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  1. Patient and public involvement (PPI) in research envisages a relationship built throughout the lifespan of a research project between academics, clinicians and PPI colleagues in order to inform, plan, execute ...

    Authors: Tracy Jackson, Hilary Pinnock, Su May Liew, Elsie Horne, Elisabeth Ehrlich, Olivia Fulton, Allison Worth, Aziz Sheikh and Anna De Simoni

    Citation: BMC Medicine 2020 18:79

    Content type: Opinion

    Published on:

  2. Multimorbidity is associated with mortality and service use, with specific types of multimorbidity having differential effects. Additionally, multimorbidity is often negatively associated with participation in...

    Authors: Yajing Zhu, Duncan Edwards, Jonathan Mant, Rupert A. Payne and Steven Kiddle

    Citation: BMC Medicine 2020 18:78

    Content type: Research article

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  3. Chronic kidney disease with metabolic acidosis is common in older people, but the effectiveness of oral sodium bicarbonate therapy in this group is unclear. We tested whether oral sodium bicarbonate provides n...

    Authors:

    Citation: BMC Medicine 2020 18:91

    Content type: Research article

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  4. The past decades of research have seen an increase in statistical tools to explore the complex dynamics of mental health from patient data, yet the application of these tools in clinical practice remains uncom...

    Authors: Julian Burger, Date C. van der Veen, Donald J. Robinaugh, Rick Quax, Harriëtte Riese, Robert A. Schoevers and Sacha Epskamp

    Citation: BMC Medicine 2020 18:99

    Content type: Research article

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  5. Mental ill-health in health professionals, including doctors, is a global and growing concern. The existing literature on interventions that offer support, advice and/or treatment to sick doctors has not yet b...

    Authors: Daniele Carrieri, Karen Mattick, Mark Pearson, Chrysanthi Papoutsi, Simon Briscoe, Geoff Wong and Mark Jackson

    Citation: BMC Medicine 2020 18:76

    Content type: Research article

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  6. Preterm birth, small size for gestational age (SGA) and large size for gestational age (LGA) at birth are major risk factors for neonatal and long-term morbidity and mortality. It is unclear which periods of p...

    Authors: Jan S. Erkamp, Ellis Voerman, Eric A. P. Steegers, Annemarie G. M. G. J. Mulders, Irwin K. M. Reiss, Liesbeth Duijts, Vincent W. V. Jaddoe and Romy Gaillard

    Citation: BMC Medicine 2020 18:63

    Content type: Research article

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  7. Respiratory syncytial virus (RSV) frequently causes acute lower respiratory infection in children under 5, representing a high burden in Gavi-eligible countries (mostly low-income and lower-middle-income). Sin...

    Authors: Xiao Li, Lander Willem, Marina Antillon, Joke Bilcke, Mark Jit and Philippe Beutels

    Citation: BMC Medicine 2020 18:82

    Content type: Research article

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  8. Education is widely associated with better physical and mental health, but isolating its causal effect is difficult because education is linked with many socioeconomic advantages. One way to isolate education’...

    Authors: Jessica Butler, Corri Black, Peter Craig, Chris Dibben, Ruth Dundas, Michelle Hilton Boon, Marjorie Johnston and Frank Popham

    Citation: BMC Medicine 2020 18:77

    Content type: Registered report

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  9. Infective endocarditis is an uncommon but serious infection, where evidence for giving antibiotic prophylaxis before invasive dental procedures is inconclusive. In England, antibiotic prophylaxis was offered r...

    Authors: T. Phuong Quan, Berit Muller-Pebody, Nicola Fawcett, Bernadette C. Young, Mehdi Minaji, Jonathan Sandoe, Susan Hopkins, Derrick Crook, Timothy Peto, Alan P. Johnson and A. Sarah Walker

    Citation: BMC Medicine 2020 18:84

    Content type: Research article

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  10. Transdiagnostic processes confer risk for multiple types of psychopathology and explain the co-occurrence of different disorders. For this reason, transdiagnostic processes provide ideal targets for early inte...

    Authors: Katie A. McLaughlin, Natalie L. Colich, Alexandra M. Rodman and David G. Weissman

    Citation: BMC Medicine 2020 18:96

    Content type: Opinion

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  11. Preterm delivery is an independent risk factor for maternal cardiovascular disease. Little is known about the association between preterm delivery and maternal renal function. This study aimed to examine wheth...

