaccine candidates are currently in development. Nevertheless, unique challenges in clinical development and regulatory pathways may hinder the licensure of high-quality, safe, and ef...

    Authors: Annelies Wilder-Smith, Kirsten Vannice, Anna Durbin, Joachim Hombach, Stephen J. Thomas, Irani Thevarjan and Cameron P. Simmons

    Citation: BMC Medicine 2018 16:84

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  4. Content type: Minireview

    In real-world clinical practice, the acceptance of anticoagulation therapy in the management of portal vein thrombosis (PVT) in patients with cirrhosis is limited by the fear of an increased bleeding risk. Add...

    Authors: Xingshun Qi, Xiaozhong Guo, Eric M. Yoshida, Nahum Méndez-Sánchez, Valerio De Stefano, Frank Tacke, Andrea Mancuso, Yasuhiko Sugawara, Sien-Sing Yang, Rolf Teschke, Ankur Arora and Dominique-Charles Valla

    Citation: BMC Medicine 2018 16:83

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  5. Content type: Commentary

    The increasing number and global distribution of pathogens resistant to antimicrobial drugs is potentially one of the greatest threats to global health, leading to health crises arising from infections that we...

    Authors: Simon I. Hay, Puja C. Rao, Christiane Dolecek, Nicholas P. J. Day, Andy Stergachis, Alan D. Lopez and Christopher J. L. Murray

    Citation: BMC Medicine 2018 16:78

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  6. Content type: Research article

    Despite decades of experience with praziquantel treatment in school-aged children (SAC) and adults, we still face considerable knowledge gaps relevant to the successful treatment of preschool-aged children (PS...

    Authors: Jean T. Coulibaly, Gordana Panic, Richard B. Yapi, Jana Kovač, Beatrice Barda, Yves K. N’Gbesso, Jan Hattendorf and Jennifer Keiser

    Citation: BMC Medicine 2018 16:81

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  7. Content type: Research article

    Innovative ways of delivering care are needed to improve outcomes for older people with multimorbidity. Health coaching involves ‘a regular series of phone calls between patient and health professional to prov...

    Authors: Maria Panagioti, David Reeves, Rachel Meacock, Beth Parkinson, Karina Lovell, Mark Hann, Kelly Howells, Amy Blakemore, Lisa Riste, Peter Coventry, Thomas Blakeman, Mark Sidaway and Peter Bower

    Citation: BMC Medicine 2018 16:80

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  8. Content type: Research article

    The CD4/CD8 ratio has been associated with the risk of AIDS and non-AIDS events. We describe trends in immunological parameters in people who underwent a switch to monotherapy or dual therapy, compared to a co...

    Authors: Cristina Mussini, Patrizia Lorenzini, Alessandro Cozzi-Lepri, Giulia Marchetti, Stefano Rusconi, Andrea Gori, Silvia Nozza, Miriam Lichtner, Andrea Antinori, Andrea Cossarizza and Antonella d’Arminio Monforte

    Citation: BMC Medicine 2018 16:79

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  9. Content type: Research article

    The relationship between long-term exposure to whole body or central obesity and cognitive function, as well as its potential determinants, remain controversial. In this study, we assessed (1) the potential im...

    Authors: Stefano Masi, Georgios Georgiopoulos, Tauseef Khan, William Johnson, Andrew Wong, Marietta Charakida, Peter Whincup, Alun D. Hughes, Marcus Richards, Rebecca Hardy and John Deanfield

    Citation: BMC Medicine 2018 16:75

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  10. Content type: Research article

    The appropriate limit to the amount of daily sedentary time (ST) required to minimize mortality is uncertain. This meta-analysis aimed to quantify the dose-response association between daily ST and all-cause m...

    Authors: Po-Wen Ku, Andrew Steptoe, Yung Liao, Ming-Chun Hsueh and Li-Jung Chen

    Citation: BMC Medicine 2018 16:74

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  11. Content type: Research article

    Discretionary screen time (time spent viewing a television or computer screen during leisure time) is an important contributor to total sedentary behaviour, which is associated with increased risk of mortality...

    Authors: Carlos A. Celis-Morales, Donald M. Lyall, Lewis Steell, Stuart R. Gray, Stamatina Iliodromiti, Jana Anderson, Daniel F. Mackay, Paul Welsh, Thomas Yates, Jill P. Pell, Naveed Sattar and Jason M. R. Gill

    Citation: BMC Medicine 2018 16:77

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  12. Content type: Research article

    Reliable measures of disease burden over time are necessary to evaluate the impact of interventions and assess sub-national trends in the distribution of infection. Three Malaria Indicator Surveys (MISs) have ...

