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  1. Content type: Research article

    In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), without testing for glucose-...

    Authors: W. Robert Taylor, Htee Khu Naw, Kathryn Maitland, Thomas N. Williams, Melissa Kapulu, Umberto D’Alessandro, James A. Berkley, Philip Bejon, Joseph Okebe, Jane Achan, Alfred Ngwa Amambua, Muna Affara, Davis Nwakanma, Jean-Pierre van Geertruyden, Muhindo Mavoko, Pascal Lutumba…

    Citation: BMC Medicine 2018 16:11

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  2. Content type: Research article

    Antidepressant exposure during pregnancy has been associated with an increased risk of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in several observational studies. We pe...

    Authors: Daniel R. Morales, Jim Slattery, Stephen Evans and Xavier Kurz

    Citation: BMC Medicine 2018 16:6

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  3. Content type: Research article

    Elective surgeries can be associated with significant harm to older adults. The present study aimed to identify the prognostic factors associated with the development of postoperative complications among older...

    Authors: Jennifer Watt, Andrea C. Tricco, Catherine Talbot-Hamon, Ba’ Pham, Patricia Rios, Agnes Grudniewicz, Camilla Wong, Douglas Sinclair and Sharon E. Straus

    Citation: BMC Medicine 2018 16:2

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  4. Content type: Research article

    The use of cardiovascular medication for the primary prevention of cardiovascular disease (CVD) is potentially inappropriate when potential risks outweigh the potential benefits. It is unknown whether deprescr...

    Authors: Clare H. Luymes, Rosalinde K. E. Poortvliet, Nan van Geloven, Margot W. M. de Waal, Yvonne M. Drewes, Jeanet W. Blom, Nynke Smidt, Willem J. J. Assendelft, Wilbert B. van den Hout, Wouter de Ruijter and Mattijs E. Numans

    Citation: BMC Medicine 2018 16:5

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  5. Content type: Research article

    Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not ...

    Authors: Zoe Paskins, Rebecca Whittle, Alyshah Abdul Sultan, Sara Muller, Milica Blagojevic-Bucknall, Toby Helliwell, Samantha Hider, Edward Roddy and Christian Mallen

    Citation: BMC Medicine 2018 16:4

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  6. Content type: Research article

    Epidemiological studies suggest that reduced exposure to varicella might lead to an increased risk for herpes zoster (HZ). Reduction of exposure to varicella is a consequence of varicella vaccination but also ...

    Authors: Johannes Horn, Oliver Damm, Wolfgang Greiner, Hartmut Hengel, Mirjam E. Kretzschmar, Anette Siedler, Bernhard Ultsch, Felix Weidemann, Ole Wichmann, André Karch and Rafael T. Mikolajczyk

    Citation: BMC Medicine 2018 16:3

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  7. Content type: Opinion

    Changes in climate, in conjunction with other drivers of mobility, shape human migration. While there is an increasing focus on the adaptive potential of migration, the health impacts of climate-related migrat...

    Authors: Patricia Schwerdtle, Kathryn Bowen and Celia McMichael

    Citation: BMC Medicine 2018 16:1

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  8. Content type: Opinion

    Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects in the population. In addition, intervention combinations can have comp...

    Authors: M. Elizabeth Halloran, Kari Auranen, Sarah Baird, Nicole E. Basta, Steven E. Bellan, Ron Brookmeyer, Ben S. Cooper, Victor DeGruttola, James P. Hughes, Justin Lessler, Eric T. Lofgren, Ira M. Longini, Jukka-Pekka Onnela, Berk Özler, George R. Seage, Thomas A. Smith…

    Citation: BMC Medicine 2017 15:223

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  9. Content type: Commentary

    To achieve complete polio eradication, the live oral poliovirus vaccine (OPV) currently used must be phased out after the end of wild poliovirus transmission. However, poorly understood threats may arise when ...

    Authors: James S. Koopman

    Citation: BMC Medicine 2017 15:221

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    The original article was published in BMC Medicine 2017 15:180

    The original article was published in BMC Medicine 2017 15:175

  10. Content type: Research article

    The UK, like many high-income countries, is experiencing a worsening shortfall of general practitioners (GPs) alongside an increasing demand for their services. At the same time, factors influencing junior doc...

    Authors: Thomas C. E. Gale, Paul J. Lambe and Martin J. Roberts

    Citation: BMC Medicine 2017 15:220

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  11. Content type: Research article

    Circulating concentrations of lipid biomarkers are associated with risk of cardiovascular diseases (CVD). The evidence for a relationship with cancer risk, however, is not entirely consistent. This study aims ...