    Authors: Peter M. Barrett, Fergus P. McCarthy, Marie Evans, Marius Kublickas, Ivan J. Perry, Peter Stenvinkel, Karolina Kublickiene and Ali S. Khashan

    Citation: BMC Medicine 2020 18:66

    Content type: Research article

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  12. The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies ex...

    Authors: Georgia C. Richards, Kamal R. Mahtani, Tonny B. Muthee, Nicholas J. DeVito, Constantinos Koshiaris, Jeffrey K. Aronson, Ben Goldacre and Carl J. Heneghan

    Citation: BMC Medicine 2020 18:68

    Content type: Research article

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  13. The highest burden of hypertension is found in Sub-Saharan Africa (SSA) with a threefold greater mortality from stroke and other associated diseases. Ethnicity is known to influence the response to antihyperte...

    Authors: Anna Seeley, Josephine Prynn, Rachel Perera, Rebecca Street, Daniel Davis and Anthony O. Etyang

    Citation: BMC Medicine 2020 18:75

    Content type: Research article

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  14. We recently published in BMC Medicine an evaluation of the comparative diagnostic performance of InSilicoVA, a software to map the underlying causes of death from verbal autopsy interviews. The developers of this...

    Authors: Abraham D. Flaxman, Riley Hazard, Ian Riley, Alan D. Lopez and Christopher J. L. Murray

    Citation: BMC Medicine 2020 18:73

    Content type: Correspondence

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    The original article was published in BMC Medicine 2018 16:56

    The Correspondence to this article has been published in BMC Medicine 2020 18:69

  15. A verbal autopsy (VA) is an interview conducted with the caregivers of someone who has recently died to describe the circumstances of the death. In recent years, several algorithmic methods have been developed...

    Authors: Zehang Richard Li, Tyler H. McCormick and Samuel J. Clark

    Citation: BMC Medicine 2020 18:69

    Content type: Correspondence

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    The Correspondence to this article has been published in BMC Medicine 2020 18:73

    The Research article to this article has been published in BMC Medicine 2018 16:56

  16. Immunological damage in acute HIV infection (AHI) may predispose to detrimental clinical sequela. However, studies on the earliest HIV-induced immunological changes are limited, particularly in sub-Saharan Afr...

    Authors: Daniel M. Muema, Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Nasreen Ismail, Mary Dong, Amber Moodley, Krista L. Dong, Zaza M. Ndhlovu, Jenniffer M. Mabuka, Bruce D. Walker, Jaclyn K. Mann and Thumbi Ndung’u

    Citation: BMC Medicine 2020 18:81

    Content type: Research article

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  17. Diagnosing polycystic ovary syndrome (PCOS) during adolescence is challenging because features of normal pubertal development overlap with adult diagnostic criteria. The international evidence-based PCOS Guide...

    Authors: Alexia S. Peña, Selma F. Witchel, Kathleen M. Hoeger, Sharon E. Oberfield, Maria G. Vogiatzi, Marie Misso, Rhonda Garad, Preeti Dabadghao and Helena Teede

    Citation: BMC Medicine 2020 18:72

    Content type: Guideline

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  18. Age at menarche has been associated with various health outcomes. We aimed to identify potential causal effects of age at menarche on health-related traits in a hypothesis-free manner.

    Authors: Maria C. Magnus, Anna L. Guyatt, Rebecca B. Lawn, Annah B. Wyss, Katerina Trajanoska, Leanne K. Küpers, Fernando Rivadeneira, Martin D. Tobin, Stephanie J. London, Debbie A. Lawlor, Louise A. C. Millard and Abigail Fraser

    Citation: BMC Medicine 2020 18:71

    Content type: Research article

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  19. Geographical inequalities in overweight and obesity prevalence among children are well established in cross-sectional research. We aimed to examine how environmental area characteristics at birth are related t...

    Authors: Sam Wilding, Nida Ziauddeen, Dianna Smith, Paul Roderick, Debbie Chase and Nisreen A. Alwan

    Citation: BMC Medicine 2020 18:43

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:59

  20. School-based physical activity and running programmes, such as The Daily Mile™, are increasing in popularity globally. The aim of this research was to examine the acute impact of such classroom physical activi...

    Authors: Josephine N. Booth, Ross A. Chesham, Naomi E. Brooks, Trish Gorely and Colin N. Moran

    Citation: BMC Medicine 2020 18:62

    Content type: Research article

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  21. Gluten-free diet (GFD) decreases the quality of life of celiac disease (CD) patients, who frequently ask to occasionally ingest gluten-containing food. We evaluated CD patients reporting voluntary and occasion...