    Authors: Su Yun Kang, Katherine E. Battle, Harry S. Gibson, Arsène Ratsimbasoa, Milijaona Randrianarivelojosia, Stéphanie Ramboarina, Peter A. Zimmerman, Daniel J. Weiss, Ewan Cameron, Peter W. Gething and Rosalind E. Howes

    Citation: BMC Medicine 2018 16:71

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  13. Content type: Research article

    Effective coverage requires that those in need can access skilled care supported by adequate resources. There are, however, few studies of effective coverage of facility-based neonatal care in low-income setti...

    Authors: Georgina A. V. Murphy, David Gathara, Jacintah Mwachiro, Nancy Abuya, Jalemba Aluvaala and Mike English

    Citation: BMC Medicine 2018 16:72

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  14. Content type: Research article

    Chest radiographs are used for diagnosis and severity assessment in tuberculosis (TB). The extent of disease as determined by smear grade and cavitation as a binary measure can predict 2-month smear results, b...

    Authors: S. E. Murthy, F. Chatterjee, A. Crook, R. Dawson, C. Mendel, M. E. Murphy, S. R. Murray, A. J. Nunn, P. P. J. Phillips, Kasha P. Singh, T. D. McHugh and S. H. Gillespie

    Citation: BMC Medicine 2018 16:73

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  15. Content type: Research article

    Previous studies on high-risk opioid use have only focused on patients diagnosed with an opioid disorder. This study evaluates the impact of various high-risk prescription opioid use groups on healthcare costs...

    Authors: Hsien-Yen Chang, Hadi Kharrazi, Dave Bodycombe, Jonathan P. Weiner and G. Caleb Alexander

    Citation: BMC Medicine 2018 16:69

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  16. Content type: Research article

    Countries with ongoing outbreaks of Zika virus have observed a notable rise in reported cases of Guillain–Barré syndrome (GBS), with mounting evidence of a causal link between Zika virus infection and the neur...

    Authors: Luis Mier-y-Teran-Romero, Mark J. Delorey, James J. Sejvar and Michael A. Johansson

    Citation: BMC Medicine 2018 16:67

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  17. Content type: Research article

    Failures and partial successes are common in technology-supported innovation programmes in health and social care. Complexity theory can help explain why. Phenomena may be simple (straightforward, predictable,...

    Authors: Trisha Greenhalgh, Joe Wherton, Chrysanthi Papoutsi, Jenni Lynch, Gemma Hughes, Christine A’Court, Sue Hinder, Rob Procter and Sara Shaw

    Citation: BMC Medicine 2018 16:66

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  18. Content type: Opinion

    After 7 years of increasing conflict and violence, the Syrian civil war now constitutes the largest displacement crisis in the world, with more than 6 million people who have been internally displaced. Among t...

    Authors: Rahma Aburas, Amina Najeeb, Laila Baageel and Tim K. Mackey

    Citation: BMC Medicine 2018 16:65

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  19. Content type: Research article

    The Daily Mile is a physical activity programme made popular by a school in Stirling, Scotland. It is promoted by the Scottish Government and is growing in popularity nationally and internationally. The aim is...

    Authors: Ross A. Chesham, Josephine N. Booth, Emma L. Sweeney, Gemma C. Ryde, Trish Gorely, Naomi E. Brooks and Colin N. Moran

    Citation: BMC Medicine 2018 16:64

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  20. Content type: Research article

    Many clinical trials conducted by academic organizations are not published, or are not published completely. Following the US Food and Drug Administration Amendments Act of 2007, “The Final Rule” (compliance d...

    Authors: Evan Mayo-Wilson, James Heyward, Anthony Keyes, Jesse Reynolds, Sarah White, Nidhi Atri, G. Caleb Alexander, Audrey Omar and Daniel E. Ford

    Citation: BMC Medicine 2018 16:60

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  21. Content type: Opinion

    Implementation science has a core aim – to get evidence into practice. Early in the evidence-based medicine movement, this task was construed in linear terms, wherein the knowledge pipeline moved from evidence...

    Authors: Jeffrey Braithwaite, Kate Churruca, Janet C. Long, Louise A. Ellis and Jessica Herkes

    Citation: BMC Medicine 2018 16:63

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  22. Content type: Research article

    Antibodies targeting Plasmodium falciparum sporozoites play a key role in human immunity to malaria. However, antibody mechanisms that neutralize sporozoites are poorly understood. This has been a major constrain...

    Authors: Liriye Kurtovic, Marije C. Behet, Gaoqian Feng, Linda Reiling, Kiprotich Chelimo, Arlene E. Dent, Ivo Mueller, James W. Kazura, Robert W. Sauerwein, Freya J. I. Fowkes and James G. Beeson

    Citation: BMC Medicine 2018 16:61

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Page 2 of 81