    Authors: Verena Andrea Katzke, Disorn Sookthai, Theron Johnson, Tilman Kühn and Rudolf Kaaks

    Citation: BMC Medicine 2017 15:218

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  12. Content type: Research article

    HCV treatment uptake has drastically increased in HIV-HCV coinfected patients in France since direct-acting antiviral (DAA) treatment approval, resulting in HCV cure in 63% of all HIV-HCV patients by the end o...

    Authors: Victor Virlogeux, Fabien Zoulim, Pascal Pugliese, Isabelle Poizot-Martin, Marc-Antoine Valantin, Lise Cuzin, Jacques Reynes, Eric Billaud, Thomas Huleux, Firouze Bani-Sadr, David Rey, Anne Frésard, Christine Jacomet, Claudine Duvivier, Antoine Cheret, Laurent Hustache-Mathieu…

    Citation: BMC Medicine 2017 15:217

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  13. Content type: Research article

    Major depressive disorder (MDD) is often handled as an episodic and isolated disorder, resulting in an optimistic view about its prognosis. Herein, we test the idea that the prognosis of MDD changes if we vary...

    Authors: Judith Verduijn, Josine E. Verhoeven, Yuri Milaneschi, Robert A. Schoevers, Albert M. van Hemert, Aartjan T. F. Beekman and Brenda W. J. H. Penninx

    Citation: BMC Medicine 2017 15:215

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  14. Content type: Guideline

    Populations exposed to humanitarian emergencies are particularly vulnerable to mental health problems, including new onset, relapse and deterioration of psychotic disorders. Inadequate care for this group may ...

    Authors: Giovanni Ostuzzi, Corrado Barbui, Charlotte Hanlon, Sudipto Chatterjee, Julian Eaton, Lynne Jones, Derrick Silove and Peter Ventevogel

    Citation: BMC Medicine 2017 15:197

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  15. Content type: Commentary

    This Commentary describes the situation and healthcare needs of Afghans returning to their country of origin. With more than 600,000 Afghans returned from Pakistan and approximately 450,000 Afghans returned fr...

    Authors: Ariel Higgins-Steele, David Lai, Paata Chikvaidze, Khaksar Yousufi, Zelaikha Anwari, Richard Peeperkorn and Karen Edmond

    Citation: BMC Medicine 2017 15:196

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  16. Content type: Research article

    Chronic hepatitis B virus (HBV) infection leads to liver fibrosis, which is a major risk factor in hepatocellular carcinoma (HCC) and an independent risk factor of recurrence after HCC tumor resection. The HBV...

    Authors: Seungyeul Yoo, Wenhui Wang, Qin Wang, M Isabel Fiel, Eunjee Lee, Spiros P. Hiotis and Jun Zhu

    Citation: BMC Medicine 2017 15:214

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  17. Content type: Research article

    Diagnosis of monogenic as well as atypical forms of diabetes mellitus has important clinical implications for their specific diagnosis, prognosis, and targeted treatment. Single gene mutations that affect beta...

    Authors: Vikas Bansal, Johann Gassenhuber, Tierney Phillips, Glenn Oliveira, Rebecca Harbaugh, Nikki Villarasa, Eric J. Topol, Thomas Seufferlein and Bernhard O. Boehm

    Citation: BMC Medicine 2017 15:213

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  18. Content type: Technical advance

    Epigenomes are tissue specific and thus the choice of surrogate tissue can play a critical role in interpreting neonatal epigenome-wide association studies (EWAS) and in their extrapolation to target tissue. T...

    Authors: Xinyi Lin, Ai Ling Teh, Li Chen, Ives Yubin Lim, Pei Fang Tan, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Yung Seng Lee, Joanna D. Holbrook, Keith M. Godfrey, Michael J. Meaney, Michael S. Kobor, Yap Seng Chong…

    Citation: BMC Medicine 2017 15:211

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  19. Content type: Research article

    Inflammation occurs as an immediate protective response of the immune system to a harmful stimulus, whether locally confined or systemic. In contrast, a persisting, i.e., chronic, inflammatory state, even at a...

    Authors: Maik Pietzner, Anne Kaul, Ann-Kristin Henning, Gabi Kastenmüller, Anna Artati, Markus M. Lerch, Jerzy Adamski, Matthias Nauck and Nele Friedrich

    Citation: BMC Medicine 2017 15:210

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