    Authors: Luca Elli, Karla Bascuñán, Lorenzo di Lernia, Maria Teresa Bardella, Luisa Doneda, Laura Soldati, Stefania Orlando, Francesca Ferretti, Vincenza Lombardo, Giulio Barigelletti, Alice Scricciolo, Sabrina Fabiano, Maurizio Vecchi and Leda Roncoroni

    Citation: BMC Medicine 2020 18:42

    Content type: Research article

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    The Commentary to this article has been published in BMC Medicine 2020 18:70

  22. Social prescribing is a way of addressing the ‘non-medical’ needs (e.g. loneliness, debt, housing problems) that can affect people’s health and well-being. Connector schemes (e.g. delivered by care navigators ...

    Authors: Stephanie Tierney, Geoff Wong, Nia Roberts, Anne-Marie Boylan, Sophie Park, Ruth Abrams, Joanne Reeve, Veronika Williams and Kamal R. Mahtani

    Citation: BMC Medicine 2020 18:49

    Content type: Research article

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  23. Multimorbidity, the co-occurrence of two or more diseases in one patient, is a frequent phenomenon. Understanding how different diseases condition each other over the lifetime of a patient could significantly ...

    Authors: Nils Haug, Carola Deischinger, Michael Gyimesi, Alexandra Kautzky-Willer, Stefan Thurner and Peter Klimek

    Citation: BMC Medicine 2020 18:44

    Content type: Research Article

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  24. Accurate and timely cause of death (COD) data are essential for informed public health policymaking. Medical certification of COD generally provides the majority of COD data in a population and is an essential...

    Authors: John D. Hart, Renee Sorchik, Khin Sandar Bo, Hafizur R. Chowdhury, Saman Gamage, Rohina Joshi, Viola Kwa, Hang Li, Buddhika P. K. Mahesh, Deirdre Mclaughlin, Lene Mikkelsen, Janet Miki, Roderick Napulan, Rasika Rampatige, Matthew Reeve, Carmina Sarmiento…

    Citation: BMC Medicine 2020 18:74

    Content type: Research article

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  25. Despite attempts to apply standard methods proven to work in high-income nations, nearly all civil registration and vital statistics (CRVS) systems in low- and middle-income countries are failing to achieve ad...

    Authors: Daniel Cobos Muñoz, Don de Savigny, Renee Sorchik, Khin Sandar Bo, John Hart, Viola Kwa, Xavier Ngomituje, Nicola Richards and Alan D. Lopez

    Citation: BMC Medicine 2020 18:67

    Content type: Debate

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  26. Globally, an estimated two-thirds of all deaths occur in the community, the majority of which are not attended by a physician and remain unregistered. Identifying and registering these deaths in civil registra...

    Authors: Tim Adair, Megha Rajasekhar, Khin Sandar Bo, John Hart, Viola Kwa, Md. Ashfaqul Amin Mukut, Matthew Reeve, Nicola Richards, Margarita Ronderos-Torres, Don de Savigny, Daniel Cobos Muñoz and Alan D. Lopez

    Citation: BMC Medicine 2020 18:65

    Content type: Debate

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  27. The need to monitor the Sustainable Development Goals (SDGs) and to have access to reliable and timely mortality data has created a strong demand in countries for tools that can assist them in this. ANACONDA (...

    Authors: Lene Mikkelsen, Kim Moesgaard, Michael Hegnauer and Alan D. Lopez

    Citation: BMC Medicine 2020 18:61

    Content type: Research article

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  28. The majority of low- and middle-income countries (LMICs) do not have adequate civil registration and vital statistics (CRVS) systems to properly support health policy formulation. Verbal autopsy (VA), long use...

    Authors: Riley H. Hazard, Mahesh P. K. Buddhika, John D. Hart, Hafizur R. Chowdhury, Sonja Firth, Rohina Joshi, Ferchito Avelino, Agnes Segarra, Deborah Carmina Sarmiento, Abdul Kalam Azad, Shah Ali Akbar Ashrafi, Khin Sandar Bo, Violoa Kwa and Alan D. Lopez

    Citation: BMC Medicine 2020 18:60

    Content type: Research article

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  29. Improving civil registration and vital statistics (CRVS) systems requires strengthening the capacity of the CRVS workforce. The improvement of data collection and diagnostic practices must be accompanied by ef...

