Advertisement
Minireview
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem. Flares can be complex and expensive to...
BMC Medicine 2017 15:158
Published on: 18 August 2017
Commentary
Advances in deep sequencing technology have led to developments in personalized medicine. Here, we describe the implications of a recent investigation that sequenced ctDNA from the plasma of non-small cell lun...
BMC Medicine 2017 15:157
Published on: 17 August 2017
Commentary
According to data presented at the 2017 American Society of Oncology (ASCO) Annual Meeting, with more than 4 years of follow-up, ibrutinib continues to provide clinical utility in chronic lymphocytic leukemia ...
BMC Medicine 2017 15:156
Published on: 16 August 2017
Research article
Unintended repeat conceptions can result in emotional, psychological and educational harm to young women, often with enduring implications for their life chances. This study aimed to identify which young women...
BMC Medicine 2017 15:155
Published on: 15 August 2017
Research article
Changes in the microvasculature associated with pre-eclampsia and gestational hypertension have been proposed as a potential pathway in the development of cardiovascular disease. We examined whether gestationa...
BMC Medicine 2017 15:153
Published on: 14 August 2017
Research article
The risk of psoriasis in patients with breast cancer is largely unknown, as available evidence is limited to case findings. We systematically examined the incidence and risk factors of psoriasis in patients wi...
BMC Medicine 2017 15:154
Published on: 11 August 2017
Research article
Decreasing trends in measles mortality have been reported in recent years. However, such estimates of measles mortality have depended heavily on assumed regional measles case fatality risks (CFRs) and made lit...
BMC Medicine 2017 15:151
Published on: 10 August 2017
Research article
Recently, health screening recommendations have gone beyond screening for early-stage, asymptomatic disease to include “screening” for presently experienced health problems and symptoms using self-report quest...
BMC Medicine 2017 15:150
Published on: 9 August 2017
Research article
Pregnancy and pregnancy loss may be linked to cardiovascular disease (CVD). However, the evidence is still inconsistent, especially in East Asians, whose reproductive patterns differ importantly from those in ...
BMC Medicine 2017 15:148
Published on: 8 August 2017
Commentary
Mehdizadeh and colleagues recently described the prevalence of General Medical Council regulatory performance assessments by doctors’ country of primary medical qualification. This article has caused anger wit...
BMC Medicine 2017 15:149
Published on: 7 August 2017
Research article
The use of the point-of-care lateral flow lipoarabinomannan (LF-LAM) test may expedite tuberculosis (TB) diagnosis in HIV-positive patients. However, the test’s clinical utility is poorly defined outside sub-S...
BMC Medicine 2017 15:145
Published on: 4 August 2017
Research article
The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria through a systematic ...
BMC Medicine 2017 15:147
Published on: 3 August 2017
Research article
Clinicians are inaccurate at predicting survival. The ‘Surprise Question’ (SQ) is a screening tool that aims to identify people nearing the end of life. Potentially, its routine use could help identify patient...
BMC Medicine 2017 15:139
Published on: 2 August 2017
Review
Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in mu...
BMC Medicine 2017 15:144
Published on: 1 August 2017
Research article
There is evidence that social anxiety disorder (SAD) is a prevalent and disabling disorder. However, most of the available data on the epidemiology of this condition originate from high income countries in the...
BMC Medicine 2017 15:143
Published on: 31 July 2017
Research article
Dementia and diabetes mellitus are common long-term conditions and co-exist in a large number of older people. People living with dementia (PLWD) may be less able to manage their diabetes, putting them at incr...
BMC Medicine 2017 15:141
Published on: 28 July 2017
Research article
Cognitive impairment of various kinds is common in older people admitted to hospital, but previous research has usually focused on single conditions in highly-selected groups and has rarely examined associatio...
BMC Medicine 2017 15:140
Published on: 27 July 2017
Research Article
Antibiotic resistance is threatening to make gonorrhoea untreatable. Point-of-care (POC) tests that detect resistance promise individually tailored treatment, but might lead to more treatment and higher levels...
BMC Medicine 2017 15:142
Published on: 26 July 2017
Opinion
Assessments of vaccine efficacy and safety capture only the minimum information needed for regulatory approval, rather than the full public health value of vaccines. Vaccine efficacy provides a measure of prop...
BMC Medicine 2017 15:138
Published on: 26 July 2017
Research article
Postoperative ischemia is a frequent phenomenon in patients with brain tumors and is associated with postoperative neurological deficits and impaired overall survival. Particularly in the field of cardiac and ...
BMC Medicine 2017 15:137
Published on: 25 July 2017
Opinion
Compassionate use is the use of unapproved drugs outside of clinical trials. So far, compassionate use regulations have been introduced in the US, Canada, many European countries, Australia and Brazil, and tre...
BMC Medicine 2017 15:136
Published on: 24 July 2017
Opinion
Surrogate outcomes are not intrinsically beneficial to patients, but are designed to be easier and faster to measure than clinically meaningful outcomes. The use of surrogates as an endpoint in clinical trials...
BMC Medicine 2017 15:134
Published on: 21 July 2017
Review
Adverse psychosocial exposures in early life, namely experiences such as child maltreatment, caregiver stress or depression, and domestic or community violence, have been associated in epidemiological studies ...
BMC Medicine 2017 15:135
Published on: 20 July 2017
Review
Environmental and lifestyle changes, in addition to the ageing of populations, are generally believed to account for the rapid global increase in type 2 diabetes prevalence and incidence in recent decades.
BMC Medicine 2017 15:131
Published on: 19 July 2017
Review
The advent of rapid and inexpensive sequencing technology allows scientists to decipher heterogeneity within primary tumours, between primary and metastatic sites, and between metastases. Charting the evolutio...
BMC Medicine 2017 15:133
Published on: 18 July 2017