    Authors: Tim Adair, Nicola Richards, Avita Streatfield, Megha Rajasekhar, Deirdre McLaughlin and Alan D. Lopez

    Citation: BMC Medicine 2020 18:46

    Content type: Debate

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  30. Antibiotic resistance (ABR) poses a major threat to health and economic wellbeing worldwide. Reducing ABR will require government interventions to incentivise antibiotic development, prudent antibiotic use, in...

    Authors: Mark Jit, Dorothy Hui Lin Ng, Nantasit Luangasanatip, Frank Sandmann, Katherine E. Atkins, Julie V. Robotham and Koen B. Pouwels

    Citation: BMC Medicine 2020 18:38

    Content type: Correspondence

    Published on:

  31. It is unknown whether interventions known to improve the healthcare response to domestic violence and abuse (DVA)—a global health concern—are effective outside of a trial.

    Authors: Alex Hardip Sohal, Gene Feder, Kambiz Boomla, Anna Dowrick, Richard Hooper, Annie Howell, Medina Johnson, Natalia Lewis, Clare Robinson, Sandra Eldridge and Chris Griffiths

    Citation: BMC Medicine 2020 18:48

    Content type: Research article

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  32. Spread of malaria and antimalarial resistance through human movement present major threats to current goals to eliminate the disease. Bordering the Greater Mekong Subregion, southeast Bangladesh is a potential...

    Authors: Ipsita Sinha, Abdullah Abu Sayeed, Didar Uddin, Amy Wesolowski, Sazid Ibna Zaman, M. Abul Faiz, Aniruddha Ghose, M. Ridwanur Rahman, Akramul Islam, Mohammad Jahirul Karim, Anjan Saha, M. Kamar Rezwan, Abul Khair Mohammad Shamsuzzaman, Sanya Tahmina Jhora, M. M. Aktaruzzaman, Hsiao-Han Chang…

    Citation: BMC Medicine 2020 18:45

    Content type: Research article

    Published on:

  33. Functional somatic symptoms and disorders are common and complex phenomena involving both bodily and brain processes. They pose major challenges across medical specialties. These disorders are common and have ...

    Authors: Christopher Burton, Per Fink, Peter Henningsen, Bernd Löwe and Winfried Rief

    Citation: BMC Medicine 2020 18:34

    Content type: Opinion

    Published on:

  34. Anxiety and depression are more common in children with obesity than in children of normal weight, but it is unclear whether this association is independent of other known risk factors. Interpretation of resul...

    Authors: Louise Lindberg, Emilia Hagman, Pernilla Danielsson, Claude Marcus and Martina Persson

    Citation: BMC Medicine 2020 18:30

    Content type: Research article

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  35. Previous research reported that individuals prescribed antibiotics frequently develop antimicrobial resistance. The objective of this study was to evaluate whether frequent antibiotic use is associated with re...

    Authors: Tjeerd Pieter van Staa, Victoria Palin, Yan Li, William Welfare, Timothy W. Felton, Paul Dark and Darren M. Ashcroft

    Citation: BMC Medicine 2020 18:40

    Content type: Research article

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  36. The cytokine IL-17 is a key player in autoimmune processes, while the cytokine IL-6 is responsible for the chronification of inflammation. However, their roles in type 1 diabetes development are still unknown.

    Authors: Anne Jörns, Daichi Ishikawa, Hiroki Teraoku, Toshiaki Yoshimoto, Dirk Wedekind and Sigurd Lenzen

    Citation: BMC Medicine 2020 18:33

    Content type: Research article

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  37. Iron deficiency (ID) is a major public health burden in African children and accurate prevalence estimates are important for effective nutritional interventions. However, ID may be incorrectly estimated in Afr...

    Authors: John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Alireza Morovat, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Rosie J. Crane, James A. Berkley, Swaib A. Lule, Clare Cutland, Sodiomon B. Sirima, Amidou Diarra, Alfred B. Tiono, Philip Bejon, Shabir A. Madhi…

    Citation: BMC Medicine 2020 18:31

    Content type: Research article

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  38. The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquine (AS-AQ), with amodiaquine being also wi...

    Authors: Michael T. Bretscher, Prabin Dahal, Jamie Griffin, Kasia Stepniewska, Quique Bassat, Elisabeth Baudin, Umberto D’Alessandro, Abdoulaye A. Djimde, Grant Dorsey, Emmanuelle Espié, Bakary Fofana, Raquel González, Elizabeth Juma, Corine Karema, Estrella Lasry, Bertrand Lell…

    Citation: BMC Medicine 2020 18:47

    Content type: Research article

    Published on:

Announcement: COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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